门控离子通道

并且大量研究结果发现，神经系统中，部分甾体激素类物质可以直接作用于一些细胞膜表面配体门控离子通道或G蛋白偶联受体，从而在数毫秒至数秒内即可改变神经元兴奋性。

Considerable evidence has emerged that , during a millisecond to second time window , some steroids alter neuronal excitability via the cell surface through the interaction with specific neurotransmitter receptors or G-protein coupled receptors .

环核苷酸门控离子通道（cyclicnucleotide-gatedionchannels，CNG）是非选择性的阳离子通道，直接被环核苷酸活化。

Cyclic nucleotide-gated ion channels ( CNGs ) are nonselective cation channels and opened by the direct binding of cyclic nucleotides , cyclic GMP and cyclic AMP .

NMDA受体是兴奋性氨基酸谷氨酸（Glu）的特异性受体，属配体门控离子通道，是由不同的亚单位组成。

The NMDA ( N methyl D aspartate ) receptor is a ligand gated subtype of ionotropic glutamate receptors , comprising different subunits .

P2受体可再分为两类，即配体门控离子通道型受体（P2X受体）和G蛋白偶联型受体（P2Y受体）。分子生物学研究结果显示：P2X受体包括七种亚型，即P2X1～7；

The P2 receptors are divided into two categories : the ligand-gated ion channel receptors ( P2X ) and the G protein-coupled receptors ( P2Y ) .

环核苷酸门控离子通道的结构、功能及活性调节

Molecular Structures , Physiological Roles and Regulatory Mechanisms of Cyclic Nucleotide-gated Ion Channels

DICE：电压门控离子通道电生理实验数据库

DICE : Database of Ion Channel Electrophysiology

甘氨酸受体属于配体门控离子通道超家族。

The glycine receptor channels ( GlyRs ) belong to the ligand-gated ion channel superfamily .

味觉感受细胞膜上存在多种电压门控离子通道。

There are several types of voltage-gated ion channels on the membrane of taste receptor cells .

突触后膜上化学门控离子通道的开放比例与突触前膜电位呈正相关；

And the opening proportion of chemical-gated ion channels on postsynaptic membrane was positively related to the potential of presynaptic membrane .

研究了神经递质以泊松点序列释放和电压门控离子通道噪声共同作用下线性整合放电模型的相干共振现象。

The CR phenomenon of a linear integral-and-fire model subject to a neurotransmitter Poisson point trains and a voltage-gated noise is investigated .

文章综述了环核苷酸门控离子通道的类型、功能、研究方法及其与疾病的关系。

This paper summarized the type and function and method of research and the relation with disease of cyclic nucleotide-gated ion channels .

P2X7受体是ATP门控的离子通道，对二价阳离子有较强的选择性。

P2X_7 receptor is an ATP-gated cation channel which has strong selectivity for the divalent cations .

目的：内脏高敏感性是肠易激综合征（IBS）的重要病理生理学机制之一，本文研究电压门控钠离子通道与内脏高敏感性之间的关系以进一步了解IBS的发病机制。

Objective To determine whether the voltage-gated sodium channels ( VGSC ) are involved in the visceral hypersensitivity of irritable bowel syndrome ( IBS ) .

研究结论：1.钙离子通过电压门控钙离子通道和以及钙离子激活的钾离子通道，对FCM模型的放电活动及动作电位波形产生影响。

Through voltage control calcium channels and the calcium activated potassium channels , calcium ions have an influence on the firing and the shape of action potentials in FCM model .

用制霉菌素穿孔膜片钳方法研究5－HT和NA对急性分离的大鼠骶髓后连合核神经元甘氨酸门控氯离子通道电流（IGly）的调控作用及其胞内机制。

The effects of 5 HT and NA on glycine gated Cl - channel currents ( I Gly ) and its intracellular mechanisms were investigated in acutely dissociated rat sacral dorsal commissural neurons by using nystatin perforated patch clamp recording .

体外培养视网膜神经元电压门控钾离子通道特性的研究

Electrophysiological Properties of Voltage-gated Potassium Channels of Cultured Newborn Bovine Retinal Neurons

抑制性谷氨酸门控氯离子通道胞外域的原核表达及纯化研究

Prokaryotic Expression and Purification of Extracellular Domain of Inhibitory Glutamate-Gated Chloride Ion Channel

白细胞介素1β对大鼠海马神经元电压门控钠离子通道的影响

Effects of Interleukin-1 β on Voltage Gated Sodium Channel of Acutely Isolated Rat Hippocampal Neurons

电压门控钠离子通道在大鼠肠易激综合征模型中的变化

Study on the changes of the voltage-gated sodium channels in the irritable bowel syndrome rat model

我们实验组前期的研究表明该复合体的功能抑制对于电压门控钠离子通道的功能会产生调控作用。

Our previous work showed that the inhibition of complex III exerted regulatory effect on the voltage-gated sodium channel .

培养心肌细胞感染病毒后电压门控钾离子通道表达的改变及芦丁作用的研究

Study on the Expression of the Voltage-gated Potassium Channels in Virus-infected Cultured Newborn Rat Ventricular Cells and the Effect of the Rutin

目的探讨体外培养不同时期新生小牛视网膜神经元电压门控钾离子通道的特性。

The characterizations of voltage-activated potassium channels were studied on newborn bovine retinal neurons in long-term cultures with whole-cell patch clamp technique .

目的：通过观察胍丁胺对大鼠海马神经元电压门控性离子通道的影响来探讨其作用机制。

AIM : To investigate the mechanism of agmatine by observing the effect of agmatine on the voltage-gated channels in rat hippocampal neurons .

这种结构与电压门控Na+/Ca2+离子通道的第4个跨膜片段的结构和性质相似，提示含有这个片段的蛋白可能是被电压调控的。

This structure is similar to segment 4 of voltage-dependent Na + / Ca2 + channels , indicating that it is probably voltage-dependent .

随着配体门控型离子通道分子克隆研究技术的发展，对由特定亚单位组成的重组受体的药理学研究成为可能。

Molecular cloning of cDNAs coding for ligand-gated ion channel subunits makes it possible to study the pharmacology of recombinant receptors with defined subunit compositions .

结果表明，在采集电压门控性离子通道电流时，合理地利用P/N漏减会使离子电流记录更为准确可靠。

Our results indicate that voltage-gated ion channel currents recorded by Clampex will be more accurate and reproducible by properly using P / N leak subtraction .

探讨氨基酸受体门控性离子通道电流改变在肝性脑病（HE）发生中的作用。

Objective To explore the effects of the changes of the amino acid receptor gated ion channel currents on the pathogenesis of hepatic encephalopathy ( HE ) .

其离子型受体是一类重要的配体门控性离子通道。此外，神经细胞上还存在不同类型的电压依赖性钙通道。

The ionotropic glutamate receptor ( iGluR ) is one of the typical ligand-gated ion channels . In addition , there are several various VDCC in neuronal cells .

囊性纤维化跨膜传导调节因子（CFTR）是一种cAMP激活的ATP门控性氯离子通道，表达于气道，消化道和生殖道上皮细胞的顶部质膜中。

The cystic fibrosis transmembrane conductance regulator ( CFTR ) is a cAMP-activated and ATP-gated Cl ~ - channel expressed in the apical plasma membrane of epithelial cells in the airways , digestive and reproductive tracts .

辣椒素通过钙信号抑制感觉神经元的电压门控性钙离子通道

Capsaicin inhibits voltage-activated calcium channel via calcium signals in sensory neurons