肺小叶

次级肺小叶的高分瓣CT与组织学对照研究

Correlative Study between High-resolution CT and Histologic Method of Secondary Pulmonary Lobule

正常肺小叶高分辨率CT研究

High-resolution Computed Tomography of Normal Secondary Pulmonary Lobule

其主要CT征象为：（1）肺小叶间隔的不均匀增厚；

The main findings were : ( 1 ) Extensive uneven thickening of the interlobular septa and fissures ;

HRCT见部分肺小叶实变、气肿、磨玻璃样改变；

HRCT scan images show that consolidation , emphysema or " ground glass " like changes occurred in some lung lobules .

结论：正常肺小叶结构可在HRCT图像上显示和辨认，肺小叶是肺脏放射学基本单位。

Conclusion : HRCT can detect secondary pulmonary lobules in normal subjects , which may be a basic anatomical unit in pulmonary imaging .

HRCT能清晰显示尘肺结节、肺小叶间隔增厚、各型肺气肿和大阴影等病变的特征。

But on HRCT the features including nodule , thicking of interlobular septal , pulmonary emphysema and large shadows were more clearly demonstrated in 25 cases .

170个肿块分叶中的150个大小在6～15mm之间，与肺小叶的大小相一致；

The lobulations were curved and 150 out of 170 lobulations were between 6 ~ 15mm in size , which simulated the pulmonary lobules .

结果表明：HRCT能显示正常次级肺小叶结构中的部分小叶间隔、小叶肺动脉，但不能在同一层面显示次级肺小叶的完整结构，不能显示核心结构中的终末细支气管。

The results showed that HRCT could display normal interlobular septa and lobular arteries in the lobular core of the fresh lungs , but not all of them at the same level . The normal terminal bronchioles were not visible in our investigation .

HRCT可显示肺小叶及其微细结构，显示叶间胸膜，可对粟粒点及网状结构进行详细分析获得更多信息，为DLD的诊断及鉴别诊断提供重要依据。

Pulmonary lobules patterns , its tiny structure and interlobular pleura can be showed apparently in HRCT , milliary changes and reticular patterns can also be analyzed individually . We obtained more information and more important basis in the diagnosis and differential diagnosis of DLD .

新生儿肺小叶的形态学观察

A Morphological study of Acini of Neonate Lungs

肺小叶间隔增厚；

Thickened pulmonary lobular septa ;

肿块分叶呈弧形，与肺小叶的形态相一致。结论：肺癌分叶形成的主要病理基础是小叶间隔内的纤维增生。

Conclusion : The major pathologic basis for lobulation of lung cancer is fibrotic hyperplasia within interlobular septa .

实变区域范围很接近肺小叶（因此又称小叶性肺炎）。

The consolidated areas here very closely match the pattern of lung lobules ( hence the term " lobular " pneumonia ) .

肺部高分辨率计算机断层发现在右上肺叶的后肺小叶有许多节结状浸润，且有厚壁空洞状的病灶。

A high resolution computed tomography of the chest showed multiple nodular infiltrations at the posterior segment of the right upper lobe with a thick-walled cavitary lesion .

弥漫肺间质、小叶改变5例；胸内肿块结节病灶4例；

Five cases were changed diffuse in pulmonary interstitial and lobule .

结果：腺癌肺转移具有肺小叶间隔增厚不光滑，有网状、串珠样改变。

Results : Through CT and HRCT analysis , the pulmonary metastatic tumor of adenocarcinoma had following features : lobular septa were thickened and not smooth , or reticular and beaded thickened .

结果：正常肺标本和活体肺小叶结构可被HRCT显示。

Results : The secondary Pulmonary lobules of normal lung speciman and individuals can be demonstrated by HRCT .

然而，小叶间隔、小叶肺动脉是HRCT图上认识次级肺小叶的标志。

However , these structures are the landmark to identify the secondary pulmonary lobule on HRCT images .

结果：①32例HAPE中28例右肺病变重于左肺，35例小叶性肺炎仅有14例（P<0.01）；

RESULTS : Twenty-eight of the 32 patients with HAPE demonstrated significant pathological changes in their right lungs while only 14 of the 35 patients with lobular pneumonia did ( P < 0.01 ) .

本文取新生儿肺20例，采用乳胶灌注制成塑型和组织切片的方法，在立体显微镜下对新生儿肺小叶的形态进行了比较系统的观察。

The morphology of the acini in the lungs from 20 newborn infants were studied by means of latex corrsion modelling method .