类肝素

类肝素化抗凝血材料的研究&PVA，PET及PEU的磺化反应及血液相容性

Study on Heparin like Materials & Sulfonization and Blood Compatibility of PVA , PET and PEU

补肾安胎方对胚泡着床障碍小鼠子宫内膜微环境和类肝素结合因子（HB-EGF）表达的影响

Effect of indomethacin recipe on the endometrial LIF expression in the mouse with blastocyst implantation on dysfunction

对于急性缺血性卒中患者，推荐不用全量抗凝，静脉输注或皮下注射低分子量肝素或类肝素（1B级）。

For patients with acute ischemic stroke , we recommend against full-dose anticoagulation with IV , SC , or LMWHs or heparinoids ( Grade1B ) .

该物质有机硫含量为20%，凝胶色谱显示其相对分子质量为3000～4000，红外光谱和1H核磁共振光谱表征其具有类肝素的结构。

Its sulfur content was 20.0 % . Its molecular weight was 3000 ~ 4000u by GPC . The results of IR and 1H NMR spectrometry showed that it possessed the structure of heparinoids .

目的：观察中药补肾安胎方对胚泡着床障碍模型小鼠胚泡着床、子宫内膜形态学影响以及对类肝素结合因子（HB-EGF）表达的影响.方法：采用吲哚美辛引起的胚泡着床障碍动物模型；

Objective : To observe the effect of indomethacin recipe on the endometrial HB-EGF expression in the mouse with blastocyst implantation on dysfunction ( EID ) .

目的：观察类肝素药物喜疗妥软膏（Hirudoid）对深°烧伤创面愈合的作用。

Objective : The effect of heparinoid hirudoid cream ( hirudoid , Sankyo Pharma GmbH , Germany ) for wound healing of deep 2nd degree burn was investigated .

以新型类肝素聚阴离子磺化羟丙基壳聚糖（HPCSS）为净化剂，研究其选择净化血液低密度脂蛋白（LDL）及纤维蛋白原（Fib）的性能。

The selective removal of low density lipoproteins ( LDL ) and fibrinogen ( Fib ) by novel heparin like material & hydroxylpropyl chitosan sulfate ( HPCSS ) was studied .

Glypican-3（GPC3）为膜性硫酸乙酰肝素多糖蛋白，通过糖基磷脂酰肌醇（GPI）结合于细胞表面，是硫酸类肝素糖蛋白聚糖（glypican）家族成员。

Glypican-3 ( GPC3 ) is a heparan sulfate proteoglycan that is bound to the cell membrane by a glycosylphosphatidylinositol ( GPI ) anchor , which is a member of Glypicans family .

一种新型类肝素吸附剂的试制

Preliminary Study on the Preparation of a Novel Heparin like Adsorbent

类肝素酶-1和血管内皮生长因子在嗜铬细胞瘤中的表达及其相关性

Expression and correlation of Heparanase-1 and vascular endothelial growth factor in pheochromocytomas

类肝素酶在胃癌组织中的表达及其临床价值

Expression of heparanase in gastric cancer and its clinical value

猪十二指肠类肝素对实验性动脉粥样硬化形成的影响

Effect of heparinoid extracted from pig duodenum on experimental atherosclerosis formation in quails

肝素/硫酸类肝素与蛋白质的相互作用

Heparin Interaction between heparin / heparan sulfate and protein

猪十二指肠类肝素抗血管内膜增生的研究

Effect of heparinoid extracted from porcine duodenum on the experimental vascular intima hyperplasia in rats

类肝素结合性表皮生长因子在人子宫内膜植入窗期的表达和意义

Expression and significance of heparin-binding epidermal growth factor in human implantation window phase of endometrium

新型类肝素物质的研究（I）&磺化羟丙基壳聚糖凝胶的研制

Study on the Preparation of Novel Heparin-Like Materials ( I ) ─ Hydroxylpropyl Chitosan-Gel Sulfate

抗凝血活性是肝素或类肝素物质使用前的重要检测指标。

It is quite important to evaluate anticoagulant activities of heparin or heparin-like agents before their applications .

碱提类肝素组分Ⅱ对鹌鹑血清及动脉壁胆固醇的影响

The effect of heparinoid fraction ⅱ of basic extraction on serum and arterial wall cholesterol in quail

深Ⅱ°烧伤创面早期应用类肝素药物的临床观察

Clinical observation of the therapeutic effect of hirudoid on the deep 2nd degree burn wound at the early stage

类肝素、阿司匹林、氯沙坦联合应用抗实验性血管内膜增生的研究

Effects of combined use of heparinoid , aspirin , and losartan on the experimental vascular intima hyperplasia in rats

碱提类肝素对大鼠血浆脂质的调整作用及机理

Studies of effects on heparinoid extracted by alkaline craft and its fraction-one , fraction-two on serum lipids in rats

硫酸类肝素是一种结构十分复杂，承担着多种独特生物功能的糖胺聚糖。

Heparan sulfate is a typical kind of glycosaminoglycan ( GAG ), having complex structures and charged with many particular biological activities .

结果表明，壳聚糖类肝素化合物的抗凝血性能是由甲壳糖主链上引入的-COOH和-SO3H两种基团的协同效应产生的，血液相溶性的优劣主要取决于-COOH和-SO3H两者的比例。

Results showed that the blood compatibility properties of heparin-like compounds of chitosan were simultaneously affected by both-COOH and-SO3H in the main chains of chitosan .

综述了近年来有关类肝素寡糖以及壳聚糖、透明质酸、软骨素等硫酸/磺酸化衍生物抗凝血性的研究进展；

The latest progress in anticoagulation of heparin-like oligosaccharides and of chitosan - , hyaluronic acid - and chondroitin-sulfated / sulfonated polysaccharide derivatives is reviewed .

本研究重点观察苦瓜对链脲霉素诱导的糖尿病大鼠肾脏硫酸类肝素的调节作用。

In the present investigation , effect of bitter gourd on streptozotocin-induced diabetic rats with particular emphasis on kidney heparan sulfate ( HS ) was studied .

类肝素超支化聚醚的制备、组装及其生物相容性的研究其中一类的干扰素（尔法）常被用来治疗乙肝或丙肝感染。

SYNTHESIS AND SELF-ASSEMBLY OF SULFONATED HYPERBRANCHED POLYETHERS AND THEIR BIOCOMPATIBILITY One class of interferons ( alpha ) is used to treat chronic infection with HBV and HCV .

中国国家药监局重申了自己的立场，称没有证据表明，美国患者的死亡与药品中发现的“类肝素物质”存在直接关联。

The SFDA reiterated its position that there was no proven link between the deaths in the US of patients and " a heparin-like substance " found in the drug .

制备了一类可生物降解肝素钠两性壳聚糖复合物（HPACS），并探索将其用于蛋白药物pH响应释放。

A series of biodegradable heparin / ampholytic chitosan ( HP / ACS ) complexes were developed for pH-sensitive release of protein drugs .

他汀类与低分子肝素钙治疗急性冠脉综合征临床疗效观察

Observation of Clinical Therapeutic Effect of Statin and Heparin Calcium of Low Molecular for Acute Coronary Syndrome