单体型

单体型是一些特定的DNA位点组成的序列。

Haplotype is the sequence of some special DNA sites .

单体型组装问题是利用个体DNA测序片段数据推出该个体一对单体型的计算问题。

The haplotype assembly problem is a computational problem that , given a set of DNA sequence fragment data of an individual , induces the corresponding haplotypes .

乙型肝炎疫苗免疫不应答与HLA基因单体型的相关性研究

The relationship between nonresponse to hepatitis B vaccine and HLA genotype / haplotype

家系分析表明：Y、X及V等位基因与HLA单体型连锁。

Family studies showed that the Y. X and V alleles were inherited and segregated with HLA haplotypes .

爱尔兰人群HLA单体型发病率在多发性硬化症患病率差异中的作用

Population frequency of HLA haplotypes contributes to the prevalence difference of multiple sclerosis in Ireland

染色体单体型分析及突变检测在Wilson病临床诊断中的应用

Clinical Application of Chromosome Haplotype Analysis and Mutation Analysis to the Diagnosis of Wilson 's Disease

寻找到一个HLA匹配供者的概率可以表示成供者数和HLA单体型频率的函数。结论找到HLA配合供者概率取决于骨髓库供者人数的多寡以及HLA单体型频率。

Conclusion The probability of finding HLA matched donor depends on the pool size and HLA haplotype frequencies .

HLAⅡ类单体型DRB11501与再生障碍性贫血

A HLA Class ⅱ Haplotype of DRB_11501 and Aplastic Anemia

方法根据HLA表型群体资料，使用最大数学预期值算法（Expectationmaximization，EM）计算HLA三座位单体型频率。

Methods Expectation-maximization ( EM ) algorithm was adopted to estimate HLA three-locus haplotype frequencies on the basis of HLA phenotype data .

实验表明：~3H-TdR或HTO照射S期，G2期淋巴细胞诱发染色体单体型畸变；

Chromatid-type aberration was induced by ~ 3H-TdR or HTO irradiation in S , G_2 phase of lymphocytes .

最大似然法和方根法计算HLA三座位单体型频率的比较单片机控制的微型集成锁相频率合成器

Comparison of EM and square root algorithms applied to estimate HLA-A-B-DR haplotype frequency Miniature Integrated PLL Frequency Synthesizer Controlled by Single Chip Microprocessor

方法在哈迪-温伯格群体中的HLA单体型频率可以从供者表型资料求得。

Methods Assuming a Hardy Weinberg equilibrium of underlying population , HLA haplotype frequencies were estimated from phenotype data in the donor pool .

许多研究表明在预测、研究复杂疾病方面，单体型所携带的信息比单个的SNP或基因型数据的信息多得多。

In disease association studies , the haplotypes have generally more information content than individual SNPs or genotypes .

本文分析了四川省10个p地中海贫血家系中β珠蛋白基因簇的限制性内切酶位点多态性和单体型，发现在20条携带β地中海贫血基因的染色体中存在11种单体型。

The restriction endonuclease site polymorphism and haplotype of the β globin gene cluster in 10 β thalassemia families in Sichuan province were analysed . Eleven haplotypes were revealed in 20 chromosomes carrying the β thalassemia gene .

双位点TDT提示单体型TG、CA与精神分裂症、心境障碍相关联（P<0.05）。

The results of two-site TDT test indicated haplotypes TG and CA were associated with schizophrenia or mood disorders ( P < 0.05 ) .

目的直接定量PCR结合STR单体型连锁分析，以便更准确检出缺失型家系中DMD基因携带者。

Objective : To detect DMD gene carriers in the deletion families accurately , using quantitative PCR technique and the linkage analysis of STR polymorphisms .

人类基因组单体型图（HapMap）测序联盟使用了来自四个测试人群的DNA创建这份目录，其中包括一个尼日利亚人群和一个中国人人群。

The HapMap consortium created their catalogue with DNA from four test populations , including a Nigerian group and a Chinese one .

基因组上的SNP位点及其相应单体型的信息已经广泛地应用于疾病易感基因定位和药物基因组学研究。

SNPs and haplotypes in the human genome have been widely used in the identification of disease-associated genes and the study of pharmacogenomics .

广州地区106例汉族人群MICA和MICB微卫星基因座单体型研究

The Study on the Haplotype of MICA and MICB Microsatellite Locus In Guangzhou Han Population

后者则使用EH病例对照样本，检测特定基因的遗传多态性及其组合（即单体型，haplotype）是否与EH或BP水平存在统计学关联。

This type of study is to examine the association of the polymorphisms and the haplotypes composed of these polymorphisms in certain genes with BP or EH .

而且，除G显带检测出的倒位类型外，又有两种类型的倒位，其中涉及到常规显带技术难以检测出的染色单体型倒位。

Moreover , besides the type of inversion diagnosed by G-banding , there are the two other abnormal karyotypes , including a type of chromatid inversion , which is difficult to be detected by conventional G-banding technique .

羧肽酶B消除C4副带后对湖北地区C4基因频率及家系C4单体型与补体型的检测

Reevaluation of the Frequencies of C4 Alleles , C4 Haplotypes and Complotypes in the Han Families of Hubei District After Removal of C4 Minor Bands by Carboxypeptidase B

基因型错误的影响也通过基于血管紧张肽转化酶（ACE）基因的10个SNPs单体型频率的模拟研究得到了证实。

The effects of the genotype errors are evaluated by a simulation study on the basis of the haplotype frequencies of 10 SNPs of ACE genes .

激肽释放酶&激肽系统基因相关SNPs及其单体型与长沙汉族人群脑出血的关系研究

The Study of the Association of SNPs and Haplotype of Genes Involved in the Kallikrein-kinin System with Cerebral Hemorrhage in Changsha Han Chinese

并且发现，在相同的辐照剂量下，添加聚合物型HALS的PE的黄度比添加相应的单体型HALS的PE的黄度低一些。

It is also found that polymeric HALS is more effective in preventing PE from radiation-induced discoloration than corresponding monomeric HALS when radiation dose is higher than200kGy .

Murci博士的数据来自人类基因组单体型计划图，旨在对单核苷酸多态性，即SNPs进行归类。

Dr Quintana-Murci 's data were drawn from a project called HapMap , which catalogues what are known as single-nucleotide polymorphisms , or SNPs .

T-T单体型可能是胃腺癌的遗传易感因素。

The haplotype T-T may be the genetic susceptible factor to gastric cancer .

荧光定量PCR技术可以定量测定个体携带的KIR基因的相对拷贝数，对于家系分析KIR单体型是一有益补充。

QPCR could be used to determine the copy numbers of KIR gene , and it was a helpful supplementary tool for certain KIR haplotype analysis .

基于家系和单体型的TIM-1及TIM-3基因多态性与变应性哮喘的关联研究

Family - and Haplotype-based Association Study of TIM-1 and TIM-3 Polymorphisms with Allergic Asthma

两多态性位点联合分析显示，ESCC、GCA患者与健康对照组的单体型分布也无显著性差异（均P0.05）。

When the two IL-10 SNPs were combined , the haplotype distribution between ESCC and GCA patients was not significantly different from that in healthy controls ( P0.05 ) .