药物晶型

固体制剂工艺对药物晶型的影响

Effect of Manufacturing Processes of Solid Dosage Forms on Polymorphism of Drugs

药物晶型的分析方法

Methods for the analysis of drug crystal forms

同时介绍了结晶技术在药物晶型控制、压缩性能和释放性能改进方面的应用。

At the same time , the application of crystallization technology in controlling particle morphology , improving compression and delivery properties is introduced also .

固体药物多晶型的研究进展

Progress on the Study of Solid Drug Polymorphism

讨论了药物多晶型对理化性质、生物利用度、相关制剂的影响。

The impact of polymorphism on characterization , bioavailability and formulation of drug were discussed .

结果药物的晶型消失，累积溶出速率明显增加。

RESULTS The crystal form of drug disappeared in the dispersion and the cumulative dissolution increased evidently .

药物多晶型与有效性

Polymorphism and Drug Availability

目前，该药物已有四种晶型被专利保护，这使得国内企业在该产品的生产竞争中处于不利地位，为了突破专利的限制，本文对PCERG-1102的多晶型行为进行系统研究。

Currently , four crystal forms have already been under the protection of patent , which makes domestic enterprises at a disadvantage in the competition of their production .