肺移植
- 网络Lung transplantation;LTX
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结论BQ123对肺移植早期出现的缺血再灌注损伤具有保护作用。
Conclusion BQ123 plays a protective role in early IR injury after canine lung transplantation .
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1例同种异体单肺移植术病人术后在ICU期间的护理
Postoperative nursing care of an ICU case after underwent allogenic single lung transplantation
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做过心肺移植手术后,她的身体不断好转。
Since her heart and lung transplant operation she has gone from strength to strength
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前列腺素E1在心肺移植术中的应用
Applicaton of PGE_1 in Heart-Lung Transplantation
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胸部摄片、多排CT平扫、血气分析及病理检查证实成功建立大鼠原位单肺移植模型。
Thoracic X ray , Multi-slice CT scan , arterial blood gas analysis and pathological changes after transplantation manifested excellent graft function . 2 .
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大鼠肺移植术后早期肺组织ICAM-1表达的变化
Changes of ICAM-1 expression in transplanted lung at the early stage after rat pulmonary transplantation
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目的总结体外循环(CPB)在序贯式双肺移植中应用经验。
OBJECTIVE To summarize the clinical experience of cardiopulmonary bypass in bilateral sequential lung transplantation .
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方法以SD大鼠为供受体,采用改良袖套法技术建立同种异体左肺移植模型。
Methods A left lung transplantation formwork was constructed by using SD rat both donor and recipient by improved muff-like technique .
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肺移植术后受者T细胞亚群和IL-6水平的动态变化1例并文献分析
The Dynamic Changes of T Cell Subsets and IL-6 in Peripheral Blood of a Lung Allograft Recipient : a Case Report
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结果55例SD大鼠左肺移植成功,平均吻合时间为(36.2±9.6)min,手术成功率为91.7%。1周存活率为70.9%;
Results Transplants were performed in 55 rats ( 91.7 % ) and the mean time for anastomoses was ( 36.2 ± 9.6 ) min.
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大鼠肺移植急性排斥反应及FK506抑制作用的研究
Morphological Study of the Effect of FK506 on the Acute Rejection of Lung Transplants in Rats
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结论TBIL可以作为肺移植术后免疫抑制药物CSA肝毒性的敏感指标;
Conclusion TBIL is the sensitivity index of hepatotoxicity of immunity inhibitor CSA after lung transplantation .
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目的:观察肝移植及肺移植术后患者在ICU的监测治疗,总结其成功的经验。
Objective : To observe the monitoring and management of postoperative patients with liver and lung transplantation in ICU and summarize its successful experience .
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实验结果显示该模型成功复制出同种异体肺移植IRI的变化。
The experimental outcome demonstrated that the model could duplicated the change of the ischemia-reperfusion injury .
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作者报告并讨论了供受体选择,手术技术、术后管理,尤其是感染和免疫排斥反应的监测、鉴别及处理等关键性问题,强调HLA配型及经支气管镜活检对肺移植成功的重要性。
We discussed the selection of donors and recipients , operative procedures , postoperative manangement , especially monitoring , differential diagnosis and treatment of infection and rejection .
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方法:对30例大白鼠进行左侧单肺移植,利用透射电镜和病理学技术,检测移植肺、健侧肺及空白对照肺组织胀亡细胞,MDA及SOD活力。
Methods : Pulmonary transplantation was carried out with 30 rats . Cell oncosis , MDA , and SOD activity were detected by using transmission electron microscope and pathological techniques .
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结论COPD患者肺移植术后肺通气、气道阻力、残气、弥散、运动耐力及气体交换功能均明显改善。
Conclusion Spirometry , airway resistance , residual capacity , diffusion capacity , exercise tolerance and gas exchange were improved remarkably after lung transplantation in COPD patients .
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结论UTI对大鼠单肺移植模型中移植肺的缺血再灌注损伤有保护作用。
Conclusions This study demonstrated that ulinastatin prevented lung reperfusion injury after lung transplantation in this model .
