柔红霉素

柔红霉素与DNA作用的序列特异性研究

Studies on the Interaction of Daunomycin and the Specific Sequence of DNA

紫杉醇对柔红霉素与DNA作用影响的研究

Influence of Paclitaxel on the Interaction between Daunorubicin and DNA

柔红霉素修饰的纳米金电极的制备及其对DNA检测

Preparation of Daunomycin Modified Nano Gold Electrode and Its Application to Detection of DNA

用钴离子注入修饰电极研究了柔红霉素与DNA的相互作用。

With Co / GCE as the working electrode , an interaction between daunorubicin and DNA was studied .

盐酸柔红霉素能嵌入DNA双螺旋中与DNA结合，使其模板发生改变，抑制DNA和RNA聚合酶，阻止DNA和RNA的合成。

It has characters of binding of daunomycin to DNA and the inhibition of RNA and DNA synthesis .

汉防己甲素联合柔红霉素对K562/A02细胞株P21蛋白和P糖蛋白表达的影响

Effect of Tetrandrine Combined with Daunorubicin on Expressions of P21 and P-gp in K562 / A02 Cells

柔红霉素联合bax基因转染对兔实验性增生性玻璃体视网膜病变的影响

Combined effects of daunorubicin and bax gene transfection on rabbit proliferative vitreoretinopathy

乌索酸诱导K562细胞与耐柔红霉素的K562细胞凋亡及其机制的初步研究

Study on Ursolic Acid-Induced Apoptosis in K562 and K562 / DNR Cells

Caspase-3在柔红霉素诱导的人视网膜色素上皮细胞凋亡中作用

Caspase-3 activity during daunorubicin induced human retinal pigment epithelium cell apoptosis

转染反义Bcl-2对柔红霉素诱导人视网膜色素上皮细胞凋亡的影响

Effect of transfection with anti-sense Bcl-2 on daunomycin induced apoptosis of human retinal pigment epithelial cells

建立脂质体中柔红霉素含量测定的可见分光光度法和HPLC方法；

Visible spectrophotometry and the HPLC method were established for determination of the daunorubicin in the long circulating liposomes .

柔红霉素对K562细胞凋亡的影响

Influence of daunorubicin on apoptosis factor of K562 cells

小剂量柔红霉素对HL-60细胞增殖分化的影响

Effects of Low-dose Daunorubicin on Proliferation and Differentiation of HL-60 cells

去甲氧基柔红霉素在一定范围内对HL-60细胞的杀伤作用呈剂量、时间依赖性。

The effect of IDA was dosage and time - dependency .

柔红霉素体外对HL-60细胞的凋亡作用

The apoptosis effect of daunorubicin on HL-60 cells in vitro

重组变构人TRAIL联合柔红霉素对白血病细胞诱导凋亡作用及其机制的研究

Combined Effect of Recombinant Mutant Human TRAIL and Daunorubicin in Inducing Apoptosis of Leukemia Cell and Its Mechanism

银盘电极盐酸柔红霉素电化学行为及其与BSA的相互作用

The Electrochemical Behavior of Daunorubicin Hydrochloride on Galactic Disk Electrode and its Reaction with BSA

NF-κB与柔红霉素对HL-60细胞凋亡作用关系的探讨

In vitro study on the relationship between nf - κ b and the apoptosis effect of daunorubicin ( dnr ) on HL-60 cells

蒽环类抗生素柔红霉素（DNR）、表柔比星（EPI）、米托葸醌（MXT）与刚果红（CR）相互作用的反应体系；

Anthracycline antibiotics such as daunomycin , epirubicin , mitoxantrone and congo red systems ;

柔红霉素作用后G2期细胞由9.9%增加至30.4%；

The percentage of cells in G2 increased from 9.9 % to 30.4 % ;

铁剥夺对柔红霉素诱导K562细胞多药耐药基因1表达及NFκB活化的影响

Effects of iron-deprivation on the activation of NF κ B and the expression of multidrug resistance gene 1 of K562 cells induced by daunorubicin

方法采用甲基四唑蓝法（MTT）测定柔红霉素（DNR）的细胞毒性；

Methods The cytotoxicity of daunorubicin ( DNR ) was assayed by MTT method .

柔红霉素在人敏感和抗三尖杉酯碱的HL－60细胞中分布和积聚变化

Changes of the distribution and accumulation of daunorubicin in the sensitive and harringtonine-resistant HL-60 cells

另外，以柔红霉素为指示剂，检测DNA电化学探针对目标DNA的识别能力，柔红霉素响应信号明显。

In addition , we use daunomycin as indicator to test the recognition of DNA electrochemical probe on the target DNA . As a result , response signal is significant and satisfactory .

目的探讨天冬酰胺特异酶切的半胱氨酸蛋白酶（caspase）成员caspase-3在柔红霉素诱导的人视网膜色素上皮（RPE）细胞凋亡中的变化。

AIM To study the function of caspase-3 activity during daunorubicin induced human retinal pigment epithelium cell apoptosis .

柔红霉素C-14羟化酶基因在E.coli中的克隆、融合表达及酶的纯化

Cloning and Expression of doxA Gene Encoding Daunorubicin C-14 Hydroxylase in E.coli and Its Purification

结论Caspase-3参与了柔红霉素诱导的人视网膜色素上皮细胞的凋亡，柔红霉素可使其活性增加。

CONCLUSION Caspase-3 is involved in daunorubicin induced human retinal pigment epithelium cell apoptosis , and daunorubicin could raise the activity of caspase-3 .

去甲氧柔红霉素联合Ara-C治疗难治性白血病

The idarubicin in combination with ara C treatment of refractory leukemia

结果K562/ADM细胞对阿霉素呈高度耐药性，并与柔红霉素和鬼臼乙叉甙交叉耐药，但与CsA无交叉耐药。

Results K562 / ADM cells were highly resistant to adriamycin , and cross-resistant to daunorubicin and etoposide , but uncross-resistant to CsA .

诱导治疗主要采用全反式维A酸诱导分化，继以柔红霉素-阿糖胞苷（DA）、三尖杉酯碱-阿糖胞苷（HA）、柏林-法兰克福-慕尼黑（BFM）方案巩固治疗。

The patients were treated with protocol including induction of differentiation with ATRA followed by consolidation therapy with DA , HA or BFM protocol .