皮肤刺激

FDA发布经皮仿制药对皮肤刺激性和过敏性临床试验的设计及评分系统

Designs and scoring systems of FDA issue to skin irritation and sensitization clinical trial of generic transdermal drugs

家兔皮肤刺激性实验结果表明，DTX弹性脂质体可降低DTX对皮肤的刺激性。

Skin irritation test in rabbits showed that the DTX elastic liposomes can decrease the irritation of DTX to the skin .

使用对皮肤刺激性不强的肥皂。

Use a soap that is mild on the skin .

皮肤刺激性试验表明：CMF对皮肤无致敏性。

Skin test indicated that CMF has no cutaneous anaphylaxis .

负压伤口贴的样品检测包括：性状、尺寸、负压值、pH值、耐热试验、耐寒试验及皮肤刺激试验。

The sample tests of negative pressure wound glue include : character , size , the value of negative pressure , pH value , heat resistance test , cold test and skin stimulation test .

方法采用运动疗法、ADL训练及皮肤刺激对94例脑卒中偏瘫患者进行6-12个月治疗。

Methods By using motortherapy , ADL training and skin stimulation , 94 stroke patients with hemiplegia received treatment for 6 to 12 months .

结果：酸枣仁油对大小鼠均未测出LD50，家兔皮肤刺激实验未见急性毒性反应。

RESULTS : We did not get LD50 to mouse and rat , and no chronic toxicity to rabbit skin .

方法：根据ISO标准，采用急性全身毒性试验、溶血试验、细胞毒性试验、皮肤刺激试验和口腔粘膜刺激试验对玻璃陶瓷进行评估。

Methods : five tests were taken up according to ISO standards including acute systemic toxicity test , hemolysis test , cytotoxicity test , dermal stimulation test and oral mucosal membrane stimulation test .

方法首先将含羟基磷灰石生物陶瓷进行毒性试验，包括全身毒性试验、皮肤刺激试验、溶血试验、Ames试验及细胞毒性试验。

Methods First , HA-contain bioceramic toxic tests including generalized toxic test , skin stimulation test , hemolytic test , Ames test and cytotoxic test were carried out .

硝酸士的宁对鲫鱼皮肤刺激诱发Mauthner细胞电位的影响

Strychnine nitrate ' Effect on intracellular potentials of mauthner cell evoked by skin stimulation in the crucian carps

家兔皮肤刺激性试验结果表明，ATPs对完好皮肤无刺激性，对破损皮肤具有轻度刺激；豚鼠过敏性试验结果显示ATPs无致敏性。

The results of rabbit skin irritation test and Guinea pig skin allergia test make it certain that ATPs is safe for topical administration .

其原液对小鼠口服LD50＞5000mg／kg，对家兔皮肤刺激反应积分为0，属实际无毒、无刺激物质。

The oral LD 50 of its stock solution in mice was 500 mg / kg and the integrated score of skin irritative reaction in rabbits was zero , therefore it belongs to actually non-toxic and non-irritative substance .

皮肤刺激和过敏试验以及临床应用表明CHMA医用广谱抗菌耐洗涤织物可供人体安全使用。

The testing of skin irritation and allergic reaction together with clinical practice show that the CHMA fab-rics are safe enough to human body .

毒性试验表明，小鼠口服LD50＞5000mg／kg，对家兔急性皮肤刺激未见红斑与水肿，小鼠骨髓微核试验阴性。

Toxicity test indicated that its oral LD50 was > 5000 mg / kg in mice , no erythema and edema were induced by its acute skin stimulation in rabbits and bone marrow micronucleus test was negative in mice .

方法采用壳聚糖为主要辅料制备涂膜剂，用二喹啉甲酸试剂盒测定制剂中重组干扰素α1b的含量，考察制剂的稳定性，并进行皮肤刺激性试验。

METHODS : The plastics was prepared with chitosan as the main excipients , the content of INF α 1b was de-termined by di-quinoline methanoic acid kit , the stability of the plastics was determined and its skin irritation test was con-ducted .

新西兰大耳白兔10只背部脱毛，每只形成3个分开的相同大小随机实验区，作为SGS、MT-SGS和空白对照，观察原发性皮肤刺激实验。

10 New Zealand white rabbits were depilated in back , randomly formed three same size segregate zones ( the control zone , SGS zone , MT-SGS zone ) and observed primarily cutaneous stimulation .

毒性试验表明，该消毒剂对雌、雄性小鼠口服LD50＞5.0g／kg，对豚鼠皮肤刺激反应积分为0，小鼠骨髓红细胞微核试验为阴性。

Toxicity test showed that its oral LD50 in female and male mice was > 5.0 g / kg . The integral of irritative reaction of guinea & pig skin to it was zero . Mouse bone marrow erythrocyte micronucleus test was negative .

哥伦比亚大学教授、《重置你的生物钟》一书的作者、心理学家Dr.MichaelTerman通过email告诉赫芬顿邮报，这项新研究说明：阳光能有抗抑郁的效果，是因为紫外线照射皮肤刺激了维生素D的产出。

Psychologist Dr. Michael Terman , professor at Columbia University and author of the book " Reset Your Inner Clock , " told The Huffington Post in an email that this new research implies the antidepressant benefit comes from exposure to ultraviolet rays that act on the skin to stimulate vitamin D production 。

AMX-LH-NE的安全性评价通过急性毒性试验、皮肤刺激性试验和乳腺上皮细胞毒性试验，对AMX-LH-NE进行体内外安全性评价。

Safety evaluation of AMX-LH-NEThe safety of AMX-LH-NE was evaluated in vivo and in vitro by acute toxicity test , skin irritation test and cytotoxic test of mammary epithelial cells .

方法按GB15670-1995农药登记毒理学试验方法对5种有机锡农药进行急性经口、经皮毒性试验，家兔眼刺激试验及家兔急性皮肤刺激试验。

Five kinds of organotin pesticide were tested by conducting oral toxicity test and acute dermal toxicity test on rats , skin irritation test and eye irritation test were also conducted according to the regulation of GB 15670-1995 methods for pesticide register toxicity test .

眼及皮肤刺激试验均为轻度刺激性。

Light irritation to skin and eyes for rabbits was obserbed ;

治疗过程中未发现爽肤巾组有皮肤刺激等不良反应。

No skin irritant reaction and other adverse reactions were found .

结果一次皮肤刺激试验受试皮肤的最高皮肤刺激指数为0.25；

[ Results ] The highest skin irritation index was 0.25 ;

癌痛宁巴布剂皮肤刺激性和致敏试验

Experimental Study on Skin Irritation and Allergia of Ai-tong Ning Plaster

制剂质量稳定，无明显的皮肤刺激性。

The preparation had stable quality , no significant skin irritation .

冷烫液皮肤刺激性和致敏性试验研究

Observation on test of the stimulus and sensitivity of cold wave

尼莫地平贴剂体外渗透性及皮肤刺激性考察

The Observation on in vitro Permeation and Irritation of Nimodipine Patches

8-甲氧补骨脂素乳膏皮肤刺激性和致敏性实验研究

Experimental study on the cutaneous irritation and sensitization of 8-methoxypsoralen cream

结果类人胶原蛋白的急性毒性试验、溶血试验、热原试验、皮肤刺激试验均为阴性。

Results Human-like collagen presented negative results in those tests .

抗菌整理布杀菌效果及对皮肤刺激性试验观察

Experimental observation on germicidal efficacy and skin irritation of antibacterial finished cloth