变形链球菌

变形链球菌不仅是冠部龋病的主要致病菌，也是根部龋的主要致病菌。

Streptococcus mutans is not only the crown caries pathogen , but also the root caries pathogen .

目的：观察不同糖源对变形链球菌（变链）生长产酸的影响。

Objectives : To evaluate the effect of different carbohydrates in the broth on the acidogenicity of the Streptococcus mutans isolates .

框内缺失突变法构建变形链球菌comE基因突变株

Construction of Streptococcus mutans comE Mutant Strain Using In-frame Deletion System

目的通过蜂胶口胶对变形链球菌、牙菌斑及唾液pH值的影响，初步探讨蜂胶口胶的防龋作用与机理。

The preventive effect and mechanism of propolis on caries were studied .

同一口腔中c血清型变形链球菌高、低毒力株的筛选

Isolation of high and low virulent strains of Streptococcus mutans of serotype c from the same oral cavity

变形链球菌；荧光定量PCR；唾液；

Streptococcus mutans ; Fluorescent quantitation PCR ; Saliva ;

目的快速、高效分离高质量变形链球菌RNA。

Objective To isolate high quality RNA from S. mutans efficiently .

目的：构建c血清型变形链球菌抑龋相关基因的抑制消减文库，为变形链球菌抑龋基因的筛选奠定基础。

Objective : To construct a suppression subtractive library of suppression-related genes from c serotype Streptococcus mutans ( S.mutans ) .

随意引物PCR法鉴别口腔变形链球菌的初步研究

Primary Study of Identification and Classification of Streptococcus Mutans by Arbitrary Primer Polymera Chain Reaction

套式PCR检测唾液中变形链球菌及远缘链球菌

Rapid detection of Streptococcus mutans and Streptococcus sobrinus in human saliva by nested polymerase chain reaction

变形链球菌表面蛋白V区、P区及C末端遗传多态性与龋病发生关系的研究

Relationship of the Genetic Diversity within the V-region , P-region and C-terminus of Surface Protein of Streptococcus mutans to Dental Caries

结果观察组使用蜂胶口胶后变形链球菌数量显著减少，牙菌斑指数降低，唾液pH值高于对照组。

Results Propolis gum significantly reduced the plaque index , the numbers of SM , and raised the salivary pH .

等离子体诱变筛选降解高浓度对苯二酚的突变株及其降解特性研究框内缺失突变法构建变形链球菌comE基因突变株

Study on the Selection of the Mutants by Plasma Mutation and Its High Hydroquinone Degradation Character Construction of Streptococcus mutans comE Mutant Strain Using In-frame Deletion System

目的：对不同粘附力变形链球菌临床分离株表面蛋白V区、P区编码基因进行序列测定。

Objective : To sequence V-region and P-region gene of surface protein of serotype c Streptococcus mutans clinical isolates with different adherent abilities .

目的对固定矫治器粘结前后牙颊面菌斑pH值和变形链球菌附着量、比例进行研究，初步探讨固定矫治中菌斑微生态的变化。

The purpose of this study was to evaluate the changes in pH , microbial populations of streptococcus mutans before and after bonding .

酸性环境下唾液分泌型IgA对变形链球菌免疫反应的体外研究

The study of salivary - SIgA reaction to Streptococcus mutans in acid environment

质粒pBR322介导的变形链球菌染色体DNA基因转化研究

Genetic transformation of streptococcus mutans chromosomal DNA by plasmid pBR322

变形链球菌表面蛋白pac基因A区片段在减毒鼠伤寒沙门氏菌的表达

Expression of Streptococcus mutans pac Gene Region A in Attenuated Salmonella typhimurium

变形链球菌密度感应CSP信号肽的固相合成和鉴定

The synthesis and appraisement of quorum sensing CSP signaling peptide of Streptococcus mutans

方法在厌氧培养条件下培养各株变形链球菌，用OD值测量法计算粘附量。

Methods The adherence amount was measured by OD reading after anaerobic incubation .

变形链球菌表面蛋白遗传多态性与龋病发生关系的研究Ⅱ表面蛋白V区、P区编码基因序列的测定

Relationship between genetic diversity of surface protein of Streptococcus mutans and dental caries . ⅱ Sequence of V-region and P-region gene of surface protein of Streptococcus mutans

结果：高龋组变形链球菌临床分离株的生物膜厚度和细菌分布密度显著高于无龋组（P0.05）；

RESULTS : The biofilm thickness and bacterial density in caries-active group were significantly higher than that in caries-free group ( P0.05 );

变形链球菌耐氟株质子移位ATP酶活性的体外研究

Effects of Fluoride and pH on Proton translocating Membrane ATPase Activity of Fluoride resistant Streptococcus mutans in vitro

PAGE银染法显示变形链球菌AP-PCR指纹图的可行性研究

PAGE-AgNO_3 staining displays AP-PCR fingerprint of mutans streptococci

结果：CPP对变形链球菌和远缘链球菌无直接抑菌作用。

Result : CPP had no inhibitory effect on bacteria .

变形链球菌mutans表面蛋白P1对人唾液接受器研究

Study on the Human Salivary Acceptors of Streptococcus mutans MT_6R Surface Adhesin P1

特异性IgY抗体对人牙菌斑中变形链球菌的影响

Effects of Specific IgY on Mutans Streptococci in Dental Plaque

IgY牙膏对口腔变形链球菌的抑制作用

The inhibitive effect of IgY toothpaste against oral Streptococcus mutans

结论蜂胶口胶抑制变形链球菌的生长繁殖，影响牙菌斑的形成，并升高唾液pH值，在龋病的预防上有开发价值。

Conclusion Propolis gum can depress the growth of SM and development of plaque , increase the pH value in saliva , and is usefull in preventing caries .

目的观察和探讨洗必泰涂料对正畸儿童牙面菌斑中细菌总数和变形链球菌数的影响，以及唾液pH值的改变。

Objective To evaluate the effect of chlorhexidine varnish on Streptococcus mutans and total bacterial count in dental plaque of orthodontic children , and the changes of salivary pH.