自身免疫性甲状腺炎

目的系统评价补硒治疗自身免疫性甲状腺炎（AITD）的效果和安全性。

Objective To systematically evaluate the efficacy and safety of selenium in treatment of autoimmune thyroiditis ( AITD ) .

方法：将IL-10质粒DNA注射入由猪甲状腺球蛋白（pTg）诱发的自身免疫性甲状腺炎小鼠甲状腺内，pTg免疫后28天，进行甲状腺IL-10mRNA表达和组织学等检查。

METHODS : Mice were immunized to induce autoimmune thyroiditis with porcine thyroglobulin ( pTg ), and thyroids of mice were injected with IL-10 DNA . On d 28 after immunization with pTg , mRNA expression of IL-10 in thyroid glands was detected and thyroid specimens were histopathological studied .

环孢菌素A和1,25（OH）2D3防治实验性自身免疫性甲状腺炎的研究

Cyclosporin A and 1,25-Dihydroxyvitamin D_3 in the Prevention and Treatment of Experimental Autoimmune Thyroiditis

目的：研究CD4+CD25+Treg细胞对诱导小鼠实验性自身免疫性甲状腺炎（EAT）的影响。

Objective : To investigate the immunosuppression of mouse CD4 ~ + CD25 ~ + regulatory T ( Treg ) cell .

目的：研究温肾方对大鼠实验性自身免疫性甲状腺炎（EAT）白细胞介素-1（IL-1）的影响。

Objective : To Investigate the effect of Wenshenfang in the treatment of experimental autoimmune thyroiditis ( EAT ) by observing IL-1 in thyroid tissues .

方法：Wistar大鼠分为对照组、自身免疫性甲状腺炎（EAT）组和硒治疗EAT组。

Methods : Wistar rats were divided into three groups : normal control , experimental autoimmune thyroiditis ( EAT ) group and selenium cura - tio-EAT group .

方法运用猪甲状腺球蛋白和高碘水（0.05%）在健康Wistar大鼠上复制自身免疫性甲状腺炎模型，同时设立正常大鼠为对照组。

Methods : Pig thyroglobulin and iodine-rich water ( 0.05 % ) were adopted to induce EAT in Wistar rats . Unimmunized rats were used as control .

目的研究T细胞疫苗（TCV）在小鼠实验性自身免疫性甲状腺炎（EAT）发生中的阻断作用及可能机制。

Objective To investigate the prevention of mouse experimental autoimmune thyroiditis ( EAT ) induced by T cell vaccination ( TCV ) .

结论：甲状腺直接注射编码IL-10质粒DNA能显著抑制自身免疫性甲状腺炎淋巴细胞对甲状腺的浸润，缓解病情的发展。

CONCLUSION : The direct injection of DNA expression vectors enoding IL-10 into thyroid significantly inhibited development of lymphocytic infiltration of thyroid of autoimmune thyroiditis mice , and alleviated the progression of this disease .

动物实验也表明，碘摄入量增加能加重具有遗传倾向的AITD动物模型的自身免疫性甲状腺炎。

Animal studies showed that increased iodine intake can promote the development of AITD in genetically predisposed strains .

自身免疫性甲状腺炎患者血清TSH、甲状腺自身抗体与甲状腺细胞病理学改变的相关性加贝酯对胆源性重症胰腺炎免疫功能的影响

Correlation of serum TSH and thyroid autoantibodies with cytopathologic changes of thyroid in autoimmune thyroiditis Effects of Gabexate on Immunity in Patients with Biliary Sever Acute Pancreatitis

慢性碘过量对具有自身免疫性甲状腺炎遗传倾向的NOD.H-2～（h4）小鼠甲状腺功能和形态影响的实验研究

The Effects of Chronic Iodine Excess on Thyroid Function and Structure in Autoimmune-prone NOD . H-2 ~( h4 ) Mice

目的观察人类甲状腺球蛋白（hTG），人类甲状腺过氧化物酶（hTPO）以及豚鼠促甲状腺激素受体（gTSHR）免疫诱导Wistar大鼠产生实验性自身免疫性甲状腺炎（EAT）的过程。

Objective The development of experimental autoimmune thyroiditis ( EAT ) was investigated by immunization of Wistar rats with human thyroglobulin ( hTG ) , human thyroid peroxidase ( hTPO ) and guinea pig thyroid stimulating hormone receptor ( gTSHR ) .

