蛋白质聚集

热休克蛋白对短暂心肌缺血所致蛋白质聚集的影响

Effects of Heat Shock Proteins on Protein Aggregation Induced by Transient Myocardial Ischemia

研究了细胞内存在的分子伴侣、蛋白质聚集和大分子拥挤环境对蛋白质折叠的影响。

The effects of molecular chaperones , protein aggregation and macromolecular crowding on protein folding have been studied .

近来有人提出当某种蛋白质聚集在一个X染色体特定部位时，这条染色体将保持活跃，并抑制其“自杀基因”XIST。

Recently it has been proposed that an X remains active when certain proteins aggregate at a specific spot on the chromosome , shutting down its " suicide gene " XIST .

铜锌超氧化物歧化酶（SOD1）的突变引起结构和金属结合性质的变化，及由此导致的氧化毒性和蛋白质聚集作用可能是导致ALS的重要原因之一。

The structural and the metal-binding variations in Cu Zn superoxide dismutase ( SOD1 ) mutants have been linked to many kinds of neurodegenerative diseases , in particular , amyotrophic lateral sclerosis , due to their oxidative damage and aggregation .

脂质氧化诱导的大豆蛋白质聚集机理的研究

Mechanism of Aggregation of Soybean Proteins Induced by Lipid Oxidation

什么因素会影响蛋白质聚集，其机制如何？

Which factors will affect the proteins aggregation and what is the mechanism ?

老年性痴呆症的一个标志就是脑组织中由于蛋白质聚集形成的斑块。

One of the hallmarks of Alzheimer 's disease is the formation of plaques made of protein aggregates in the brain tissue .

由于蛋白质聚集微粒表面的极性吸附点减少，致使醇法大豆浓缩蛋白无法获得有效的塑化作用。

Due to the lack of polar sites on protein conglomerates , the alcoholic leached SPC did not get enough plasticizing effect from existed water .

利用脂肪氧合酶、亚油酸和大豆分离蛋白构建的模拟体系，研究了脂质氧化诱导的大豆蛋白质聚集的机理。

A model system consisting of linoleic acid , lipoxygenase and soybean protein isolate was established to investigate the mechanism of aggregation of soybean proteins induced by lipid oxidation .

针对蛋白质聚集问题，开展抑制聚集方法研究，发现与蛋白质带有同种电荷的离子交换介质能够很好地抑制折叠中间体聚集从而促进蛋白质复性。

Herein we found that electrostatic repulsion between like-charged protein and ion exchange gel beads can greatly suppress the aggregation of folding intermediates , leading to the significant increase of native protein recovery .

目前ALS的病因及发病机制尚不十分清楚，推测有以下几种：线粒体功能障碍、蛋白质异常聚集、兴奋毒作用、轴浆运输障碍、氧化应激、生长因子缺乏和炎症等。

Until now the exact mechanisms underlying ALS are still less clear . Several hypotheses to explain motor neuron degeneration have been proposed , including mitochondrial dysfunction , protein aggregate formation , excitotoxicity , axonal transport malfunction , oxidative damage , lack of growth factors , and inflammation .

蛋白质分子聚集状态对大豆蛋白溶胀性能的影响

Effect of Molecule Aggregation on the Swelling Ability of Soy Protein Preparations

末期表现为这些错误折叠的蛋白质大量聚集并导致组织与细胞的巨大破坏。

The end-stage consists of large aggregates of these misfolded proteins , which cause massive tissue and cell damage .

抗冻剂可以有效防止在冷冻条件下蛋白质的聚集和变性，从而使得鱼糜在冷冻保藏后仍然可以保持较好的凝胶强度和口感。

Antifreeze could be effective in preventing aggregation and denaturation of protein under freezing storage conditions , allowed surimi to maintain a good gel strength and texture after frozen preservation .

水稻齿叶矮缩病毒S8基因编码的结构蛋白质及其自聚集性质

Self aggregation of the Structural Protein Encoded by Rice Ragged Stunt Oryzavirus Genome Segment 8

说明海藻糖的主要作用是有效抑制蛋白质分子间聚集，因此在一定范围内提高其浓度可促进蛋白质复性，从而提高复性收率。

The result indicated that the main role of trehalose was to prevent intermolecular aggregation . Therefore , in a proper range of concentration , increasing trehalose concentration could facilitate refolding of protein and increase refolding yield .

在体系中，共聚物与脱辅基细胞色素c之间的相互作用和共聚物与蛋白质自身的疏水聚集之间存在竞争。

A competition exists between the interaction of the copolymer with apo cyt c and the self-aggregation of PTMA or apo cyt c alone .

茜素红与蛋白质分子Langmuir吸附聚集反应研究

Langmuir aggregation of alizarin red in protein macromolecule

本文以纳米金和纳米铁（Ⅲ）为探针，基于纳米粒子在蛋白质模板上的聚集，应用共振光散射（RLS）技术对蛋白质纳米粒子共振光散射探针进行了研究，建立了高灵敏度的蛋白质检测方法。

By using a resonance light scattering ( RLS ) technique , the resonance light scattering probes of nanoparticles are studied , and a highly sensitive method for protein determination based on the aggregation of nanoparticles on protein template is described .

盐溶性蛋白热稳定性的研究显示，随着热处理时间的延长和温度的升高，蛋白质热变性和聚集的速率明显增大。

Studies of thermal stability of salt soluble protein showed that , the rate of protein thermal denaturation and aggregation was significantly accelerated with the extension of heating time and increased heating temperature .

热稳定性的研究显示，蛋白溶液的浊度随热处理时间的延长而增加，蛋白质逐渐发生变性和聚集，且随着热处理温度的升高，蛋白质热变性和聚集的速率明显加快。

Studies of thermal stability showed that the turbidity of protein solution gradually increased with extension of the heating treatment time , indicating occurrence of protein denaturation and aggregation of molecules . And the rate of protein thermal denaturation and aggregation was significantly accelerated with increased heating treatment temperature .

在一定条件下，Cr（OH）3纳米粒子和蛋白质通过静电相互作用，导致纳米粒子在蛋白质上发生聚集。

Under some conditions , Cr ( OH ) _3 nanoparticles and protein can interact by electrostatic forces and result in aggregation of the Cr ( OH ) _3 nanoparticles on the protein suface .

正确的二硫键可以稳定蛋白质的空间结构，错误的二硫键导致蛋白质不稳定，进而导致蛋白质聚集或被降解。

Correct disulfide bonds can stabilize protein structure , on the contrary , incorrect disulfide bond formation of proteins may leads to protein aggregation or degradation .