乳腺良性肿瘤

目的探讨Survivin基因在乳腺良性肿瘤、乳腺癌组织中表达的临床意义及其与血管内皮生长因子（VEGF）表达的关系。

Objective To investigate the expression and the clinical significance of Survivin and VEGF in benign and malignant breast tumors .

配对Logistic回归分析结果表明：既往有乳腺良性肿瘤史及常吃香肠是乳腺癌发生的主要危险因素；

The results of matched logistic regression analysis showed that the history of breast benign tumor and often taking the sausage were the major risk factors .

非典型增生组织和乳腺良性肿瘤组织组织中COX-2高表达者其癌变的几率可能比COX-2低表达者高。

The breast atypical hyperplasia and benign tissues with higher expression of COX-2 maybe have higher risks to developing to malignant tissues than them with lower COX-2 expression .

我们测定了327例30岁以上健康妇女的FT4I值，测定了124例（30岁以上女性）乳腺良性肿瘤患者和乳腺癌患者的FT4I值。

FT_4 I values were measured in 327 healthy women over 30 years of age and in 124 patient ( female over 30 ) with benign breast tumor or breast cancer .

目的探讨治疗乳腺良性肿瘤新的手术方法。

Objective To evaluate a new incision for excision of benign breast tumour .

另取10例对照标本，为其他乳腺良性肿瘤患者经手术切除后的组织冰冻标本。

Other 10 frozen tissues of benign breast tumor were obtained as control .

10例乳腺良性肿瘤组织标本同样测序作为对照。

Other 10 samples of benign breast tumor were also sequenced as controls . 3 .

乳晕小切口治疗乳腺良性肿瘤：附548例报告

Periareolar incision in treatment of benign tumor of breast : a report of 548 cases

门诊乳腺良性肿瘤手术病人换药间隔时间的研究

A study on interval time of changing dressing for outpatients with benign breast tumor underwent operation

【中英文摘要】目的探讨手术治疗乳腺良性肿瘤的最佳切口选择。

Objective To exploration the selection of the best incision for operative treatment of benign breast tumor .

乳腺良性肿瘤切除术中保留残腔与缝闭残腔的临床疗效对比

Clinical effective comparison between the preserving residual cavity and closing residual cavity in breast benign tumor resection

12例乳腺良性肿瘤及正常乳腺组织表达水平分别为0.908±0.047、0.934±0.038；

12 benign breast tumors and 12 normal breast tissue were 0.908 ± 0.047 、 0.934 ± 0.038 respectively .

目的探讨乳腔镜微小隐蔽切口切除乳腺良性肿瘤的可行性及临床疗效。

Objective To investigate the feasibility and effect of mastoscopic extirpation of benign breast masses by small and concealing incision .

这些特征不但反映乳腺良性肿瘤和恶性肿瘤本质的区别，还考虑到医学超声图像为相干图像的特点。

These features not only reflect the essential differences between malignant breast tumors and benign tumors , but also concern about the characters of ultrasound images as the coherent images .

结果病理诊断乳腺良性肿瘤229例，乳腺恶性肿瘤29例，其中浸润性导管癌19例，髓样癌7例，硬癌2例，炎性癌1例。

Results Pathological examination showed that of the 258 cases , there were 229 cases of benign mammary tumor , 29 malignant mammary tumor ( 19 invasive and intraductal carcinoma , 2 scirrhus and one inflammatory carcinoma ) .

浸润性小叶癌和浸润性导管癌MMP鄄2的阳性率达86.7%，明显高于恶性程度较低的黏液腺癌和髓样癌（20.0%）以及乳腺的良性肿瘤（13.3%）。

MMP-2 was positive in 86.7 % cases with invasive duct and lobular carcinoma , which was much higher than that in mucinous carcinoma ( 20.0 % ), medullary carcinoma 20.0 % , and other benign disease ( 13.3 % ) .

方法对124例乳腺良性小肿瘤及恶性小肿瘤患者分别行常规及高频超声检查，并与手术及病理检查结果对照，分析两者不同的声像改变。

Methods Overall , 124 cases of small benign or malignant breast tumors were examined by ultrasound and the results were compared with the surgical and pathological findings .

发现正常乳腺和良性乳腺肿瘤AR显著低于乳腺癌（P<0.05）。

AR of normal breast tissues and benign breast neoplasms was significant lower than that of breast cancer ( P < 0.05 ) .

条件Logistic回归分析显示初潮年龄早、乳腺良性疾病史、肿瘤家族史及流产次数多是乳腺癌的危险因素，而哺乳和饮用井水是保护因素。

In conditional logistic regression model , early age at menarche , history of benign breast diseases , family history of carcinoma , high frequency of abortion are risk factors , while breast feeding and drinking well water are protective factors .

