流脑疫苗

靖江市部分幼儿A群流脑疫苗基础免疫效果及其影响因素分析

Immune Effects and Its Impact Factors of Epidemic Cerebrospinal Meningitis Group A Polysaccharide Vaccine for Children in Jingjiang

A+C流脑疫苗接种后抗体阳性率较接种前A群上升了104%，C群上升了160%；

Antibody positive rate for A type and C type Neisseria meningitidis increased 104 % and 160 % respectively after vaccinating A + C epidemic meningitis vaccine .

六类人不适宜接种流脑疫苗1.中枢神经系统感染的病人不能接种。

The patient that central nervous system affects cannot vaccinal . 2 .

健康人群的C群抗体水平随着年龄的增加降低明显，因此应做好扩大免疫规划工作，提高大年龄青少年和成年人的A+C流脑疫苗的接种率。

The antibody levels of group C of healthy population significantly decreased with the decreasing of age . We should do more about the immunity programming to raise the vaccine inoculation rate of ( A + C ) meningitis of young people and adults .

目的对在广西壮族自治区河池市进行的成人及儿童伤寒Vi疫苗及A群流脑疫苗大规模预防接种活动的组织实施、安全注射、冷链管理、宣传发动以及接种率的结果进行描述和分析。

OBJECTIVE To describe and analyze the implementation , safety injection , cold chain management , promotion and coverage of a mass vaccination campaign for children and adults using typhoid Vi and group A meningococcal vaccines in Hechi , Guangxi .

结果应接种对象118071人，实际接种92476人，接种率为7832%，其中伤寒Vi疫苗7687%；流脑疫苗7969%。

Results 92,476 people of the total target population of 118 、 071 were vaccinated ; Vaccination coverage reached 78 32 % , typhoid Vi vaccine coverage reached 76 87 % and meningococcal A vaccine coverage reached 79 69 % .

方法采用组群随机试验方法确定试验组和对照组所需样本量，并组织实施大规模疫苗接种，在试验组接种伤寒Vi疫苗、对照组接种流脑疫苗。

Methods Simple size calculation of cluster-randomized trial was used to determine the sample size of the two groups and a vaccination campaign was conducted . The study group was given typhoid Vi vaccine and the control group was given meningococcal A vaccine .

有A群流脑疫苗免疫史占82.14%，有5例流脑A+C二价疫苗免疫失败。

82.14 % cases were vaccinated with serogroup A vaccine .

流脑疫苗的免疫史对健康人群的带菌率无直接影响。

The immunization history of healthy population had no direct impact on the carrier rate .

疫苗总浪费率为11.10%，其中A群流脑疫苗较高。

The overall vaccine wasted was 11.10 % with a higher wastage for meningococcal A vaccine .

有流脑疫苗免疫史的健康人群带菌率显著低于无免疫史人群。

The carrier rate in healthy people with the history of meningitis vaccine was significantly lower than that of non-immune population .

所有这种强并非人人都能接受。六类人不适宜接种流脑疫苗1.中枢神经系统感染的病人不能接种。

All this toughness does not sit well on everyone . The patient that central nervous system affects cannot vaccinal . 2 .

[结果]五苗全程合格接种率97.36%，乙脑疫苗接种率为90.41%，流脑疫苗接种率为94.03%。

[ Results ] The vaccination qualified rate of the five kinds of vaccines were up to 97.36 % ; the vaccination rate of JEV and Meningitis were 90.41 % and 94.03 % ;

在民工中开展流脑疫苗接种，将A+C群流脑疫苗纳入常规免疫，预防性服药和有效的应急接种等是当前控制流脑发病的有效措施。

At present , effective measures for ECM control are carrying out ECM vaccination among peasant workers , adopting group A + C vaccine of epidemic cerebrospinal meningitis as routine immunity , and taking medicine for prevention and inoculating of effective emergency , et al .

在本组的41例病例中，发病平均年龄为（29.2±7.6）岁，其中20岁以上成人30例（73.17%），外来民工27例（65.85%），所有病例均未接种过流脑疫苗。

Among the 41 patients , the mean age was ( 29.2 ± 7.6 ) years and ages of 30 ( 73.17 % ) cases was over 20 years old . 27 ( 65.85 % ) patients were rural workers . No vaccination was implemented in all of patients before .

合肥市18～25岁健康人群流脑免疫水平及A+C流脑疫苗免疫效果检测分析

Epidemic Meningitis Immunity Level of Natural Population at Age of 18-25 and Analysis of Immunity Effect of A + C Epidemic Meningitis Vaccine

目的了解合肥市18～25岁人群流脑免疫水平，评价A+C流脑疫苗接种效果，为合理制定流脑A+C疫苗接种方案提供依据。

Objective To understand epidemic meningitis immunity level of natural population at age of 18-25 and evaluate immunity effect of A + C epidemic meningitis vaccine so as to provide reasonable basis for making A + C epidemic meningitis vaccination scheme .

南京市健康儿童流脑A群和C群抗体水平监测及A+C群流脑疫苗免疫效果分析

Monitoring on the antibody levels of meningitis serogroup A and C and immunization effect of a and C meningococcal polysaccharide vaccine among health children in Nanjing