慢性感染

日本血吸虫慢性感染致CD4~+T细胞凋亡的分子基础

Molecular basis for the apoptosis of CD_4 ~ + T cells induced by chronic infection of Schistosoma japonicum

丙型肝炎病毒慢性感染与IL-8、IP-10、Mig表达相关性研究

Relationship between HCV chronic infection and expression of IL-8 , IP-10 , Mig

对于慢性感染和肿瘤患者，DNA疫苗则可作为一种治疗措施。

DNA vaccine can physic chronic infected individuals and carcinoma .

HBV慢性感染相关的肝癌病人外周血树突状细胞亚群的特点及其意义

Characterization and significance of peripheral blood dendritic cell subsets in patients with HBV-associated hepatocellular carcinoma

结论：HBV慢性感染患者PBMC存在凋亡，其凋亡率较健康组明显增加。

CONCLUSION : There is apoptosis in PBMC of the HBV chronic infections .

由于HBV复制体系独特，在慢性感染者免疫压力等因素作用下，HBV经常发生突变。

HBV mutates frequently because of the unique HBV replication system , host immune pressure and other factors .

结论泛昔洛韦治疗HBV慢性感染安全有效。

Conclusion Famciclovir is an effective and safe nucleoside drug for the treatment of patients with chronic HBV infection .

HBV慢性感染的机制至今未能明确，长期以来缺乏合适的动物模型阻碍了HBV的研究进展。

The mechanism of chronicity of HBV infection is still unclear because of the lack of suitable animal models .

弓形虫（RH株）慢性感染小鼠空间学习记忆能力的初步研究

Effect of Chronic Toxoplasma Infection on the Spatial Learning and Memory Capability in Mice

已证明HPV感染与某些恶性肿瘤的发生有关系，慢性感染和反复发作患者的皮损局部易形成癌前病变或癌变。

Lesions in recurrent or chronic infection patients can develop to precancerous lesions or tumors .

全世界大约有20亿人感染过HBV，其3.5亿为慢性感染。

About 2 billion people have been infected the HBV . Among them 350 million people are chronic hapatitis B patients .

结论：HLA-DRB113011302基因是宿主抗HCV慢性感染的重要遗传因子。

Conclusion : HLA-DRB1 ~ 1301,1302 alleles is an important genetic factor for resistance to chronic HCV infection .

流行病学调查发现原发性肝癌与HBV、HCV慢性感染密切相关。

Epidemic disease investigation showed that Primary carcinoma of the liver and HBV and HCV chronic influence is related closely .

HBV可以引起肝脏的急、慢性感染，并可能发展为肝硬化、肝细胞性肝癌。

Viral infection may progress to acute or chronic hepatitis , and may eventually cause cirrhosis and hepatocellular carcinoma ( HCC ) .

方法随机观察98例HBV急慢性感染病例血液和肝、脾、肾、脑组织内HBVdna含量。

Method s Blood , liver , spleen , kidney and brain tissues were sampled at random from HBV infected patients for HBV DNA quantitative assay .

乙型肝炎病毒（HepatitisBvirus，HBV）感染是全球范围影响健康的重要问题，慢性感染人群存在肝硬化和肝细胞癌的高患病风险。

Persistent infection with hepatitis B virus ( HBV ) is a major worldwide health problem and chronically infected individuals are at high risk for cirrhosis and hepatocellular carcinoma .

HBV慢性感染与CXC趋化因子表达相关性研究

Study on the relationship between chronic infection of HBV and expression of CXC chemokines

乙型肝炎病毒（HepatitisBvirus，HBV）和丙型肝炎病毒（HepatitisCVirus，HCV）的慢性感染是人HCC发生的最重要的危险因素。

Chronic infections with hepatitis B virus ( HBV ) and hepatitis C virus ( HCV ) are the most important risk factors for the development of HCC in humans .

猴免疫缺陷病毒（SIV）慢性感染猴模型的建立

Establishment of Monkey Model with Chronic Infection of Simian Acquired Immunodeficiency Virus

HAART治疗HIV-1慢性感染儿童外周血特异性CTL的反应特点

Characters of HIV-1-specific CD8 T-cell responses in peripheral circulation of chronically HIV-1-infected children undergoing highly active antiretroviral therapy

研究背景及目的：乙型肝炎病毒（HBV）感染是影响全球人类健康的重要疾病，HBV慢性感染是形成人类肝细胞癌的主要致病因素。

Background and Objectives : The hepatitis B virus ( HBV ) infection is a worldwide human health problem and is a major risk factor for the formation of human hepatocellular carcinoma .

结果在80%的HIV-1慢性感染儿童外周血可检测到HIV-1特异性的tetramer+CTL细胞和HIV-1表位肽刺激的IFN-γ产生细胞。

Results It was found that HIV-1-specific CTL responses could be detected in vitro in more than 80 % of Chinese children with HIV-1 infection .

HBV和HCV是临床上最常见、危害最大的两种肝炎病毒，其长期持续的慢性感染与肝硬化、肝癌的发生发展密切相关。

HBV and HCV are the most common and harmful hepatitis viruses , the chronic infection of which are closely related to the development of cirrhosis and hepatocellular carcinoma ( HCC ) .

铜绿假单胞菌是（PseudomonasAeruginosa）一种机会致病菌，它可以在人群中引起严重的急性和慢性感染，是病人在医院期间发生感染的第三大致病菌。

Pseudomonas aeruginosa is an opportunistic pathogen . It can cause seriously acute and chronic infections in human beings , and is the third leading pathogen in nosocomial infections .

该文主要讨论HCV慢性感染的分子免疫学机制，包括由于基因突变导致的免疫逃避及HCV蛋白影响机体免疫功能的机制。

Here we discussed the molecular immune mechanisms of HCV persistence , including the immune evasion strategies evolved by this virus and the roles of HCV proteins in modulation of immune system .

有些膜性肾小球肾炎和慢性感染（如乙型肝炎）、肿瘤或SLE有关。但多数病例是特发性的。

Some cases of membranous GN can be linked to a chronic infectious disease such as hepatitis B , a carcinoma , or SLE , but many cases are idiopathic .

结论HCV慢性感染能诱导外周血单个核细胞表达IL8、I309、MIG和TARC。

Conclusion Chronic infection of HCV up-regulates the mRNA expression of IL-8 , I-309 , MIG and TARC in PBMC .

巨细胞病毒（CMV）是儿童先天性感染和生后获得性感染的重要病原，可引起多种急、慢性感染和神经系统迟发后遗症。

Cytomegalovirus ( CMV ) is an important pathogen of congenital and postnatal infections in children , which causes a series of acute and chronic infectious diseases and nervous system sequelaes .

背景：目前全世界有3320万艾滋病病毒（HIV）感染者，3.5-4亿乙肝病毒（HBV）携带者，1.5-1.7亿丙肝病毒（HCV）慢性感染者。

Background : At present , there are 33.2 million AIDS virus ( HIV ) infection , 350-400 million hepatitis B virus ( HBV ) carriers , 150-170 million hepatitis C virus ( HCV ) chronic infection in world .

方法：（1）研究对象：176例HBV慢性感染者（慢性乙型病毒性肝炎轻、中、重度，肝炎肝硬化，慢性重型肝炎和原发性肝癌）。

[ Methods ] ( 1 ) project subject : 176 patients ( Chronic hepatitis B with mild , moderate and sever ; liver cirrhosis , Chronic fulminant hepatitis and HCC ) with chronic hepatitis B virus infection were studied .