点突变

扩张型心肌病患儿线粒体DNA点突变研究

The study of mitochondrial DNA point mutation in children with dilated cardiomyopathy

心肌病中新的线粒体DNA点突变

A New Point Mutation of Mitochondrial DNA in Cardiomyopathy

双链DNA膜效应在序列点突变电化学检测中的应用

DNA duplex membrane effect for the electrochemical detection of single-base DNA mutations

早发性帕金森病患者线粒体DNA部分点突变的研究

Mitochondrial DNA partly point mutations in praecox Parkinson 's disease

线粒体DNA部分点突变与遗传性共济失调的关系研究

Mitochondrial DNA point mutations studies in hereditary ataxia

前言：目的：探索线粒体DNA点突变与遗传性共济失调的关系。

Objective : To study the possible relationship between mitochondrial DNA point mutations and hereditary ataxia .

目的介绍氧化胁迫对线粒体的影响，人体线粒体DNA的结构，线粒体DNA点突变及缺失与衰老的关系。

Objective To review the progress in the studies of oxidative stress and mitochondrial DNA mutations with aging .

非综合征家族性耳聋线粒体DNA1555~（A→G）点突变分析

Mitochondrial DNA 1555 ~ ( A → G ), point mutation analysis on familial nonsyndromic deafness

恶性间皮瘤p53基因点突变和蛋白表达

Gene p53 point mutation and protein expression in human malignant mesothelioma

凝血因子V基因点突变1691A在不同种族人群中的分布

Distribution of coagulation factor V gene mutation 1691 a in populations of different races

结论提示线粒体DNA点突变是导致该家系致聋的主要因素之一。

Conclusion Mitochondrial DNA mutation may be one of major factors resulted in aminoglycoside antibiotic-induced deafness in this pedigree .

对rrrA基因83位C－T的点突变，设计错配引物，以错配PCR的方法检测福氏志贺菌的耐药突变。

To fixed point mutant , mismatch primer was designed and Shield flexneri were detected by mismatch PCR .

用点突变PCR方法去除人IL－2cDNA表达克隆终止密码及其鉴定

Deleting stop Codon of Human IL-2 cDNA Expression Clone through Side Mutation PCR and Identification

喉癌p53基因点突变研究

Pilot Study on Mutations of p53 Gene in Laryngeal Carcinoma

肝细胞癌p53基因特异点突变的分子流行病学意义

Molecular epidemiologic significance of aflatoxin B1 characteristic mutational point in hepatocellular carcinoma

p53基因第7外显子点突变与乳腺癌的关系

Study on point mutations in p53 exon 7 in human breast carcinoma

肺癌原癌基因c－Ha－ras点突变的研究

Proto-oncogene Point Mutation of c-Ha-ras in Bronchogenic Carcinoma

p53基因点突变与胃粘膜细胞癌变的关系

High frequency mutation of p53 gene in human gastric cancer and precancerous lesions

恶性卵巢上皮肿瘤的P53基因点突变及其意义

Mutation of P53 Gene in Ovarian Malignant Epithelial Tumors and Its Clinical Significance

8-MOP/UVA诱导体外培养真皮成纤维细胞线粒体DNA复制控制区点突变研究

Study on point mutations in mitochondrial DNA control region for replication DLP_6 of cultured dermal fibroblast with 8-MOP / UVA treatment

大肠癌的p53基因点突变

P53 gene point mutation in human colorectal carcinoma

目的探索点突变p53肽诱导细胞免疫应答的可能性，为其作为肽疫苗用于肿瘤免疫治疗提供实验依据。

Objective To explore the possibility of inducing cell-mediated immune response with p53 peptides .

胰腺癌组织中K－ras基因点突变的研究

Point mutation of K-ras gene in pancreatic carcinoma

对疑有点突变的病例，进行DNA序列测定，以明确其具体的突变性质。

The PCR products of suspected cases with the point mutation were further DNA sequenced so as to determine its mutation characters .

然后用SSCP和DNA测序方法分析点突变。

DNA point mutations were analyzed by using SSCP and DNA sequencing methods .

近年来发展了一种用于定量检测基因点突变的电化学发光PCR方法。

Recently , we have developed an electrochemiluminescence-polymerase chain reaction ( ECL-PCR ) method for point mutation detection .

膀胱癌P53基因点突变的观察

P53 gene point mutation in bladder cancer

点突变p53肽诱导肽特异性CTL的研究

Induction of peptide specific cytotoxic lymphocytes with a mutant p53 peptide

肾癌组织中ras基因产物p21表达和K－ras基因点突变分析

Expression of p21 Ras and K-ras gene mutation in human renal cancer

目的研究肝细胞癌（HCC）中p53基因249密码子（p53E7cd249）点突变情况。

Objective To study the hotspot mutation of p53 codon 249 in hepatocellular carcinoma .