抑癌基因
- 名Tumor suppressor gene;tumor suppression gene;cancer suppressor gene
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肿瘤中普遍存在DNA甲基化状态的改变,表现为抑癌基因的高甲基化与癌基因的去甲基化。
Change of DNA methylation commonly existed in tumor , which is shown to be highly methylated in cancer suppressor gene and hypomethylated in oncogene .
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PTEN蛋白是一种在骨肿瘤中也有表达的肿瘤抑癌基因蛋白,不仅可以用于肺癌、神经胶质细胞瘤等的研究,也可用于骨肿瘤的研究;
PTEN protein is a cancer suppressor gene protein which has expression in bone tumors . It might not only be used in the study of pulmonary carcinoma and neurogliocytoma , but also in the study of bone tumor ;
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抑癌基因P21CIP1/WAF1在食管癌中的表达及其预后意义
The Expression of P21 CIP1 / WAF1 in Carcinoma of the Esophagus and its Relation to Prognosis
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从石蜡包埋组织中提取DNA,是进一步研究抑癌基因的基础。
It is the foundation to further research anti-oncogene to extract DNA from paraffin embed constitution .
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方法回顾性分析11例肺癌肉瘤的临床表现,病理类型,CT特征及部分患者抑癌基因的表达,对其诊断及随访情况进行分析。
Methods 11 cases of lung carcinosarcoma proved by operation and pathology from 1994-2000 were analyzed .
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抑癌基因PTEN、P(53)与子宫内膜癌二元论
Tumor Suppressor Gene PTEN 、 P53 and the Dualistic Model of Endometrial Carcinoma
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高危性人乳头瘤病毒与抑癌基因P53在膀胱癌中的表达
High risk human papillomavirus and P53 protein expression in bladder cancer
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宫颈癌组织中乳头瘤病毒感染及抑癌基因p53突变的检测
Mutation of p53 gene and human papillomavirus infection in cervical carcinoma
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癌基因bcl-2及抑癌基因p53在宫颈癌组织中的表达及临床意义
Expression of gene bcl-2 and p53 in tissue of cervical carcinoma
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上皮性卵巢肿瘤中抑癌基因P53的表达及第8外显子突变的检测
Expression of P53 and detection of P53 exon-8 in epithelial ovarian tumor
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肝细胞癌抑癌基因p53突变
Mutation of p53 tumor suppressor gene in hepatocellular carcinoma
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人胃癌细胞系中p53抑癌基因变异的检测及其序列分析
P53 Gene Mutation in Chinese Gastric Carcinoma Cell Lines
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肺癌组织抑癌基因P53异常分析
Analysis of p53 gene alteration in human lung cancer
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涎腺腺样囊性癌DNA甲基转移酶与抑癌基因甲基化
Expression of DNA methyltransferases in salivary adenoid cystic carcinoma and its association with the CpG islands methylation of tumor suppressor genes
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抑癌基因bcl-2在玉米染色体中的荧光原位杂交定位
Physical Location of Tumor Suppressor Gene bcl 2 in Maize Chromosomes by FISH
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p53抑癌基因蛋白在外阴鳞癌和不典型增生组织中的表达
Expression of p53 Gene Protein in Squamous Cell Carcinoma and Precancerous Lesion of Vulva
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目的:研究青年人大肠癌抑癌基因p53蛋白的表达和细胞DNA含量。
Purpose To study the expression of p53 protein and DNA content in colorectal cancer of young adults .
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乙型肝炎病毒X蛋白转录抑制抑癌基因p53表达的研究
Transcriptional inhibitory effect of hepatitis B virus X protein on the expression of p53 tumor suppression gene
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P53是一个非常重要的抑癌基因,其基因表达的缺失或突变可导致肿瘤的发生。
Tumors can be induced with the loss or mutation of P53 tumor suppressor gene .
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p53基因是一种重要的抑癌基因,近年来发现,p53基因与细胞凋亡有密切关系。
P53 gene is an important anti-oncogene .
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卵巢癌抑癌基因P53的初步研究
The prospective study on P 53 gene in human ovarian cancer by nonisotopic PCR SSCP
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子宫肌瘤中抑癌基因p53和Rb的表达
Expression of p53 and Rb genes in human uterine leiomyoma
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大肠癌p53抑癌基因突变与组织类型、Dukes'分期的关系
P53 Gene Mutation in Colorectal Cancer and Its Relation to Histologic Grade and Dukes ' Stage
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胃Hp感染与癌前病变癌基因和抑癌基因表达的关系
Relationship between Hp infection and oncogene and tumor suppressor gene expressions in gastric cancer and precancerosis
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抑癌基因蛋白P33/ING1和survivin在宫颈癌中的表达
The Expressions of P33 / ING1 and Survivin Protein in Cervical Cancer
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小儿肾母细胞瘤的发生与p53抑癌基因突变关系的研究
A study of correlation between of occurrence of Wilms ' tumor with p53 tumor suppressor gene mutation
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抑癌基因p53对白血病K562细胞中心体异常的抑制作用及其机制
Inhibitory Effection and Mechanism of p53 Gene on Centrosome Abnormality in Leukemia Cell Line K562
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骨肉瘤中抑癌基因PTEN、Rb、p53蛋白的表达及相关性研究
Correlative study on expression of PTEN , Rb and p53 protein in osteosarcoma
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抑癌基因PTEN在人原发性肝细胞性肝癌中的表达、突变及其生物学意义
Involvement of PTEN Expression and Mutation in Human primary Hepatocellular Carcinoma
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中国成人动脉粥样硬化病变中p53抑癌基因的结构突变及与病变程度的关系
The mutations of p53 anti oncogene and the relation to the severity of atherosclerotic lesions in Chinese adults