米索前列醇

阴道内置米索前列醇600μg和800μg治疗早期流产

Intravaginal misoprostol 600 μ g and 800 μ g for the treatment of early pregnancy failure

目的观察25μg米索前列醇对晚期妊娠引产的有效性和安全性。

Objective To determine the efficacy and safety of 25 μ g misoprostol for labor induction in the third trimester of pregnancy .

结果米索前列醇用于足月妊娠引产的有效率为94.3%，显著高于催产素组78.3%（P＜0.01）；

Result The effective rate of induction labor was 94.3 % , 78.3 % in misoprostol group and oxytocin group , respectively .

观察组：100例术前1～2小时阴道后穹窿放置米索前列醇200μg；

Observation group 100 cases misoprofil 200 μ g were put at the back of vagina 1 ~ 2 hours before operation .

结论：在终止早期妊娠的负压吸引术前口服或阴道放置米索前列醇400μg，均能有效扩张宫颈。

Conclusion : Oral misoprostol 400 microgram and vaginal misoprostol 400 microgram were similarly effective for cervical dilatation in the early pregnancy interruption .

提示：米索前列醇用于足月妊娠引产，每次于阴道后穹隆放置50～75μg，是一安全有效的引产方法。

The induced labor of the term pregnancy with misoprostol 50-70 μ g inserted into vaginal posterior fornix was a safe and effective method .

研究组800例，在第二产程胎头娩出后即口服米索前列醇600μg；

For the study group , 600 μ g of misoprostol was given orally after delivery of fetal head at the end of the second stage .

结论：术前1～2小时阴道后穹隆放置米索前列醇200μg可起到扩张宫颈，提高手术质量，减少手术并发症效果。

Conclusion : It could be easier cervical dilatation , improving operation quality and less side-effect to administer 200 μ gmisoprostol 1-2 hours before the operation .

米索前列醇阴道给药与催产素浓缩液和PGE2阴道给药对妊娠中期引产作用的比较

Vaginal misoprostol versus concentrated oxytocin and vaginal PGE2 for second-trimester labor induction

结果米索前列醇组引产组引产成功率显著高于缩宫素组（P0.01）；

Results : Compared with oxytocin group , the effective rate of using misoprostol for labor induction was significantly higher ( P0.01 );

随机对照试验比较应用米非司酮6～8h与24h后加用米索前列醇治疗流产的疗效

A randomized comparison of misoprostol 6 to 8 hours versus 24 hours after mifepristone for abortion

375例早孕妇女，分组用po米非司酮片单用或合用米索前列醇片，观察其终止早孕的临床疗效。

375 early pregnancy cases accepted mifepristone tablet and / or misoprostol tablet in groups at different methods and doses .

结果术中及术后2小时内平均出血量，米索前列醇组为（232.0±46.6）ml，催产素组为（385.0±74.7）ml。

Results The mean amount of bleeding was ( 232.0 ± 46.6 ) ml in misoprostol group and ( 385.0 ± 74.7 ) ml in oxytocin group respectively .

目的：探讨米非司酮配伍米索前列醇（米索）中止早孕后对再次妊娠早孕蜕膜雌激素受体（ER）、孕激素受体（PR）的影响。

Objective : To investigate the effects of mifepristone in combination with misoprostol on estradiol and progesterone receptors in decidua after terminating early pregnancy again .

方法选择需行宫腔镜电切手术患者96例，分为两组：米索前列醇组48例，患者行宫腔镜手术前3h阴道放置米索前列醇400μg；

[ Methods ] 96 women before hysteroscopy were divided into two groups . 48 case were divided into misoprostol group which with vaginal misoprostol 400 μ g.

