乳果糖

并用带特殊电化学检测器的高压液相色谱法（HPLC）检测尿中乳果糖与甘露醇排泄率比值。以10名健康志愿者作为正常对照组。

The ratio of lactulose to mannitol in urine was detected by HPLC with Pulsed Electrochemical Detection .

乳果糖对肠道菌群及SIgA含量的影响

The effect of drinking lactulose on intestinal bacterial flora and SIgA

内毒素和乳果糖甘露醇比值在6h达高峰。

Urine lactulose / mannitol ratio and endotoxin content peaked at 6 h.

2肝硬化发生并发症的患者血清内毒素、乳果糖／甘露醇尿比值明显高于无并发症的患者（P0.05）。

The levels of endotoxin and urinary ratio of lactulose to mannitol in cirrhosis patients with complication were higher than those cirrhosis patients without complications ( P0.05 ) . 3 .

目的：探讨TACE后使用乳果糖溶液在改善患者腹部症状以及肝性脑病的作用。

AIM : To investigate the effect of lactulose on alleviating abdominal symptoms and encephalopathy after transcatheter arterial chemoembolization ( TACE ) in hepatocellular carcinoma ( HCC ) .

方法：用高压液相色谱法检测尿乳果糖／甘露醇比值，放射免疫分析法测定血中IgM、IgA、IgG含量及T细胞亚群CD4、CD8、CD4／CD8比值。

Methods : Determination of lactulose and mannitol ratio in urine by high performance liquid chromatography and measurement IgM 、 IgA 、 IgG 、 CD4 、 CD8 、 CD4 / CD8 in blood .

结果1肝硬化组血清内毒素、乳果糖／甘露醇尿比值、肠杆菌、葡萄球菌和梭菌较健康组明显升高，肠双歧杆菌和乳杆菌明显降低（P0.05）。

Endotoxin level , urinary ratio of lactulose to mannitol , Enterobacter , Staphylococcus aureus and Clostridium of cirrhosis group were significantly higher than the healthy group , while Bifidobacterium , Lactobacillus were lower than the healthy group ( P0.05 ) . 2 .

温度在98℃，采用6mg/ml的催化剂填料，反应60min就可以获得乳果糖的最佳产品。

Optimal production of lactulose was reached at 98 ℃, employing 6 mg / ml of catalyst loading within 60 min of reaction .

乳果糖组肠道G-杆菌菌量、肠内容物内毒素含量、血内毒素和ALT水平均明显低于肝损伤组（P<0.05）。

However , the levels of endotoxin , TNF and ALT in blood , the bacteria counting and endotoxin levels of intestinal contents in group B were markedly lower than that in group A ( P < 0.05 ) .

结论老年便秘口服乳果糖溶液起始剂量以15～30ml／d为宜。

Conclusions The initial dosage of lactulose solution for elderly constipation is 15 to 30 ml per day depending on the severity of constipation .

目的：观察早期肠内营养（EN）联合肠道去污（SDD）对犬急性坏死性胰腺炎（ANP）肠黏膜结构、尿中的甘露醇/乳果糖的影响。

Objective : To evaluate the effect of early enteral nutrition ( EN ) and selective decontamination of the digestive tract ( SDD ) on the structure of the gut and the urine lactulose / mannitol ratio in dogs with acute necrotizing pancreatitis .

乳果糖缓解梗阻性黄疸并发症的动物实验研究

Animal experimental study of preventing complications with lactulose in obstructive jaundice

乳果糖加双歧口服液灌肠治疗肝性脑病的效果观察

Lactulose plus Bifidobacterium Solution Enema in the Treatment of Hepatic Encephalopathy

利用分光光度法能准确快速地测定乳果糖浆中乳果糖的含量。

The lactulose could be quickly quantified by this spectrophotometric method .

乳果糖治疗肝性脑病和亚临床肝性脑病149例临床观察

Lactulose in 149 cases of hepatic encephalopathy and subclinical hepatic encephalopathy

目的观察乳果糖对老年便秘的疗效。

Objective To observe the curative effect of lactulose in elderly constipation .

乳果糖对白细胞介素-18介导肠黏膜屏障的影响

Effect of lactulose on interleukin-18 mediated barrier of intestinal mucosa

乳果糖治疗亚临床肝性脑病不同疗程的疗效观察

Efficacy of lactulose in different courses for patients with subclinical hepatic encephalopathy

离子色谱电化学测定牛奶中的乳糖和乳果糖反相离子对色谱-脉冲安培电化学法测定硫酸庆大霉素中各组分含量

Determination of Lactose and Lactulose by Ion Chromatography with Pulsed Amperometric Detection

我们可以继续输血输乳果糖。

We can continue the transfusions and the lactulose .

乳果糖对恶性梗阻性黄疸内毒素血症影响的研究

The Study of Influence of Endotoxemia in Malignant Obstructive Jaundice Patients by Oral Lactulose

功能性肠病病人乳果糖氢呼气试验结果分析

Analysis of Results of Lactulose Hydrogen Breath Test in Patients with Functional Bowel Disorders

乳果糖溶液对老年便秘158例疗效观察

Observation on the effect of Lactulose solution in 158 cases of elderly constipation patients

应用乳果糖能部分逆转肝脏功能和结构的病理改变。

The application of lactulose could partially alleviate all these pathological changes noted above .

上用示差检测器测定尿液中乳果糖和甘露醇的浓度。

The urinary concentrations of lactulose and mannitol were determined by a refractive index detector .

结论雅博司联合乳果糖治疗慢性重型肝炎合并的肝性脑病，疗效显著，值得研究和应用。

Conclusion Hepa-Merz is effective in treating patients with hepatic encephalopathy from chronic severe hepatitis .

结论乳果糖溶液对人体具有明显通便功能，且对机体健康无不良影响。

Conclusion Lactulose solution could improve human feces excretion function and had no negative effects .

乳糖异构化制备乳果糖的研究

Study on Lactose Isomerisation to Lactulose

乳果糖对临床及亚临床肝性脑病预防作用的实验研究

Experimental Study of Prophylactic Effect of Lactulose on Hepatic Encephalopathy and Sub - clinical Hepatic Encephalopathy

乳果糖对肝硬化自发性腹膜炎患者肠黏膜屏障功能的影响

The Clinical Effect of Lactulose on Intestinal Barrier Function in Cirrhosis Patients with Spontaneous Bacterial Peritonitis