慢性自身免疫性甲状腺炎患儿糖代谢临床研究

Clinical study on carbohydrate metabolism of the children with Hashimoto thyroiditis

硒对自身免疫性甲状腺炎大鼠甲状腺细胞凋亡的影响及其机制研究

Effect of Sodium Selenite on Apoptosis of Experimental Autoimmune Thyroiditis

碘对实验性自身免疫性甲状腺炎Th1/Th2型细胞因子表达的影响

Effects of Iodine on Expression of Th1 / Th2 Cytokines in EAT

温肾方对实验性自身免疫性甲状腺炎的影响

Effect of Wen Shen Fang on Experimental autoimmune thyroiditis

亚硒酸钠对大鼠自身免疫性甲状腺炎影响的研究

Influence of Sodium Selenite on Rats with Autoimmune Thyroiditis

碘和甲状腺球蛋白诱导大鼠自身免疫性甲状腺炎的研究

Studies on Induction of Experimental Autoimmune Thyroiditis with Excessive Iodine and Thyroglobulin in Rats

小鼠实验性自身免疫性甲状腺炎的初步研究

Studies on the Experimental Autoimmune Thyroiditis of Mice

与自身免疫性甲状腺炎相关的激素敏感性脑病

Hormone Steroid-responsive encephalopathy associated with autoimmune thyroiditis

T细胞疫苗抑制自身免疫性甲状腺炎的发生

T cell vaccination prevents experimental autoimmune thyroiditis

白癜风儿童和青少年中慢性自身免疫性甲状腺炎（桥本甲状腺炎）的患病率增高

Increased prevalence of chronic autoimmune ( Hashimoto 's ) thyroiditis in children and adolescents with vitiligo

碘硒干预对自身免疫性甲状腺炎抗氧化及凋亡的影响

The Effect of Administration of Iodine and Selenium on the Antioxidation and Apoptosis with Autoimmune Thyroiditis

目的麻雷汤是导师许芝银教授数十年治疗自身免疫性甲状腺炎临床有效方。

Purpose : Ma Lei Tang is Professor Xu Zhiyin decades clinically effective treatment of autoimmune thyroiditis .

目的：观察雷公藤对实验性自身免疫性甲状腺炎的作用效果及机理。

Object To observe the effects and mechanism of Leigongteng to experimental autoimmune thyroiditis ( EAT ) .

瘦素在自身免疫性甲状腺炎中的免疫调节机制过量碘致甲状腺自体免疫性疾病作用

Effect of leptin on the induction of experimental autoimmune thyroiditis Immunoregulation mechanism of AITD caused by excessive iodine

过量碘致甲状腺自体免疫性疾病作用硒对自身免疫性甲状腺炎大鼠甲状腺细胞凋亡的影响及其机制研究

Immunoregulation mechanism of AITD caused by excessive iodine Effect of Sodium Selenite on Apoptosis of Experimental Autoimmune Thyroiditis

甲状腺滤泡上皮细胞长期培养模型的建立，为进一步研究细胞免疫在自身免疫性甲状腺炎中的作用打下了基础。

This human epithelial cells long term culture model might be useful for the study of autoimmune thyroiditis pathogenesis .

CD4~+CD25~+调节性T细胞抑制小鼠自身免疫性甲状腺炎的发生

Study of CD4 ~ + CD25 ~ + regulatory T cells in preventing adoptive transfer of experimental autoimmune thyroiditis