实质细胞

前期实验表明HPS在体外特异促进肝实质细胞增殖，对非肝来源的细胞和肝癌细胞没有相应的活性。

Early experiment suggested that HPS stimulated only hepatic parenchymal cell proliferation in vitro , no corresponding activity on non-liver cells or liver cancer cells .

结果表明：腺垂体实质细胞总数、GH细胞数随龄显著减少，GH细胞直径也随龄下降，以青年组到中年组减少最为明显（P＜0.05）。

The results show . There were significant age related declines in the adenohypophysial parenchymal cell number , GH cell number and diameter , which were most marked in the transition from youth to middle age ( P0.05 ) .

大鼠肝非实质细胞载脂蛋白CⅢ结合位点（受体）的研究

Apolipoprotein C ⅲ Binding Sites ( Receptor ) on Non-Parenchymal Cells from Rat Liver

松果体实质细胞肿瘤的CT和MRI诊断

CT and MRI diagnosis of pineal parenchymal tumors

背景：骨髓间充质干细胞（MesenchymalStemcells，MSCs）不仅能分化成间质细胞，而且能向实质细胞（如心肌细胞）转化。

BACKGROUND : Mesenchymal stem cells ( MSCs ) can differentiate not only into inter stitial cells but also into parenchyma cell ( e.g.myocardial cells ) .

为研究胡黄连提取物对四氯化碳（CCl4）或半乳糖胺（DGaIN）损伤原代培养大鼠肝实质细胞的保护作用。

The protective effect of the extracts of Rhizoma Picrorhizae on primary cultured hepatocytes injured by CCl 4 and D-GaIN was studied .

结论肝脏低温保存再灌注过程中，肝细胞内糖原能明显拮抗肝实质细胞凋亡的发生，其内在机理可能为肝细胞糖原通过抑制bax基因蛋白的表达从而达到拮抗肝实质细胞凋亡的发生。

Conclusion Intracellular abundant glycogen may significantly depress the hepatocellular apoptosis during hepatic cold preservation reperfusion by decreasing hepatocellular bax gene expression .

目的探讨输注同种异基因肝脏非实质细胞（NPC）对小鼠移植皮片存活的影响及其机制。

Objective To investigate the effect of allogene hepatic nonparenchymal cell ( NPC ) on the survival of grafted skin in mice and its underlying mechanism .

已有报道LPS诱导血管内皮细胞、平滑肌细胞等实质细胞凋亡是心血管疾病等的重要发病机制。

It is reported that , induced by LPS , the apoptosis of parenchymal cells like vascular endotheliocyte and smooth muscle cell , is important pathogenesis of angiocardiopathy .

与PLT组相比，IPC组于减体积肝移植术后24h肝实质细胞中Ref-1蛋白表达明显增高。

The expression of Ref-1 protein in IPC group was higher than that in PLT group at 24 h after reduced-size liver transplantation .

结论认为，用Percoll梯度液分离纯化肝细胞，可提高肝实质细胞纯度和活力，适合体外原代培养。

The conclusion is that the viability , purity and function of hepatocytes can be enhanced by Percoll grade centrifugation .

肝脏由实质细胞（肝细胞）和非实质细胞（包括Kupffer细胞、DC、内皮细胞和星状细胞）组成。

The liver consists of parenchymal cells ( hepatocytes ) and nonparenchymal cells ( NPC ), including Kupffer cells , sinusoidal endothelial cells , stellate cells , and hepatic dendritic cells .

结论在肝脏缺血再灌注时，Bcl2蛋白表达水平异常下调，其抑制细胞凋亡的效能减弱，促使肝实质细胞凋亡增加，加重肝脏缺血再灌注损伤。

Conclusion The down-regulation of the expression of Bcl-2 protein induces hepatocellular apoptosis during hepatic ischemia-reperfusion injury .

目的：研究经无唾液酸胎球蛋白（asialofetuin，AF）修饰后，脂质体达到小鼠肝实质细胞靶向的可能性。

To study the possibility of liposomes to target hepatocytes after being linked with asialofetuin ( AF ) .

结果KGFmRNA的表达除在NSCLC某些实质细胞内观察到外，主要见于NSCLC的纤维母细胞和血管平滑肌细胞胞质。

Results KGF mRNA expression was mainly observed in cytoplasm of fibroblast and blood vessel smooth muscle cell in mesenchyme of NSCLC , as well as in some parenchyma cells .

肝窦内皮细胞（Sinusoidalendothelialcells，SECs）作为肝脏非实质细胞之一，是肝窦壁的组成细胞，直接接受血流等力学刺激作用，其结构与功能可维持正常的肝脏微循环。

As one of hepatic non-parenchymal cells , sinusoidal endothelial cells ( SECs ) constitute the wall of hepatic sinusoid , receive the blood flow mechanical stimulation directly and maintain the normal hepatic microcirculation .

结论ICDH和CHE是反映肝实质细胞受损害及其合成代谢能力下降的敏感指标。

Conclusions ICDH and CHE were sensitive markers of reflecting the damage and liver synthetic metabolism of liver cell .

