卵巢早衰

结论某些卵巢早衰患者的致病机理可能与45，X/46，XX嵌合核型比例增高，X染色体数量不足有关。

Conclusions This study indicated that some POF patients may attribute to low level 45 , X / 46 , XX mosaicism .

结果：单因素条件Logistic回归分析显示婚姻状况、人工流产次数等14个变量与卵巢早衰的发生有关；

Results : The single-factor conditional logistic regression analysis indicated that marriage condition , the times of induced abortion and another 12 factors were related to POF .

卵巢早衰患者血清抑制素B水平的改变

Serum levels of inhibin B are altered in premature ovarian failure

X染色体异常及其基因缺陷在卵巢早衰发病机制中的研究

The abnormality and genetic disorders of X chromosome involved in premature ovarian failure

目的：探讨卵巢早衰（Prematureovarianfailure，POF）的病因及诊断和治疗的方法。

Objective : To discuss the etiology , diagnosis and treatment of premature ovarian failure ( POF ) .

结论：本文的研究结果提示X染色体长臂末端可能是卵巢早衰的特异性基因区段并与X染色体末端端粒的缺失有关。

Conclusion : The result showed that terminal deletion of Xq and telomeric deletion of X chromosome were important factors of premature ovarian failure .

一旦原始卵泡闭锁或消耗过快，便会引发卵巢早衰（Prematureovarianfailure，POF），导致内分泌失调和不孕症等。

Once the depletion and atresia of primordial follicles is too fast to cause premature ovarian failure , endocrine dyscrasia and infertility .

目的了解卵巢早衰（Prematureovarianfailure，POF）患者的临床特征及治疗现状，以指导临床对POF的诊治。

Objective To explore clinical features and current treatment status in Chinese women with premature ovarian failure ( POF ) .

应用体外受精与胚胎移植（IVF－ET）技术为卵巢早衰患者及遗传病夫妇提供赠卵、赠胚胎治疗的方法；

By IVF ET technique oocyte / embryo donation therapy for the patients who are suffering from premature ovarian failure and genetic diseases .

目的探讨性激素替代疗法（HRT）在治疗卵巢早衰（Prematureovarianfailure，POF）中的作用以及POF的促排卵方案。

Objective To evaluate hormone replacement treatment ( HRT ) in patients with premature ovarian failure ( POF ) and explore the effective inducing ovulation protocol .

结论卵巢早衰是一种多因素引起的疾病，治疗较困难，性激素替代治疗可使临床症状缓解，血清FSH、LH明显降低。

Conclusion Premature ovarian failure is a disease of multifactors , HRT can improve symptoms and decrease the level of serum FSH and LH .

卵巢早衰GDF-9B基因结构的PCR-SSCP分析

PCR-SSCP analysis of GDF-9B gene in premature ovarian failure

结论：赠卵IVF-ET是一种妊娠率较高的助孕技术，适用于卵巢早衰，常规IVF-ET失败者。

Conclusion : Ooocyte donation IVF-ET is an effective treatment option for the infertile couples with ovarian failure or repeated unsuccessful trial of assisted reproductive technology .

糖皮质激素治疗不同时期实验性自身免疫性卵巢早衰T淋巴细胞亚群与MIF在自身免疫性卵巢早衰中的临床意义

Treat the Experimental Autoimmune Premature Ovarian Failure in Different Timing with Glucocorticoids The Clinical Significance of T Lymphocyte Subset and MIF in the Auto-immunity of POF

卵巢早衰组在A型行为的各项积分（TH、CH、TH+CH）得分，均较正常对照组高，两组之间的差异有统计学意义（P0.05）。

The premature ovarian failure in type A behavior of the integral ( TH , CH , TH + CH ) score , were compared to normal controls , the difference between the two groups was statistically significant ( P0.05 ) .

目的探讨卵巢早衰与低百分率45，X/46，XX嵌合核型的关系，了解荧光原位杂交（FISH）技术检测染色体嵌合核型的敏感性和特异性。

Objective To investigate whether low level 45 , X / 46 , XX mosaicism presents in women with premature ovarian failure ( POF ) and the sensitivity and specificity of fluorescent in situ hybridization ( FISH ) for detecting X chromosome mosaicism .

卵巢早衰（POF）是临床诊断中呈逐年上升趋势的妇科内分泌疾病，病因病机复杂，给患者带来了巨大的痛苦。

Premature ovarian failure is a gynecological endocrine disease which showed tendency to rise year by year in clinical diagnosis . The pathogeny and pathogenesis is complicated , it has brought great suffering to patients .

目的探讨左归丸对免疫性卵巢早衰（POF）小鼠生殖内分泌及抗卵巢抗体（AoAb）的影响。

Objective It is to explore the influence of Zuogui pill on reproductive endocrine and antiovarian antibodies ( AoAb ) in immune premature ovarian failure ( POF ) rats .

本文对96例卵巢早衰（POF）患者进行了病因探讨，经有关检查提示，家族倾向、染色体异常和卵巢发育不全导致原始生殖细胞数少或缺乏可能为POF的主要原因；

The etiological cause of 96 patients with premature ovarian failure was analyzed . The result suggested that the main cause of premature ovarian failure might be the deficiency or decrease in the number of primordial germ cells , which results from genetic disposition , chromosomal abnormalities and ovarian dysgenesis .

目的探讨卵巢早衰（POF）患者血清中抗卵巢抗体（AoAb）、抗透明带抗体（AZpAb）水平及其分类情况，研究免疫性卵巢早衰的发病机理。

Objective To study the level and classfication of anti-ovarian antibodies ( AoAb ) and anti-zona pellucida antibodies ( AZpAb ) in the sera of premature ovarian failure ( POF ) patients and to study the pathogenesis of POF .

未生育妇女卵巢早衰13例临床分析

The Clinical Analysis of 13 Nulliparous Women with Premature Ovarian Failure

前言：目的：探讨卵巢早衰的发病原因。

Objective : To explore the etiology of premature ovarian failure .

肿瘤治疗相关性卵巢早衰与功能重建研究进展

Development of tumor treatment-related premature ovarian failure and ovarian function reconstruction

自身免疫性卵巢早衰的诊断与治疗的研究

The Research on Clinical Diagnosis and Treatment of Auto-immunity of POF

经阴道多普勒超声检测卵巢早衰患者卵巢血流变化与卵巢激素水平的相关性

The Relation between Ovarian Blood Index and Hormone Level in POF

抑制素α基因与卵巢早衰的相关性研究

Association between the inhibin alpha gene and premature ovarian failure

卵巢早衰与卵子赠送22例分析

Premature ovarian failure and oocyte donation : a report of 22 cases

雌激素对化疗损伤性卵巢早衰保护作用的实验研究

Protective effect of estrogen against chemotherapy-induced ovarian damage in rats

结论左归丸可能具有改善免疫性卵巢早衰小鼠症状的作用。

ConclusionZuogui pill may have some prevention and treatment action on POF .

卵巢早衰影响因素病例对照研究的相关性分析

Analysis of the Factors Related to the Development of Premature Ovarian Failure