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目的:探讨改良低钾右旋糖酐(LPD)溶液在心肺移植术中的肺保护作用。
Objective To determine the application of modified low-potassium dextran ( LPD ) solution in heart-lung transplantation .
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方法:选择同种异体犬肺移植术后存活的3个病例,用单克隆抗体-荧光偏振免疫法(MA-FPIA)测定其不同时期的CsA全血谷浓度。
Methods : We used MA FPIA to monitor the blood concentration of CsA for the 3 survival dogs with lung allograft transplantation .
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结论在心肺移植术中联合应用前列腺素E1及低温肺保护液肺动脉灌注具有良好的肺保护效果。
Conclusion The combination use of PGE 1 and modified LPD solution as the lung flush solution in heart-lung transplantation possessed a excellent protective effect for lung .
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采用兔异位心肺移植模型,在心肺转为自主功能状态后,连续观察3h。每30min测定移植肺的顺应性;
Using the hetero-heart-lung transplantation model , pulmonary graft function and airway compliance was assessed every 30 min for 3 h when the model was transformed into self-working state .
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目的:探讨兔肺移植中前列腺素A1(PGA1)在对供肺缺血再灌注损伤的保护作用及其可能的作用机制。
Objective : To investigate the protective effects of prostaglandin A1 ( PGA1 ) on ischemia-reperfusion during rabbit lung-transplant , and explore its possible mechanism .
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结果共完成26例大鼠肺移植手术,成功23例,失败3例,手术成功率为88.5%,术后7d存活率为100%。
Results In 26 cases of single lung transplantation in rats , the operation was successfully carried out in 23 cases and failed in 3 cases with the successful rate being 88.5 % .
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4例肝移植患者在ICU的平均滞留时间为60h,1例肺移植患者为110h。
The mean staying time in ICU of four liver transplantation patients was 60 hours , the staying time in ICU of one lung transplantation patient was 110 hours .
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手术由单人肉眼直视下完成,能基本模拟临床的肺移植过程,适合研究肺的IRI。
It can be completed under naked eye euthyphoria without the help of microsurgery . It is suit for application to study lung IRI for it can imitate clinical process of lung transplantation . 3 .
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同种异体犬肺移植后MA-FPIA法监测全血环孢菌素A浓度目的:观察环孢菌素A(CyclosporineA,CsA)在犬肺移植中不同时期的血浓度变化,以提高肺移植存活率。
Objective : Our aim was to monitor the blood concentration of cyclosporine A ( CsA ) in dogs with lung allograft by monoclonal antibody fluorescence polarization immunoassay ( MA FPIA ) in order to improve the survival rate of lung transplantation .
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研究目的:通过对Beagle犬施行单侧肺移植手术,掌握手术的基本步骤和要点,为后续实验打下坚实的基础,也为临床肺移植工作提供有价值的理论指导。
Research purposes : based on the Beagle dog single lung transplantation surgery , mastering the basic steps and main points , operation to lay a solid foundation for subsequent experiments , as well as clinical lung transplantation work provide valuable theoretical guidance .
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结论R-LPD液在肺移植冷缺血保存期中起较好的肺泡上皮细胞保护作用,比低钾右旋糖酐液(low-potassiumdextransolution,LPD液)具有明显的优越性。
Minimal interstitial and alveolar edema with interstitial macrophage infiltration was also observed . Conclusions R-LPD 'S exerts a cytoprotective effect on preservation of donor lung during pulmonary grafts , and it is superior to low-potassium dextran solution for this purpose .
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肺移植后缺血-再灌注导致的移植肺损伤有较高的发病率和致死率,所以有必要更好的理解LIRI的机制以及找到更有效的措施减轻再灌注损伤。
Reperfusion injury after lung transplantation continues to contribute to increased morbidity and mortality , so it is necessary to better understand the mechanisms of lung ischemia reperfusion injury and investigate one more reliable strategy to reduce the injury .