左心室肥厚的细胞病理学基础不仅表现在心肌实质细胞的肥大，还有心脏成纤维细胞（CFs）的过度增殖和细胞外基质大量沉积，导致心肌纤维化。

Besides cardiomyocytes hypertrophy , the pathological basis of left ventricular hypertrophy shows cardiac fibroblasts proliferation and excessive extracellular matrix protein accumulation , which leads to myocardial fibrosis .

结论：①db/db糖尿病可导致颌下腺组织萎缩及实质细胞形态学改变。②PCNA表达逐渐减弱，较对照组明显降低，说明糖尿病可能导致颌下腺腺体增殖活动的减弱。

PCNA was expressed in submandibular gland in both diabetic mice and control mice . Conclusion : db / db diabetes mellitus may induce submandibular gland atrophy and inhibit the proliferation of submandibular gland cells .

结论：肾衰保肾胶囊对残肾组织的功能和形态有保护作用，能通过Fas、CytC两条凋亡途径减少肾实质细胞凋亡，延缓慢性肾功能衰竭的进展。

It can reduce the apoptosis of renal parenchyma cells through Fas and CytC signal pathways , which can delay the progress of chronic renal failure .

组织损伤和缺血最终会产生缺血、缺氧、组织坏死、炎症因子等反应，促进实质细胞和炎症细胞合成并释放VEGF、bFGF等促血管新生因子。

Tissue injury and ischemia will eventually produce ischemia , hypoxia , tissue necrosis and inflammation factors , etc. This will promote parenchymal cells and inflammatory cells synthetize and release angiogenic factors , such VEGF , bFGF .

去唾液酸糖蛋白受体（AsialoglycoproteinReceptor，ASGPR）又称半乳糖受体，主要表达于哺乳动物肝窦状隙的肝实质细胞表面，参与多种生理功能。

Asialoglycoprotein receptor ( ASGPR ), also called galactose receptor , is predominantly expressed on the sinusoidal surface of mammalian hepatocytes and is involved in many physiological functions .

同时PMN激活引起氧自由基、花生四烯酸代谢产物和蛋白酶等释放，损伤血管内皮和实质细胞，是发生器官衰竭的重要原因。

Activated PMN release oxygen free radicals , prostaglandins and proteases , in turn , damage endothelial and parenchyma cells . This is an important factor in pathogenesis of multiple system organ failure .

番茄红素可降低肝脂，调节肝脏脂质代谢酶的活性，提高机体抗氧化能力减缓肝脏的脂质过氧化，调节VEGF的生成避免炎症反应扩大而保护肝脏实质细胞和肝脏血管。

Lycopene reduced hepatic lipid and peroxidation by regulating the activity of lipid metabolism enzymes and enhancing antioxidant capacity , and regulates the VEGF levels to prevent the inflammatory response from expanding , resulting in protecting the liver cells and liver blood vessels .

异种肝移植组NADPH-d组化染色呈强阳性，主要在肝实质细胞及浸润炎性细胞表达。

The expression of nitric oxide synthase was primarily present in both hepatocytes and portal inflammatory infiltrate cells for NADPH diaphorase histochemistry staining in orthotopic liver xenotransplantation .

以往对该病的研究多集中在观察实质细胞的变化以及免疫表型的研究，而对KFD的病理变化规律及增殖的淋巴细胞是否存在单克隆性等研究较少；

The research were concentrated on the changes of parenchymal cells of lymph node and immune phenotype in the last decade .

结论姜黄素可通过减少肝组织中NO生成、降低肝组织中ET-1表达来改善肝缺血再灌注早期损伤中微循环的紊乱，从而减少对肝缺血再灌注肝实质细胞的损伤。

Conclusion Curcumin can relieve the injury of hepatic cells by increasing the level of NO and decreasing the level of ET-1 in liver tissue to correct the disorder of liver microcirculation in the early injury of ischemia / reperfusion .

目的通过回输成纤维集落生成单位（CFU-F）促进骨髓实质细胞造血恢复。

Objective By transplantation of CFU-F to promote myeloid cell 's hemopoietic restoration , the patients are divided into two subgroups : simplicity chemotherapy and chemotherapy transplantation .

肝星状细胞（HSC）是肝脏的一种非实质细胞，HSC活化导致细胞外基质（ECM）的增加是肝纤维化形成并最终导致肝硬化、肝功能衰竭的主要原因。

Hepatic satellite cell is one kind of non-parenchymal liver cells . Activation HSC is the main cell that lead to the accumulation of extracellular matrix , which is the main reason of hepatic fibrosis , cirrhosis , liver failure .

同时分离肝脏移植物非实质细胞（NPC），应用流式细胞仪对移植物浸润细胞（GICs）的凋亡和CD4~+T细胞和CD8~+T细胞进行检测。

Meanwhile , the NPC of liver grafts was isolated so as to determine the apoptosis of GICs , CD_4 ~ + T cells and CD_8 ~ + T cells were assayed using flow cytometry .