给药系统

例如，在靶向给药系统（targetingdrugdeliverysystem，TDDS）中，就要求药物载体&凝胶微球的粒径小，而且要求其具有较好的单分散性。

For example , in the targeting drug delivery system ( TDDS ), some cases require small diameter and good monodispersity of microsphere drug carrier .

综述了制备药物纤维的材料和技术以及药物纤维在新型给药系统（DDS）中的应用。

The raw materials and technologies for iatric fiber were reviewed , as was the application of iatric fiber in novel drug delivery system ( DDS ) .

靶向给药系统（targetingdrugdeliverysystem，TDDS）是第四代药物输送系统。

The fourth generation drug delivery system is targeting drug delivery system .

pH感应型给药系统的研究进展

Progress of pH-Responsive Drug Delivery Systems

前言：目的：介绍聚烯烃非PVC软包装输液给药系统。

Objective : Introduce non-PVC polyolefin soft-packing transfusion administration system .

有望作为pH敏感口服结肠定位给药系统药物载体。

The results imply that SBCS could be potential pH sensitive carrier for colon-specific drug delivery system .

一种新型给药系统&聚烯烃非PVC软包装输液

A Novel Type of Administration System & Non - PVC Polyolefin Soft - packing Transfusion

长春西汀透皮给药系统的设计与评价HPLC法测定卡莫司汀注射液的含量

Design and Evaluation of Vinpocetine Transdermal Delivery System ; HPLC assay for the related substances of carmustine

此外，选取合适的pH敏感高分子材料作为药物载体是设计和制备这种智能给药系统的另一关键。

Moreover , it is another key to choose a pH responsive polymer as drug carrier for this intelligent drug delivery system .

目的：制备pH依赖和时间双重控制的4-氨基水杨酸钠结肠定位给药系统，并考察其体外释药行为。

OBJECTIVE To prepare a new pH-dependent and time-controlled coated tablet for colon-specific targeting and to evaluate the drug release profile in vitro .

目的合成具有pH敏感降解性的新型载体聚丙烯酰氧肟酸酯，制备口服肠溶给药系统。

OBJECTIVE To synthesize polyacryl hydroxamic benzyl ester as the pH sensitive carrier , using its degradation properties to prepare enteric delivery system .

结论：聚烯烃非PVC软包装输液是一种很有前途的新型给药系统。

Conclusion : Non - PVC polyolefin soft - packing transfusion is a very promising novel type of administration system .

目的制备pH敏感的壳聚糖聚乙烯吡咯烷酮（PVP）水凝胶，作为甲硝唑治疗胃溃疡控释给药系统的载体。

OBJECTIVE To develop a pH-sensitive chitosan-polyvinyl pyrrolidone ( PVP ) based controlled drug release system for metronidazole delivery .

基于MonteCarlo模型的微型PLGA给药系统建模及仿真

Modeling and Simulation of the Drug Release from PLGA Drug Delivery Micro-system Based on Monte Carlo model

制备了基于壳聚糖和多羟基盐类化合物的凝胶给药系统，研究了其柱状凝胶和球状凝胶的制备以及其温度和pH双重感应性。

Hydrogel drug delivery systems based on chitosan / polyol salt combinations were prepared with cylindrical and spherical shapes , and their thermo - / pH-sensitivities were investigated .

免疫脂质体介导的eNOS基因给药系统在高胆固醇血症内皮细胞中的表达

Expression of eNOS gene delivery system mediated by immunoliposome in hypercholesterolemic endothelial cells

LHRH固体脂质纳米粒口服给药系统的研究

Study on LHRH-loaded solid lipid nanoparticles for oral administration

本课题为进一步研制LMWH口服给药系统奠定了理论基础和实验依据。

The study provided the theoretical foundation and experiment evidence for preparing oral drug delivery system of LMWH .

其结果为进一步研究DHE透皮给药系统提供了有益的参考。

The results were useful for further research of DHE transdermal delivery system .

VEGF、FGF-2低频超声透皮给药系统对猪超长筋膜瓣应用的初步研究

The Preliminary Study on the Application of VEGF and FGF-2 to Fascio-Cutaneous Flaps of Super Length in Pigs Via Low-Frequency Ultrasound-Mediated Transdermal Drug Transport System

葡聚糖磁性纳米复合微粒已被FDA批准作为MRI造影剂用于临床，并有望成为磁导靶向给药系统中理想的纳米载体。

The dextran magnetic composite nanoparticles ( DMNPs ) have been approved by FDA to be used as a MRI contrast agent in clinical and are expected to be an ideal carrier for magnetic drug delivery .

初步判断，DTX弹性脂质体微针给药系统具有一定程度的局部抗肿瘤作用。

These results demonstrated that DTX elastic liposomes-microneedle system could improve the local antitumor activity to some extent .

实验出血性休克家兔在电脑实时监测血压和自动给药系统（CAIMA）监控下，分别应用间羟胺（MET）、MET加多巴胺（DA）和MET加山莨菪碱（654－2）。

Metaraminol ( MET ), combined with either dopamine ( MET + DA ) or anisodamine ( MET + 654-2 ) were administered to hemorrhagic shock rabbits respectively under CAIMA ( computer assisted instant monitoring drug administration system ) .

以PEG-CLA为载体，采用透析法制备了紫杉醇聚合物胶束给药系统；

PEG-CLA polymer was employed as carrier , the paclitaxel-loaded micelles were prepared by dialysis method .

目的比较常用的两种报告基因β-Gal及GFP在大鼠多器官组织中的内源性表达及不同血脂水平下的变化，为构建基因靶向给药系统时报告基因的合理选择提供实验依据。

Objective To supply reference for selecting reporter gene which was used in gene target system , the variety of different lipid levels of the endogenous expression β - gal , GFP were compared in rats .

目的分析新制备的HER2靶向硼脂质体在细胞靶向、滞留及细胞内分布等方面的特性，探讨该脂质体作为靶向给药系统用于硼中子俘获治疗研究的可能性。

Objective To investigate HER-2 targeting boron liposomes as a potential drug delivery vehicle for boron neutron capture therapy , in respect to cellular uptake , retention and the subcellular location .

一种相关的神经靶向给药系统载体NG2在临床前动物试验中被证实可以降低神经损害和糖尿病引起的神经性疼痛。

A related NTDDS vector , NG2 reduces pain-related behaviors in preclinical models of neuropathic pain from nerve injury and diabetes .

本课题以CSO-SA胶束为基本材料，考察其在脑靶向给药系统上应用的潜能。

In this research , the potential of CSO-SA on brain targeting drug delivery is studied .

本研究为改善环孢素A生物利用度提出新的思路和有效手段，为开发抑制P-gp新型环孢素A给药系统建立理论基础。

The results of present studies provided a new idea and a useful method for improving poor bioavailability of CsA , and established theoretical basis for developing new CsA drug delivery system by inhibition of P-gp .

上述研究结果表明DTX弹性脂质体微针给药系统在改善DTX经皮渗透性上具有显著优势，具有潜在应用价值。

The results above showed that combining DTX elastic liposomes with microneedle pretreatment significantly improved the skin delivery of DTX , and showed great potential application value .