西地那非

枸橼酸西地那非片治疗男性勃起功能障碍有效性及安全性评价西地那非与前列腺素E1治疗勃起功能障碍的疗效比较

Evaluation of efficacy and safety of oral sildenafil citrate therapy for men with erectile dysfunction Sildenafil versus prostaglandin E_1 in the management of erectile dysfunction

西地那非对慢性低氧性肺动脉高压大鼠NO、NOS的作用

The effect of sildenafil on nitric oxide content and nitric oxide synthase activity in chronic hypoxic pulmonary hypertension in rats

B组：40例，在用西地那非治疗的同时加用维生素E（30mg/d）两组均治疗1个月。

Whereas , group B received Vitamin E ( 30 mg / d ) plus Sildenafil also for 1 month .

中国市场研究报告（ChinaMarketResearchReports）发布的中国西地那非市场2009-2018年调查报告估计，中国有5千多万男性患性功能障碍。

The Investigation Report on China Sildenafil Market , 2009-2018 put out by China Market Research Reports estimates that more than 50 million men in China suffer from sexual dysfunction .

中国市场研究报告（ChinaMarketResearchReports）发布的“中国西地那非市场2009-2018年调查报告”估计，中国有5千多万男性患性功能障碍。

The " Investigation Report on China Sildenafil Market , 2009-2018 " put out by China Market Research Reports estimates that more than 50 million men in China suffer from sexual dysfunction .

结论：西地那非治疗ED是安全有效的，IIEF5可作为评判ED疗效的可靠指标。

Conclusions : Oral sildenafil is effective for various ED and IIEF 5 value is a reliable reference .

西地那非对荷S180小鼠抗肿瘤作用的实验

Anti-tumor Effect of Sildenafil on S180 Sarcoma

西地那非治疗ED平均有效率达80%以上，成为治疗ED的首选手段。

The success rate of sildenafil amounts to an average of over 80 % , and sildenafil has become the first choice for patients with ED.

结果：西地那非治疗ED病人的总疗效率为80.7%，IIEF5值上升幅度与西地那非疗效呈正相关。

Results : Overall satisfaction with sildenafil was 80.7 % and a significantly positive correlation existed between baseline IIEF 5 and that after oral sildenafil .

本文通过对青霉素、炔诺酮、维生素C、心钠素、西地那非等几十种药物的发现过程进行了分门别类的详细描述，总结出了6条发现新药的途径。

In this article the course of discovery of Penicillin 、 Norethindrone 、 Vc 、 ANP 、 Sildenafil etc was described in detail based on their kinds , and summed up 6 methods for the discovery of new drugs .

GBS患者CSF中MBP-IgG阳性率与发病天数有关。西地那非的起效时间和维持时间的研究进展

And was relevant to the onset days of GBS . Advances in Researches on the Onset and Duration of the Action of Sildenafil

结论ED患者对西地那非治疗的依从性差，健康教育有助于改善依从性。

Conclusion Our study shows that the compliance of sildenafil for patients with ED is poor and health education is an effective intervening measure to improve it .

自1998年西地那非用于临床治疗ED以来，ED的治疗进入了一个新阶段。西地那非以其疗效确切、安全性高成为首选治疗。

The management of ED has entered a new stage since sildenafil was used to treat ED in 1998 . Sildenafil became the first-line treatment for its efficacy and safty .

目的明确维持性血液透析（MHD）男性患者勃起障碍的发病率，及评价西地那非的疗效与副作用。

Objective To estimate the prevalence of erectile dysfunction ( ED ) among the patients undergoing manintenance hemodialysis ( MHD ), and evaluate the efficacy and the adverse effects of sildenafil for ED.

另有报道指出，磷酸二酯酶-5抑制剂西地那非（sildenafil，伟哥）通过增加cGMP的积聚激活PKG，进而保护缺血／再灌注的心肌细胞。

It has also been reported that inhibition of phosphodiesterase-5 with sildenafil ( Viagra ) which can augment cGMP accumulation protects cardiomyocytes from ischemia / reperfusion injury via a PKG-dependent mechanism .

生精细胞凋亡方面，经西地那非、LC单独和联合治疗后均比DM模型组降低，且联合治疗比单独用药组明显降低。

In the aspect of apoptosis of spermatogenic cell , compared with DM model group , groups with combination and alone of sildenafil and LC were significant decreased , and the combination therapy group was more significant decrease than alone therapy group .

目的比较口服西地那非（SIL）与静脉应用前列地尔（PGE1）治疗先天性心脏病（先心病）术后肺动脉高压（PH）的早期疗效。

Objective To compare the effects of oral Sildenafil ( SIL ) and intravenous prostaglandin E_1 ( Alprostadil , PGE_1 ) in treatment of postoperative pulmonary hypertension ( PH ) associated with congenital heart defects ( CHD ) .

磷酸二酯酶5（PDE5）抑制剂西地那非的问世使男性勃起功能障碍（ED）的治疗手段发生了根本性的改变。

Since the introduction of the phosphodiesterase type 5 ( PDE-5 ) inhibitor sildenafil in 1998 , there has been a fundamental change in the treatment of erectile dysfunction ( ED ) .

伐地那非是一种强效、高选择性的5型磷酸二酯酶（PDE5）抑制剂，对PDE5的抑制作用约为西地那非的10倍。

Vardenafil is a potent and highly selective phosphodiesterase type 5 ( PDE5 ) inhibitor with a potency about 10-fold higher than sildenafil .

39例ED患者中，13例应用西地那非治疗，其中9例保留血管神经束者治疗前后IIEF-5评分分别为（5.3±1.2）和（20.6±2.3）（P<0.05）；

Of these 39 ED patients , 13 tried sildenafil citrate . For 9 cases who underwent nerve-sparing RC , the IIEF-5 score were ( 5.3 ± 1.2 ) at pretreatment and ( 20.6 ± 2.3 ) after treatment respectively ( P < 0.05 );

连续口服枸橼酸西地那非治疗顽固性及心因性勃起功能障碍的疗效分析

Continuous oral viagra for the treatment of refractory psychogenic erectile dysfunction

西地那非治疗肺动脉高压的临床研究

The Study on the Effect of Sildenafil in Pulmonary Hypertension Therapy

西地那非以其疗效确切、安全性高成为首选治疗。

Sildenafil became the first-line treatment for its efficacy and safty .

毛细管电泳法测定性保健品中的西地那非

Determination of Sildenafil in Medicines for Erectile Dysfunction by Capillary Electrophoresis

伟哥，又名西地那非，由辉瑞公司生产。

Viagra , also known as sildenafil , is manufactured by Pfizer Inc.

西地那非应用于高原病的研究进展

Application of sildenafil to mountain sickness : a research progress

目的对保健品中掺入的西地那非进行定量分析。

OBJECTIVE To determine the content of Sildenafll mixed in health products .

西地那非对雄性猕猴性功能的影响

The influence of sildenafil on the sexual function of male Rhesus macaques

目的建立检查壮腰补肾丸中非法掺入枸橼酸西地那非的方法。

OBJECTIVE To identify Sildenafile citrate mixed illegally in Zhuangyao Bushen pill .

国产枸橼酸西地那非片治疗男性勃起功能障碍疗效和安全性的临床研究

Efficacy and Safety of Oral Domestic Sildenafil in the Treatment of Erectile Dysfunction