自发性流产

目的：评价主动免疫联合hCG治疗原因不明反复自发性流产的临床疗效，寻求最佳治疗方案。

Objective : To evaluate the effect of clinical treatment with active immunotherapy combined with human chorionic gonadotropin ( hCG ) among patients with unexplained recurrent spontaneous abortion ( URSA ) .

单纯疤疹病毒-2型（HSV-2）是某些新生儿先天性畸形和自发性流产的原因。

Herpes simplex virus type 2 ( HSV-2 ) is a cause of congenital abnormalities in the newborn and sometimes spontaneous abortion in the early stage of gestation .

方法应用ELISA方法检测了186例自发性流产患者血清中ATAb，并以56例正常育龄妇女作为对照。

Methods The ATAb was detected by ELISA in 186 recurrent spontaneous aborting women and 56 normal fertile women .

方法：将385例原发性原因不明反复自发性流产患者分为3组，A组166例，接受主动免疫联合hCG治疗；

Method : 385 cases with primary URSA were divided into three groups : 166 cases in group A , treated with active immunotherapy combined with hCG ;

结论：主动免疫联合hCG治疗原因不明反复自发性流产疗效最好，值得在临床中推广应用。

Conclusion : The therapeutic method of active immunotherapy combined with hCG is better than others on the treatment of URSA , which worth widespread application in clinics .

应用ELISA方法检测了186例自发性流产患者血清中抗精子抗体（AsAb）、抗子宫内膜抗体（EMAb）与抗弓形虫抗体（ATAb），并以56例正常育龄妇女作为对照。

The circulating antibodies AsAb , EMAb and ATAb were detected in 186 women with recurrent spontaneous abortion and 56 normal fertile women by means of ELISA .

目的：探讨反复自发性流产（RSA）与支原体感染和抗心磷脂抗体（ACA）之间的关系及不孕症与支原体感染和抗精子抗体（ASA）之间的关系。

AIM : To elucidate the association of recurrent spontaneous abortion ( RSA ) with mycoplasma infection and anticardiolipin antibodies ( ACA ) , and the relationship of sterility to mycoplasma infection and antisperm antibodies ( ASA ) .

妊娠早期自发性流产的药物及手术清宫处理的比较

Medical vs surgical evacuation of first - trimester spontaneous abortion

妊娠早期反复自发性流产与患者免疫因素的关系

The Relation Between Recurrent Spontaneous Abortion and Immune Factors During Early Period of Pregnancy

自发性流产小鼠模型主动脉旁淋巴结CD45~+CD86~+细胞亚群分析

CD45 ~ + CD86 ~ + cells isolated from para-aortic lymph nodes in a murine abortion-prone model

不良孕产史和自发性流产夫妇Dp~+、Gp~+染色体研究

Dp ~ + Gp ~ + Chromosome Study on the Abnormal Delivery . History and Spontaneous Abortions Man and Wife

提示染色体异常、感染、血型不合、器质性病变与反复自发性流产相关。

It showed that chromosome abnormality , infection blood group incompatibility and organic lesions were connected with frequentative spontaneous abortions .

自发性流产CBA/J×DBA/2小鼠母-胎界面DX5~+CD69~+细胞的浸润

Infiltration of DX5 ~ + CD69 ~ + cells at the feto-maternal interface in spontaneous abortion CBA / J × DBA / 2 mice

非整倍体是人类生殖生物学中的重要问题，是引起自发性流产和新生儿中多种先天性畸形综合征的主要原因。

Aneuploidy is an important point at issue in human reproductive biology , accounting for both a major proportion of miscarriages and various congenital malformation syndromes among newborns .

结论1.妊娠过程中，NKT细胞可能是滋养层分泌细胞因子的主要细胞。2.原因不明自发性复发性流产的发生，可能与NKT细胞失调相关。

In the course of pregnancy , NKT cells may be the major secreting cells in the trophoblast.2.Unexplained recurrent spontaneous abortion occurred , may be related to NKT cells disorders .

结果1.正常妊娠组与原因不明自发性复发性流产组，在妊娠过程中，CD3+T细胞数量无显著性变化。

Normal pregnancy and unexplained recurrent spontaneous abortion group , in the course of pregnancy , classical CD3 + T cells without significant changes .