杂合性

胃癌中p53基因杂合性丢失的研究

A Study on Loss of Heterozygosity of p53 Gene in Human Gastric Cancer

目的：探讨微卫星DNA杂合性缺失与急性淋巴细胞白血病（ALL）的相关性。

Aim : To explore the relationship between loss of heterozygosity ( LOH ) of microsatellite DNA and a-cute lymphoblastic leukemia ( ALL ) .

B细胞淋巴瘤微卫星不稳定性及杂合性缺失的研究

The study of loss of heterozygosity and microsatellite instability in B-cell lymphoma

循环DNA杂合性缺失作为肿瘤标志物在肺癌诊断上的应用

Analysis of Circulating Tumour DNA in Plasma to Diagnosis Lung Cancer

四川省主要杂交稻组合DNA杂合性的比较

DNA heterozygosity between major combinations of hybrid rice in Sichuan

新的双重杂合性FⅤ基因突变导致的重型遗传性FⅤ缺陷症

Severe hereditary coagulation factor ⅴ deficiency caused by two novel heterozygous mutations

过氧化物酶杂合性与玉米F1产量性状相关性分析

Relationship of Peroxidase Diversity with F_1 Yield in Maize

肝细胞癌患者p53基因杂合性丢失的研究

Study on LOH ( Loss of heterozygosis ) of p53 gene in human hepatocellular carcinomas

一个水稻三倍体×二倍体杂交F2群体的微卫星杂合性丧失

Loss of Heterozygosity at SSR Loci in F_2 Population Derived from the Cross of Triploid × Diploid in Rice

2例有CKIT基因11号外显子杂合性突变。

Of the five cases examined for heterozygous deletion mutation of 11 exon of the c-kit gene two were found positive .

PCR一SSCP变性聚丙烯酞胺凝胶电泳检测PTEN杂合性缺失。

PTEN LOH : PCR - SSCP denaturing PAGE gel electrophoresis and sliver staining .

脑胶质瘤中EGFR基因扩增和10号染色体杂合性丢失的研究

Amplification of EGFR Gene and Loss of Heterozygosity on Chromosome 10 in Human Gliomas

肝细胞肝癌细胞p53基因第2～3,4,11外显子纯合性缺失、杂合性缺失的分析

Homozygous deletion and loss of heterozygosity of p53 gene exon 2 ~ 3 , 4 and 11 in human hepatocellular carcinoma

结果发现：p53基因杂合性缺失率为34.0%（16／24）；

P53 gene was found to be partially deleted in 34.0 % ( 16 / 47 ) of breast cancer tissues .

小鼠淋巴瘤细胞Tk基因杂合性分析

Heterozygosity analysis of Tk Gene in Mouse Lymphoma Cells

乙基亚硝基脲诱导小鼠淋巴瘤细胞tk基因杂合性缺失

Loss of heterozygosity of TK gene in mouse lymphoma cells induced by ethylnitrosourea

抑癌基因DCC在肺癌中的表达及杂合性丢失

Expression and losa of heterozygosity of DCC gene inhuman lung cancer

方法：采用PCR及微卫星多态性技术，对65例肝癌1号染色体上28个微卫星标志位点杂合性缺失进行检测。

Methods : LoH of chromosome 1 were detected by PCR based microsatellite polymorphism analysis technique using 28 pairs of microsatellite markers primers in 65 HCC .

结果表明：杂交后代基因组的杂合性诱发了F1与异源四倍体广泛的序列消除；

The results indicated that extensive DNA sequence elimination was induced by the genomic merge in the allopolyploids .

Rb1基因在双眼视网膜母细胞瘤病人体细胞中杂合性突变的检测

Detection of Heterozygous Mutations of Rb1 Gene in Bilateral Retinoblastoma Patients

软组织平滑肌肉瘤染色体3p位点特异性的杂合性缺失

Specific loss of heterozygosity of chromosome 3p loci in soft tissue leiomyosarcoma

目的：探索表皮生长因子受体（EGFR）基因扩增及10号染色体杂合性丢失（LOH10）与胶质瘤发生、发展的关系。

Objective : To identify the EGFR gene and the loss of heterozygosity on chromosome 10 in human gliomas .

用微卫星位点进行杂合性缺失（LOH）分析。

LOH analysis was undertaken by using microsatellite markers .

乳腺癌与癌前病变的微卫星不稳定性与3p杂合性缺失

Microsatellite instability and allele-specific chromosome 3p deletion in breast cancer and precancerous lesions

在11例卵巢癌患者中，4例的正常组织为C－Ha－rasⅠ基因杂合性，其中1例呈现杂合性缺失。

Among 11 pairs of normal and cancer tissue samples , 4 ( 36.5 % ) normal tissues were heterozygous , 1 of these 4 heterozygosity was lost .

目的探讨6号染色体长臂的杂合性缺失（LOH）与膀胱肿瘤的关系。

ObjectiveTo investigate the loss of heterozygosity ( LOH ) on6q in bladder tumor .

脑胶质瘤中P53基因突变及其与染色体17p杂合性丢失的比较

P53 Mutation in Human Brain Gliomas : Comparison of Loss of Heterozygosity with Mutation Frequency

29例乳腺癌中有20例乳腺癌有p53基因杂合性缺失（LOH），缺失率为69%。

Twenty out of 29 ( 69 % ) tumors showed the loss of heterozygosity ( LOH ) in p53 gene .

利用ISSR标记对一些个体的遗传杂合性进行了研究，结果显示个体的平均杂合率为43.53%；

Genetic heterozygosity of some individuals was analyzed with ISSR , showing that the average was 43.53 % ;

利用9个随机引物分析了近年来四川省选育的籼型杂交水稻新组合的DNA杂合性。

DNA heterozygosity was analyzed on the new combinations of indica hybrid rice recently selected and bred using 9 primers to provide some inference for super high yield breeding in hybrid rice in Sichuan province .