甲状腺乳头状癌

[结论]（1）CK19和P53是甲状腺乳头状癌病理诊断中非常有价值的辅助诊断指标。

[ Conclusions ] ( 1 ) CK19 and P53 are valuable assistant diagnostic points for PTC pathological diagnosis .

P53、PCNA、E&cad基因的表达反映了甲状腺乳头状癌恶性表型的某些特点，在临床上其检测可作为诊断，治疗的参考指标。

The alteration of p53 、 PCNA and E & cad may reflect some malignant biology of PTC , and use as a molecular index for clinical diagnosis and therapy .

HT合并甲状腺乳头状癌2例，合并B细胞淋巴瘤1例。

Two cases of HT were complicated with thyroid papillary cancer .

癌胚胎纤维连接蛋白mRNA在甲状腺乳头状癌中的表达

Expression of Oncofetal Fibronectin mRNA in Thyroid Papillary Carcinoma

血型抗原LewisA和Lewisx在甲状腺乳头状癌中的表达

Expression of Lewis A and Lewis X in Thyroid Papillary Carcinoma

结果甲状腺乳头状癌中存在P53和VEGF的过度表达；

Results Papillary carcinoma was existence of over-expression of P53 and VEGF ;

甲状腺乳头状癌中组织蛋白酶bmRNA的阳性表达率明显高于正常甲状腺组织（P＜0.05）。

The positive rate of cathepsin B mRNA has a significant difference between papillary thyroid carcinoma and normal thyroid tissue ( P0.05 ) .

结论：甲状腺乳头状癌预后可能与p53蛋白过度表达有关。

Conclusion : The expression of p53 protein may relate the prognosis of thyroid papillary adenocarcinoma .

原癌基因c-fos在Graves'病和甲状腺乳头状癌中表达的研究

Study on oncogene c-fos expression in Graves'disease and thyroid papillary carcinoma

甲状腺乳头状癌中HIF-1α、VEGF表达与血管生成的关系

Correlation of HIF-1 α and VEGF Expression with the Angiogenesis of Papillary Thyroid Carcinoma

NF-kB和MMP-9在甲状腺乳头状癌中的表达及意义

Expression and Significance of NF-kB and MMP-9 in Thyroid Papillary Carcinoma

目的探讨抑癌基因P53和血管内皮生长因子（VEGF）在甲状腺乳头状癌发生、发展中的作用。

Objective To observe tumor suppressor gene P53 and vascular endothelial growth factor ( VEGF ) in papillary thyroid cancer .

目的阐明甲状腺乳头状癌（Papillarythyroidcarcinoma，PTC）组织学变型的临床生物学特点。

Objective To identify the clinical biological characteristic difference in the histological variants of papillary thyroid carcinoma ( PTC ) .

应用基因芯片技术对Graves病、甲状腺乳头状癌相关基因表达的研究

Study on Differentially Expressed Genes in Graves Disease and Papillary Thyroid Carcinoma by cDNA Microarray

IGFⅠR单克隆抗体可有效地抑制甲状腺乳头状癌细胞的增殖，而对正常滤泡上皮细胞伤害较小。

IGF - ⅰ R monoclonal antibody may effectively inhibit primary carcinoma cells while it is less detrimental to normal follicular cells .

甲状腺乳头状癌颈部转移性淋巴结组和非转移性淋巴结组之间上述超声指标的差异均具有统计学意义（P0.05）。

Thyroid papillary carcinoma metastatic lymph node group and neck non-metastatic lymph node group differences between the ultrasonic index was statistically significant ( P0.05 ) .

EGCG诱导甲状腺乳头状癌细胞凋亡及对Survivin蛋白表达的影响

EGCG Inducing Apoptosis of Thyroid Papillary Carcinoma and Its Influence on the Expressions of Survivin Protein

目的：探讨甲状腺乳头状癌中缺氧诱导因子-1α（HIF-1α）、血管内皮生长因子（VEGF）和VEGF-C表达的临床意义。

Objective : To evaluate clinical significance of HIF-1 α、 VEGF and VEGF-C expression in papillary thyroid carcinoma .

甲状腺乳头状癌病理分级、有无淋巴结转移与p53蛋白阳性表达率有关。

The pathological grading and presence or absence of lymphatic metastasis of thyroid papillary adenocarcinoma were related to the positive expression of p53 protein .

结论：甲状腺乳头状癌ER阳性率显著高于滤泡状癌及正常组织甲状腺乳头状癌的发生与雌激素关系密切，检测其ER有助于指导治疗。

Conclusion : Thyroid papillary carcinoma was associated with estrogen , and detection of ER in thyroid papillary carcinoma was helpful for the treatment .

VEGF、VEGF-C和VEGF-D在甲状腺乳头状癌组织中的表达及意义

Expression and Significance of VEGF , VEGF-C , and VEGF-D in Papillary Thyroid Carcinoma

TPO在甲状腺乳头状癌与乳头状增生鉴别诊断中的作用

Role of thyroperoxidase in differential diagnosis between malignant and benign thyroid papillary hyperplasia

微小病毒B19感染与甲状腺乳头状癌的关系

The Association between Parvovirus B19 Infection and Papillary Thyroid Carcinoma

甲状腺乳头状癌患者ret基因重排突变

Ret rearrangement mutation in patients with papillary thyroid carcinoma

细胞角蛋白和Ret蛋白在甲状腺乳头状癌中的表达

Expression of cytokeratins and ret in thyroid papillary carcinoma

结论癌胚胎纤维连接蛋白mRNA在乳头状癌中特异性表达，提示癌胚胎纤维连接蛋白mRNA有可能成为甲状腺乳头状癌的一种分子生物指标，具有一定的潜在性临床应用价值。

Conclusions It is suggested that oncofetal fibronectin mRNA , which specially expressed in the thyroid papillary carcinomas , may become a biological marker with potentially clinical value .

上皮钙粘附蛋白在甲状腺乳头状癌中的表达与血清TSH浓度相关性的临床研究

Clinical research of relativity between the expression of E-cadherin in papillary thyroid carcinoma and serum TSH concentration

甲状腺乳头状癌中p21ras蛋白、转化生长因子β1和ki-67的表达

Expression of p21 ras Protein , Transforming Growth Factor β _1 and ki-67 in Papillary Thyroid Carcinoma

结果甲状腺乳头状癌组织MMP-2阳性表达率为74.8%（86115）。

Results The expression rate of MMP-2 in papillary carcinomas of thyroid was 74.8 % ( 86 / 115 ) .

颈中央区域淋巴结清扫58例颈淋巴结阴性（cN0）甲状腺乳头状癌手术治疗应用

Application of Neck Central Lymph Node Dissection to Surgical Treatment for 58 Cases with Papillary Thyroid Carcinoma Stage cN_0