急性肝功能衰竭

内毒素对SD大鼠急性肝功能衰竭模型血糖代谢影响的研究

Experimental Research of the Effect of Endotoxin on Glucose Metabolism in SD Rats Model With Acute Hepatic Failure

目的探讨ABO血型不合的肝移植治疗急性肝功能衰竭的疗效。

Objective To investigate the effect of ABO-incompatible liver transplantation on patients with acute hepatic failure .

急性肝功能衰竭大鼠eNOS及iNOS的表达

Expression of eNOS and iNOS in rats of acute liver failure

肝细胞移植（HCT）是治疗暴发性或急性肝功能衰竭及某些和肝脏有关的代谢性疾病的一种有效的方法。

Hepatocyte transplantation is an effective therapy on fulminant or acute hepatic failure and some liver-associated metabolic diseases .

目的调查分析急性肝功能衰竭（ALF）的病因、转归及影响因素。

Objective To analyze the causes and prognostic factors of patients with acute liver failure ( ALF ) .

结论每公斤体重4mL四氯化碳灌胃可用于SD大鼠急性肝功能衰竭模型的建立。

[ Conclusion ] Feeding carbon tetrachloride 4 mL per kilogram body weight in SD can establish an animal model with acute hepatic failure .

目的A型肝性脑病（hepaticencephalopathy，HE）是急性肝功能衰竭并发的大脑功能障碍，该病来势凶险，生存率仅为20%。

Objective Hepatic encephalopathy ( HE ) of type A is a kind of encephalopathies associated with acute liver function failure . It is dangerous and the survival rate of it is only 20 % .

结果12例行TAE后出血均得到完全控制，所有病例均无复发出血及急性肝功能衰竭。

Results Successful hemostasis was achieved in all patients , there were no recurrent hemorrhage and acute hepatic function failure after the treatment in all cases .

急性肝功能衰竭（ALF）作为一种临床高发的严重肝病，病程发展快，死亡率极高。

Acute liver failure ( ALF ) as a high incidence of severe clinical liver disease , it has rapid progression , high mortality rate .

方法采用D-gal诱导大鼠急性肝功能衰竭，诱导后24h，59只大鼠随机数字表法分成4组。

Methods AHF was induced by D-gal in SD rats . HcT was received 24 h after intoxication , and the AHF rats were divided into four groups randomly .

为了评价大鼠原位辅助性部分肝移植（APOLT）对急性肝功能衰竭的支持作用。

The models of both auxiliary partial orthotopic liver transplantation ( APOLT ) and acute liver failure were established .

目的观察急性肝功能衰竭时机体重要脏器eNOS及iNOS表达的变化，揭示其诱导产生的NO在急性肝衰多脏器功能障碍中的作用。

AIM To observe the expression change of eNOS and iNOS in the important organs of acute liver failure , and reveal the function of NO produced by these enzymes in multiple organs dysfunction .

FR-167653阻止肝硬化大鼠70%肝切除术后急性肝功能衰竭的实验研究

FR-167653 attenuates acute hepatic failure after partial hepatectomy in cirrhotic rats

方法D-氨基半乳糖（D-gal）诱发急性肝功能衰竭大鼠模型，造模动物随机分成5组：Ⅰ组生理盐水组；

Methods All the model rats of acute liver failure were induced by D-galactosamine and were divided into 5 groups at random 48 hours after drug induction : ⅰ .

目的：从分子和蛋白水平揭示在急性肝功能衰竭（ALF）时不同一氧化氮合酶（NOS）诱导产生的一氧化氮（NO）在肝、肺、肾脏和肠组织中表达的变化。

Objective : To observe the expression changes of nitric oxide synthase ( NOS ) in the liver , the lung , the kidney and the intestine of rat during acute liver failure ( ALF ) .

目的建立猪原位辅助性肝移植（APOLT）治疗急性肝功能衰竭的动物模型，并评价其治疗效果。

Objective To establish the model of auxiliary partial orthotopic liver transplantation ( APOLT ) and evaluate its supporting effect on acute liver failure .

目的探讨三七皂苷（PNS）对急性肝功能衰竭（AHF）大鼠肝脏修复的促进作用。

Objective To study the influence of panax notoginseng saponins ( PNS ) in all stages of acute hepatic failure ( AHF ) rats , and to investigate the PNS s promotion in AHF reparation .

目的探讨同种异体肝细胞腹腔移植联合肝再生增强因子（augmenterofliverregenration，ALR）对D-氨基半乳糖（D-gal）诱导的急性肝功能衰竭大鼠的治疗作用。

Objective To investigate the effect of allogeneic hepatocyte transplantation ( HcT ) plus augmenter of liver regenration ( ALR ) intraperitoneally on acute hepatic failure ( AHF ) induced by D-galactosamine ( D-gal ) in rats .

目的：评价我们改进的生物型人工肝系统（BALS）治疗急性肝功能衰竭犬的有效性和安全性。

Objective : To evaluate the safety and efficacy of the hollow fiber bioartificial liver system in canines with acute liver failure .

方法：应用3型鼠肝炎病毒（MHV-3）感染Balb/cJ小鼠制备急性肝功能衰竭模型。

Methods : Balb / cJ mice were infected by murine hepatitis virus-3 ( MHV-3 ) to establish the model of acute hepatic failure .

研究背景：既往研究表明，本研究室所建立的猪肝细胞型生物型人工肝脏支持技术（BALSS），在治疗急性肝功能衰竭模型犬和肝功能衰竭病人中取得了良好的肝功能支持作用；

Background : It has been proved that biological artificial liver support system ( BALSS ) with porcine hepatocytes has good liver support function in the treatment of dog and patients with acute hepatic failure .

急性肝功能衰竭大鼠模型血液灌流致死因素的分析

Analysis on death causing factors after hemoperfusion in fulminant hepatic failure rats

急性肝功能衰竭时肠粘膜屏障损伤的研究

Studies on intestinal mucosa barrier injuries in acute hepatic failure

枯否细胞功能状态对实验性急性肝功能衰竭的影响

Studies on actions of functional status of Kupffer cells on

大鼠外科型急性肝功能衰竭与多脏器功能衰竭

Surgical fulminant hepatic failure and multiple organic failure in rat

急性肝功能衰竭时自由基的意义及作用地位的实验研究

Studies on the significance of free radicals in experimental fulminant hepatic failure

肝细胞生长因子基因对肝细胞增殖及抗损伤能力的影响和对急性肝功能衰竭的治疗作用

Effects of hepatocyte growth factor on hepatocytes and model of acute liver failure

人胎肝细胞液对大鼠实验性急性肝功能衰竭的治疗作用

Effects of Human Fetal Liver Cytosol on Experimental Acute Hepatic Failure in Rats

腹腔肝细胞移植治疗大鼠急性肝功能衰竭

Effect of hepatocytes transplantation through abdominal injection in rats with acute liver failure

四氯化碳诱导大鼠急性肝功能衰竭动物模型的建立

Establishment of animal model with acute hepatic failure caused by lavage carbon tetrachloride