氧化呼吸链

泛醌（辅酶Q）在生物体氧化呼吸链中作为重要的质子和电子传递物质。

Ubiquinone ( Coenzyme Q ), known as a carrier of electrons and protons is a redox-active lipid essential in aerobic respiration .

AIF（apoptosis-inducingfactor）是一个典型的双功能基因，其蛋白质在正常细胞内是线粒体氧化呼吸链调控分子之一，而在病理状态下AIF是非Caspase依赖的细胞程序性死亡诱导物之一。

As a typical bifunctional gene , AIF ( apoptosis-inducing factor ) described as a regulatory molecule of MRC ( Mitochondrial Respiration Chain ) in the physiological state , while in pathological condition it function as a death inducer involving in caspase-independent PCD ( Programmed Cell Death ) .

方法利用Fe2+/抗坏血酸损伤体系在体外攻击线粒体模型，观察对线粒体脂质过氧化、呼吸链细胞色素含量及复合物活性的影响。

Methods Mitochondria were injured by Fe 2 + / VitC in vitro and the content of lipid peroxidation ( LPO ) and cytochrome , activity of complex ⅳ was observed .

目的：观察马齿苋水提液对衰老模型小鼠心肌线粒体磷脂的脂质过氧化和呼吸链酶活性的影响，分析其心肌保护作用途径。

OBJECTIVE : To observe the effects of the Portulaca water extract on the lipid peroxidation myocardial mitochondrial phospholipid and the activity of respiratory chain enzymes in aging model mice , and analyze the pathway of protective effect on myocardial mitochondria .

结论：马齿苋水提液可能通过抑制心肌线粒体磷脂的脂质过氧化和改善呼吸链酶的活性而实现对线粒体的保护作用。

CONCLUSION : The Portulaca water extract has the protective effect on myocardial mitochondria by inhibiting the lipid peroxidation in myocardial mitochondria and enhancing the activities of respiratory chain enzymes .