肺炎链球菌

肺炎链球菌毒力蛋白DNA疫苗优势抗原组合筛选及鉴定

Screening of dominant antigen formats of DNA vaccine against Streptococcus pneumoniae

肺炎链球菌β-内酰胺酶TEM基因的发现

The discovery of TEM gene in isolated streptococcus pneumoniae

大鼠肺炎链球菌性脑膜炎脑组织明胶酶A、bmRNA的表达及活性分析

The mRNA expressions and activities of gelatinase-A and B in pneumococcal meningitis in rats

肺炎链球菌PCR定性及定量诊断方法的建立

Establishment of qualitative and quantitative methods of PCR product for diagnosis of Streptococcus pneumoniae

目的研究寡核苷酸探针和长链DNA探针在肺炎链球菌检测中的诊断价值。

Objective To study the diagnostic value of oligonucleotide probe and long-chain DNA probe in detection of Streptococcus pneumoniae ( SP ) .

目的对SD大鼠肺炎链球菌致病进行观察。

Objective : To observe the disease of SD rat caused by streptococcus pneumoniae .

结论成功地观察了SD大鼠肺炎链球菌致病的情况。

Conclusions : We have successfully observed the SD rat infected by streptococcus pneumoniae .

苏州地区肺炎链球菌TEM基因分子流行病学研究

Study on the molecular epidemiology of β - lactamase TEM gene in isolated Streptococcus pneumoniae

方法Etest法测定头孢地尼对肺炎链球菌等7种细菌共380株的最低抑菌浓度（MIC），并与头孢克洛作对比研究。

Methods MIC values of cefdinir against 380 strains were determined with E-test method and compared with those of cefaclor .

儿童呼吸道感染肺炎链球菌耐药性及pbp2B与TEM基因的研究

Antimicrobial resistance and penicillin resistance-associated genes of Streptococcus pneumoniae isolated from children with respiratory tract infection

在实验室检查方面，单纯Q热柯克斯体感染患者血小板计数明显较肺炎链球菌感染患者高（p<0.05）；

In experiment examination , purely Q fever infection patients have a higher blood platelets counts ( p < 0.05 ) .

肺炎链球菌的MIC药敏方法在全自动微生物系统的临床应用及评价

Application and Evaluation of Automated System MIC for Antimicrobial Susceptibility Testing of Streptococcus Pneumoniae in Clinical Laboratory

在CAP组患者中肺炎链球菌肺炎亚组与流感嗜血杆菌肺炎亚组之间MBL基因亚型分布也无显著差异。

This was also the case for CAP patients with pneumonia caused by Streptococcus pneumoniae or Haemophilus influenzae .

COPD急性加重期主要致病菌为金黄色葡萄球菌、肺炎链球菌、流感嗜血杆菌、卡他莫拉菌和铜绿假单胞菌。

Major pathogens in acute COPD include Staphylococcus aureus , Streptococcus pneumoniae , Hemophilus influenzae , Moraxella catarrhalis , and Pseudomonas aeruginosa .

肺炎链球菌在体外触发人肺Ⅱ型上皮细胞F-actin细胞骨架重排

Type ⅱ pneumocytes filamentous actin rearrangements induced by Streptococcus pneumoniae in vitro

苏州地区肺炎链球菌分离株tetM基因检测

Detection of tetracycline resistance tet M gene of isolated streptococcus pneumoniae strains in Suzhou area

制备肺炎链球菌感受态，首先在不同菌密度下转化外源DNA，计数抗生素筛选平板上的转化菌落，比较其转化率，确定转化的最适菌密度；

First exotic DNA was transformed under different cell density then the transformed colonies on antibiotic screening plate was counted to compare their transformation rate to ascertain the most suitable cell density for the transformation .

多重PCR方法检测标本结果为金黄色葡萄球菌3株，肺炎链球菌4株，流感嗜血杆菌7株，肺炎克雷白杆菌2株。

Multiplex PCR , the results of Haemophilus influenzae samples 7 strains , Streptococcus pneumoniae 4 strains , Staphylococcus aureus 3 strains , and Klebsiella pneumoniae 2 strains . Conclusion : 1 .

结论：1、荧光定量PCR作为一种快速的检测技术，其对肺炎链球菌检测的阳性率明显高于传统的培养方法；2、痰液在培养的检测方式中，对于肺炎链球菌的生长有影响。

Conclusions : 1.Fluorescence quantitative PCR , as a quick testing technology , its positive rate of bacterial detection is significant higher than traditional methods ; 2.Sputum itself has effect on the growth of streptococcus pneumoniae .

细菌构成谱与本地区成人CAP的基本相近，但肺炎链球菌所占比例远高于成人CAP患者。

The bacterial constitute about children with NP was essentially identical with the adult CAP of this area , but the proportion of streptococcus pneumonia was higher than that of the adults CAP patients .

基因comE、comX、cinA、dnaK在肺炎链球菌感受态形成中作用的研究

Research the Function of Gene comE 、 comX 、 cinA 、 dnaK in Competence of Streptococcus Pneumoniae

浙江地区青霉素耐药肺炎链球菌PBPs基因及氨基酸序列研究

Study on PBPs Genes of Penicillin-resistant Streptococcus pneumonia in Zhejiang Province

肺炎链球菌触发人肺Ⅱ型上皮细胞F-actin细胞骨架重排与TPK信号转导的相关性研究

Investigating on the relationship between F-actin rearrangements of type ⅱ pneumocytes induced by Streptococcus pneumoniae and TPK signal transduction in vitro

结论肺炎链球菌是儿童ALRI的常见病原。

Conclusion Streptococcus pneumoniae infection was common in children with ALRI .

结果聚合酶链反应分别扩增出263、351、370bp三种DNA探针，肺炎链球菌和流感嗜血杆菌只与其对应的探针杂交，细菌通用探针和病毒、真菌间无交叉反应。

Results The DNA probes of 263 , 351 , and 370 bp were amplified by PCR . Streptococcus pneumoniae and Haemophilus influenzae reacted only with their corresponding probes , and no cross reaction of the bacterial universal probe with virus and fungi was noted .

ClpE在肺炎链球菌致病过程中的作用机制研究

The Role of ClpE in the Pathopoiesis of Streptococcus Pneumoniae

clpE基因缺失对肺炎链球菌毒力的影响

Effect of clpE gene deletion on virulence of Streptococcus pneumoniae

对变形杆菌、卡他莫拉菌和肺炎链球菌，三者MIC90相近；

MIC90 of three antibiotics was similar against Proteus spp , Moraxella catarrhalis and Streptococcus pneumoniae .

肺炎链球菌comX基因可影响细菌毒力基因表达

Effect of comX gene on the expression of virulence genes in streptococcus pneumoniae

接种B型流感嗜血杆菌（Hib）和肺炎链球菌疫苗、有效的病例管理、提倡母乳喂养和补锌在降低肺炎死亡率上具有成本效益。

Vaccines against Hib and S.pneumoniae , efficacious case management , breastfeeding promotion and zinc supplementation are cost-effective in reducing pneumonia mortality .