结果发现：1）PTEN蛋白在正常乳腺组织和良性乳腺肿瘤高表达率为100%，在恶性乳腺肿瘤组织中的高表达率为67%（8/12），两者比较差异极显著（P<0.01）；

The over-expression rate of PTEN protein was100 % in normal and well-differentiated mammary gland tissues and67 % in breast cancer cases respectively with a significant difference between the two groups ( P < 0.01 ) .

用同步辐射X射线荧光（SR-XRF）技术分析了正常乳腺组织、良性乳腺肿瘤组织和乳腺癌组织中微量元素的种类、相对含量等。

The variation of relative contents of some typical trace elements in normal breast tissues , benign breast tumor tissues and breast cancer tissues is studied by the synchrotron radiation X-ray fluorescence ( SR-XRF ) technique .

结果钼靶摄影对乳腺良性疾病、恶性肿瘤和早期乳腺癌的诊断符合率分别为93.10%、93.75%和78.13%，而近红外扫描分别为72.41%、73.44%和57.81%。

Results : The diagnostic accuracy rate of mammography about benign breast lesions , breast tumors and early breast cancer were separately 93.10 % , 93.75 % and 78.13 % , and that of near infrared light scanning 72.41 % , 73.44 % and 57.81 % .

结果①乳腺癌患者与乳腺良性肿瘤患者术前外周血中CD3+、CD4+、CD8+、NK细胞的百分比、CD4+CD8+比率均在正常范围，两组比较无显著差异（P>005）；

Results ① There were no difference on the percentages of CD3 + , CD4 + , CD8 + , NK cells and the rates of CD4 + / CD8 + between early breast cancer patients and benign breast tumour patients ( P > 0.05 ) .

应用免疫组织化学方法测定Livin在人乳腺癌组织与乳腺良性肿瘤、癌旁乳腺组织的表达。结果：①Livin在4株乳腺癌细胞株中的表达明显高于乳腺上皮细胞株（P0.05）。

Immunohistochemistry was applied detect the expression of Livin in human breast cancer , benign tumor and tumor-adjacent tissues . Results : ① Livin expression of the breast cancer cells were obviously higher than those of breast epithelial cell ( P0.05 ) .

方法选用10例正常乳腺组织、30例乳腺良性肿瘤及60例乳腺恶性肿瘤标本，以免疫组织化学及半定量反转录PCR（RT-PCR）检测VEGF-C的表达。

Methods Protein and mRNA of VEGF-C in 10 cases of normal breast tissue , 30 cases of benign breast tumor and 40 cases of malignant breast tumor were detected by immunohistochemistry staining or half-quantity RT-PCR .

利用显微图象分析技术对75例乳腺癌，6例乳腺良性肿瘤及11例乳腺结构不良进行了细胞形态定量研究。

Six morphometric parameters of 75 cases with breast carcinoma , 6 cases of benign breast tumors and 11 cases of mammary dysplasia were analysed using micro-image analysis system .

结果：bag1在乳腺癌组织中，乳腺良性肿瘤中，正常乳腺组织中阳性表达率分别为85.0%，10.0%和10.0%，差异明显（P<0.05）。

RESULTS : The positive rate of bag 1 expression among breast cancer , benign tumor and normal tissues were 85.0 % , 10.0 % and 10.0 % respectively and significant difference was observed ( P < 0.05 ) .

结果：COX-2在乳腺癌组织、非典型增生组织、乳腺良性肿瘤组织的表达与正常组织相比显著升高（P0.0001、P0.001、P0.01），COX-2在癌组织的表达比良性肿瘤组织高，P0.05。

RESULTS : The expressions of COX-2 in breast cancer tissue , atypical hyperplasic tissue and breast benign tumor tissue were higher than that in normal breast tissue ( P0.000 1 , P0.001 , P0.01 ) .

因此，Ⅲ级乳腺浸润性非特殊型癌可能与乳腺良性肿瘤的X线表现类似。

Therefore , high-grade non-special type invasive carcinoma may display imaging features as similar as the benign breast cancer .

妊娠合并乳腺巨大纤维腺瘤临床罕见，需与妊娠期乳腺良性肿瘤如泌乳型腺瘤及妊娠合并乳腺恶性肿瘤如乳腺叶状囊肉瘤、乳腺癌等鉴别。

Giant fibroadenoma in pregnancy is rare , and it needs to be distinguished with benign or malignant tumor in pregnancy such as lactating adenoma , breast cancer and cystosarcoma phylloides .