肿瘤抗原

负载肿瘤抗原的DC疫苗对小鼠体内膀胱肿瘤的抑制作用

Inhibitory effect of dendritic cell vaccine plus tumor antigen on murine bladder tumor in vivo

结论：腺病毒介导的肿瘤抗原基因修饰的DC能有效诱导机体产生特异的抗肿瘤免疫反应。

Conclusion : The results demonstrated that specific antitumor immune responses cound be induced efficiently by vaccination with tumor antigen gene modified DC .

结果：肿瘤抗原致敏DC能有效刺激同基因型T淋巴细胞增殖反应；

Result : The tumor antigen-pulsed DCs could effectively stimulate the proliferation of T cells .

以该肿瘤抗原致敏外周血DC，诱导T细胞转变为CTL；

T cells and DCs were separated from peripheral blood .

肿瘤抗原冲击致敏的IL-2基因修饰的巨噬细胞治疗肾癌的实验研究

Therapy of renal cancer with tumor antigen-pulsed , IL-2 gene-modified macrophages

从卵巢癌cDNA表达文库筛选肿瘤抗原基因的研究

Analysis of human tumor antigens by Screening of cDNA expression library of ovarian carcinoma

MTT比色法检测成熟DCs激发的肿瘤抗原特异性CTL对肿瘤细胞的杀伤效应。

MTT assay was used to detect the cytolytic activity of CTL stimulated by DCs .

肿瘤抗原MAGE-2HLA-A2限制性新CTL表位的鉴定

Identification of novel HLA-A2-restricted CTL epitopes derived from tumor antigen MAGE-2

新型颗粒性肽-DNA复合疫苗有效激发肿瘤抗原特异性CTL反应

Novel particulate peptide-DNA dual vaccine effectively elicited tumor antigen specific CTL response

DC已经成功的被用来产生针对肿瘤抗原特异性细胞毒T细胞，诱导免疫耐受和T细胞极化。

They have been used successfully to generate cytolytic T cell activity against tumor antigens , induce immune tolerance and bring about changes in T-cell polarization .

肿瘤抗原MAGE-A亚家族共同B细胞表位预测及分析

Prediction of the common B cell epitopes derived from the tumor antigen MAGE-A sub-family

肿瘤抗原MAGE-12的B细胞表位4分支多重抗原肽的合成及鉴定

Synthesis and identification of B - cell epitope of tumor antigen MAGE - 12

热休克蛋白（Heatshockprotein，HSP）具有分子伴侣作用，参与肿瘤抗原的加工递呈，在诱导肿瘤免疫反应中发挥重要作用。

As molecular chaperone , heat shock protein ( HSP ) participates in processing and presentation of tumor antigen and plays an important role in eliciting antitumor immunity .

T细胞受体（TCR）Vβ基因1&20亚家族在识别和杀伤病毒及肿瘤抗原方面各自有着重要的作用。

T cell receptor ( TCR ) V β 1-20 genes have important roles in recognizing viral antigen and tumor antigen .

人树突状细胞体外提呈与EB病毒感染相关肿瘤抗原的研究

Generation of dendritic cells from human bone marrow and efficient presentation of tumor antigen associated with Epstein-barr virus

IL-18基因修饰增强肿瘤抗原多肽致敏的树突状细胞体内诱导的抗肿瘤免疫反应

Enhancing effect of IL-18 gene modification on the induction of antitumor immunity by antigen pulsed dendritic cells

结论SEB和肿瘤抗原联合修饰可以明显增强DC的活性（P<0.05）。

Conclusions The activity of DC modified by superantigen and tumor antigen can be enhanced conspicuously ( P < 0.05 ) .

肝癌相关肿瘤抗原AFP新的HLA-A2/A24限制性CTL表位的预测及分析

Prediction and analysis of a novel HLA-A2 / A24-restricted CTL epitope derived from AFP antigen associated with hepatocellular carcinoma

新城疫病毒HN基因对肿瘤抗原诱导的抗肿瘤免疫的增强作用

Newcastle disease virus gene HN augmented anti tumor immune response induced by tumor antigens

人食管癌Eca-109细胞Mr小于3000膜蛋白肿瘤抗原肽的筛选

Screening of tumor antigenic peptides in membrane antigen with M_r less than 3000 of human esophageal carcinoma Eca-109 cell line

弱酸洗脱提取的肿瘤抗原肽致敏的树突状细胞对CTL的体内外激活效应

In vivo and in vitro activation of CTL by murine dendritic cells pulsed with acid eluted tumor antigen peptides

目的：探讨负载肿瘤抗原的树突状细胞（DC）疫苗诱导的细胞毒性T淋巴细胞（CTL）的体外杀瘤作用及对荷瘤小鼠的治疗作用。

Objective : To explore the anti-tumor effects of cytotoxic of T-lymphocytes ( CTL ) induced by dendritic cells ( DC ) vaccine loaded with tumor antigen .

将TERT作为通用肿瘤抗原的肿瘤免疫治疗策略是很有前景的一种免疫治疗方法。

Thus , it may serve as a universal tumor antigen candidate for immunotherapy of cancer .

肿瘤抗原肽和鸡卵黄免疫球蛋白的IgY的分离和分析研究

Studies of Immunoglobulin of yolk ( IgY ) against Gardnerella Isolation and Analyse of Tumor Antigen and IgY

GM-CSF重组腺病毒扩增的骨髓树突状细胞体外经肿瘤抗原刺激后诱导抗肿瘤免疫应答

Tumor antigen pulsed dendritic cells generated from bone marrow by GM CSF adenoviral infection induce antigen specific tumor immunity

人食管癌Eca-109细胞膜肿瘤抗原筛选的研究

The Study on Screening Cytomembrane Tumor Antigens in Human Esophageal Carcinoma Eca-109 Cell Line

肿瘤抗原MAGE-3基因的克隆与原核表达

Cloning and prokaryotic expression of tumor antigen MAGE-3

肿瘤抗原MAGE-3基因的克隆及其重组表达载体的构建意义

Cloning of tumor antigen MAGE-3 gene and constructure of its recombinant eukaryotic expression vector

目的弱酸洗脱提取小鼠红白血病细胞膜表面肿瘤抗原肽，用于致敏树突状细胞（Dendriticcells，DC），观察其对细胞毒性T淋巴细胞（CTL）的体内外激活效应。

Objective To observe the activation effect on cytotoxic T lymphocytes ( CTL ) by murine dendritic cells ( DCs ) pulsed with mild acid eluted tumor antigen peptides presented on erythroleukemia cell surface .

目的探讨TIL识别的人黑色素瘤HLA-A2限制性的肿瘤抗原肽特性。

Objective : To explore the characteristics of human melanoma-specific antigen peptides by HLA-A2 restricted tumor-infiltrating lymphocytes .