脂肪酸合酶

分光光度法测定脂肪酸合酶（FAS）的活性；

The activity of fatty acid synthase ( FAS ) was detected by spectrophotometry .

脂肪酸合酶抑制剂&浅蓝菌素阻遏K562细胞增殖及诱导凋亡的实验研究

Proliferation inhibition and apoptosis induction of K562 cells by fatty acid synthase inhibitor & cerulenin

实时定量PCR分析脂肪酸合酶在口腔鳞癌中的表达

Analysis of gene expression of FAS in squamous cell carcinoma of the oral cavity by the method of real-time quantitative PCR

自然界中脂肪酸合酶（FAS）以FASⅠ和FASⅡ两种形式存在。

Natural Fatty Acid Synthase ( FAS ) exists in two different forms as FAS I and FAS II .

背景与目的研究表明在许多肿瘤组织中脂肪酸合酶（FAS）呈高表达，酶活性增强且与不良预后有关。

Background and objective Fatty acid synthase ( FAS ) is differentially overexpressed and hyperactivated in many tumors and indicates poor prognosis .

结论口腔鳞癌组织和正常组织中的FAS表达有显著差异。实时定量PCR方法简便、快速、高效，并能相对定量内源性脂肪酸合酶在口腔鳞癌组织中的表达。

Conclusion Real-time quantitative PCR provides a method for monitoring the expression of fatty acid synthetic activity in squamous cell carcinoma , adjacent and normal tissues .

脂肪酸合酶（FAS）是一种多功能复合酶，是体内合成脂肪途径中的一个关键酶。

Fatty acid synthase ( Fas ) is a multifunctional composite enzyme , is synthesized in vivo fat pathway of a key enzyme .

目的探讨脂肪酸合酶抑制剂&浅蓝菌素对K562白血病细胞增殖的影响及机制，并观察浅蓝菌素对人皮肤成纤维细胞增殖的影响。

Objective To investigate the effect of fatty acid synthase ( FAS ) inhibitor & cerulenin on K562 leukemia cells and its mechanism .

最新报道脂肪酸合酶（FAS）是治疗肥胖症的潜在靶部位，但目前已知的FAS抑制剂还很少。

Fatty acid synthase ( FAS ) is reported as a potential new therapeutic target for obesity . However , there are limited known FAS inhibitors presently .

为了从植物材料中筛选有抗癌活性的物质，我们选择了肿瘤中普遍高表达的脂肪酸合酶（FAS）为靶标。

For the purpose of finding anticancer bioactive components from plant materials , we select the over-expressed enzyme in cancer tissues , fatty acid synthase ( FAS ), as our target .

本研究利用酶动力学方法测定了边茶萃取物对脂肪酸合酶（fattyacidsynthase，FAS，E.C.2.3.1.85）的抑制作用，近几年研究报道该酶是减肥和抑癌的双重潜在靶点。

The inhibition on Fatty acid synthase ( E.C.2.1.3.85 , FAS ) by the extracts of brick tea is measured by inhibition kinetics . FAS has been reported as a potential new therapeutic target for both cancer and obesity .

油茶籽提取物对脂肪酸合酶的抑制作用

Inhibition of Fatty Acid Synthase with Extract of Oiltea Seed

脂肪酸合酶&特异性肿瘤治疗靶点

Fatty Acid Synthase : Specific Target for Cancer Therapy

脂肪酸合酶抑制剂阻遏人结肠癌细胞增殖的实验研究

An Experiment Report for Fatty Acid Synthase Inhibitor Suppresses the Proliferation of Human

乳酸菌环丙烷脂肪酸合酶基因的克隆及其在大肠杆菌中的表达

Cloning of Cyclopropane Fatty Acid Synthase Gene from Lactococcus Lactis and Expression in Escherichia Coli

酸提高绿茶提取物对脂肪酸合酶的抑制活性

Enhancement of Inhibitory Activity of Green Tea Extract on Fatty Acid Synthase by Hydrogen Ion

口腔鳞癌组织中脂肪酸合酶基因表达的实时定量研究

Quantitative detection of FAS gene expression in squamous cell carcinoma of the oral cavity by real-time polymerase chain reaction

50%乙醇的绿茶提取物具有抑制脂肪酸合酶和经口服降低大、小鼠体重的功能。

Treatment with 50 % ethanol extract of green tea inhibited this enzyme and reduced body weight of rats and mice upon oral administration .

在另一个独立的研究中她的研究团队确定了抑制脂肪酸合酶的具体的黄豆短肽，并已经明确了这过程是如何进行的。

In a separate study , her team identified specific soy peptides that inhibit fatty acid synthase , and they were able to learn exactly how it happens .

急性和慢性乙醇暴露对小鼠神经突触小体膜脂肪酸乙酯合酶活性的影响

Effects of acute and chronic ethanol exposure on fatty acid ethyl ester synthases in synaptosomal preparations from mice

利用MAS对差异表达表达基因进行GO分析，结果表明这些基因参与骨骼肌再生、横纹肌发育的正向调节、脂肪酸氧化、肌动蛋白丝结合以及脂肪酸合酶活性。

GO analysis of differentially expressed genes was performed by MAS . The result indicated these genes involved in skeletal muscle regeneration 、 positive regulation of striated muscle development 、 fatty acid oxidation 、 actin filament binding and fatty-acid synthase activity .

与脂肪酸合成和释放有关的重要的两个脂肪酶，分别是脂肪酸合酶（FASN）和脂蛋白脂酶（LPL）。

There are two important enzymes related with the synthesis and release of fatty acids , Fatty Acid Synthase ( FASN ) and Lipoprotein Lipase ( LPL ), respectively .

大豆种子脂肪酸合成主要发生在质体中，参与脂肪酸合成的酶主要为乙酰辅酶A羧化酶和脂肪酸合酶。

Fatty acid biosynthesis in soybean seed takes place in plastids . A number of enzymes are involved in this synthesis such as acetyl-CoA carboxylase ( ACCase ), fatty acid synthase complex ( FAS ) and etc.