目的：探讨米索前列醇（简称米索）用于足月妊娠引产对产妇血清雌二醇（E2）和孕酮（P）水平的影响。

Objective : To explore the effects of Misoprostol on serum estradiol ( E_2 ) and progesterone ( P ) concentrations in the parturients on induced labor for full term pregnancy .

d3每2h给予米索前列醇片200μg，最大累积剂量1000μg。

At the third day , they were treated with misoprostol vaginal tablet 200 μ g / 2h , with a maximal cumulative dose of 1000 μ g.

治疗组手术后30min内直肠置入米索前列醇200μg，对照组臀部肌肉注射缩宫素20U，观察两组术中及术后的出血量。

Misoprostol was given through the rectum approach in the study group within 30 minutes after delivery .

结论800ug/d和低剂量的米索前列醇都能够预防NSAIDs所致的消化性溃疡。

Conclusion Both 800 ug / d and low dose of Misoprostol can prevent the NSAIDS-induced ulcer .

应用子宫内压力测定方法研究米索前列醇（Mis）对早孕、晚孕和产后大鼠在位子宫收缩活动的影响。

Effects of misoprostol ( Mis , 30-1000 g / kg ) on uterine contraction of the anesthetized early , late-pregnant and postpartum rats were studied by measuring intra-uterine pressure .

目的探讨米索前列醇（misoprostol）在绝经后妇女取环中的临床应用价值。

Objective To study the value of the clinical application of Misoprostol to the removal of intrauterine devices for menopausal women .

结果：米非司酮合并米索前列醇在引产成功率、所需时间、有无残留及产后出血量等方面优于利凡诺组（P值均<0.05）。

Our results showed that in the experimental group , better results were achieved in terms of success rate in induced labor , treatment period required , remnant of placenta and membrane and puerperal hemorrhage as compared with controls ( P < 0.05 ) .

目的：比较奥美拉唑（omeprazole，Ome）、铝碳酸镁（Talcid，Tal）和米索前列醇（misoprostol，Mis）对急性胃粘膜损伤的保护作用及机制。

AIM : To investigate the protective effect of antiulcer agents omeprazole , misoprostol and Talcid on the acute gastric mucosa lesion .

一种可能的选择是米索前列醇的标示外使用，这是一种合成的前列腺素E1类似物，被核准用于防止和治疗胃肠道溃疡。

One possible option in this setting is the off-label use of misoprostol , a synthetic prostaglandin E1 analogue licensed for prevention and treatment of gastrointestinal ulcers .

于第妊娠7d，除正常组外，其余各组采用米非司酮配伍米索前列醇复制不完全药物流产模型。

At the seventh day of pregnancy , except for the normal group , every groups were induced incompletely abortion model by mifepristone compatibility misoprostol .

观察组46例，于切开腹部皮下脂肪后即由专人将1粒米索前列醇片（200μg）置于孕妇舌下，待胎儿娩出后，宫体肌注催产素20U。

43 cases of the observation group had the following treatment . After abdominal subcutaneous fat was opened , one misoprostol tablet ( 200 μ g ) was placed under sublingual .

目的：对氨甲喋呤（MTX）合并米非司酮与米索前列醇（米索）抗早孕的剂量、副作用作一初步探讨。

Objective : 182 cases of early pregnant women were treated with oral lowdose MTX combined with mifepristone and misoprostol in order to observe the effect of termination of early pregnancy .

Ganesh说米索前列醇可能被一些家庭用来强迫妇女选择性地流产女性胎儿。

Ganesh says misprostol could be used by families to coerce women into selectively aborting female fetuses .

A组：术前4h阴道后穹隆放置米索前列醇200μg，然后异丙酚静脉麻醉下进行人工流产手术。

Group A : Misoprostol was set at the back arched roof of the vagina at the 4h before operation with a dosage of 200 μ g , followed with anesthesia for induced abortion by intravenous injection of Propofol .

米非司酮加米索前列醇配伍PG05终止剖宫产2年内早孕的临床观察

Clinical Observation of Mifepristone Plus Misoprostol Combined PG05 for Termination of Early Pregnancy after Cesarean Within two Years