巴比妥钠

利福霉素B发酵过程中巴比妥钠加量的优化

Optimization of Barbital Sodium Content during Fermentation of Rifamycin B

结论PH指示剂吸收度比值测定巴比妥钠的含量是一种切实可行的方法。

Conclusion It is a practical method to determine content of Barbital Sodium by PH Indicator Absorptance Method .

巴比妥钠对铝合金在NaCl溶液中缓蚀作用的研究

Inhibition effect of sodium barbital on aluminium alloy in 3.5 % nacl solution

目的为探讨PH指示剂吸收度比值法和银量法测定巴比妥钠含量的优劣。

Objective To Study the better one between PH indicator absorptance method and Ag ration method to determine content of barbital sodium .

方法SD大鼠经10%戊巴比妥钠麻醉后，开胸结扎冠脉左前降支，建立大鼠AMI模型。

Methods Left anterior descending coronary arteries were ligated in SD rats after anesthesia by 10 % pentobarbital sodium .

材料和方法：健康雄性SD大鼠48只，3%戊巴比妥钠（30mg/kg）腹腔内注射麻醉，麻醉成功后肌肉注射阿托品0.04me/kg。

Materials and Methods : Forty-eight male Sprague-Dawley rats were anesthetized with an intraperitoneal injection of sodium pentobarbital ( 30mg / kg ) .

TA对异戊巴比妥钠诱导的睡眠时间无延长作用，在高架十字迷路中与乙醇不发生相互作用；

TA did not produce the influence on amobarbital sodium sleeping and had no interaction with ethanol in the elevated plus-maze test .

标本收集和实验室检查：于妊娠第21天在戊巴比妥钠（50m留kg）麻醉下，剖宫取胎，记录胎仔体重，身长；

Specimen collections and laboratory check ; In the 21 days of pregnant rats , infants were taken which registered weight and height after aesthesia .

100mg/kgCAD组还可显著延长巴比妥钠催眠潜伏期（P<0.01），并缩短其睡眠时间（P<0.01）。

100 mg / kg of CAD was shown to significantly prolonged the latent period ( P < 0.01 ) and shortened the duration of hypnosis ( P < ( 0.01 )) induced by barbital sodium .

用3%戊巴比妥钠腹腔内注射麻醉（30mg／kg.b.w）。

Anesthesia was performed with injection of 3 % pentobarbital ( 30mg / kg . b.w ) into abdominal cavity .

方法采用摇瓶发酵，优化巴比妥钠初始含量及中间补加策略，通过测定发酵液中利福霉素B的效价及菌体浓度来确定合适的发酵工艺。

Methods In shaken flask culture , the content and feeding strategy of barbital sodium during the fermentation of rifamycin B was optimized and the suitable fermentation technology was also defined by determining the potency of rifamycin B and PMV of mycelia in fermentation broth .

结果表明以pH8.1、0.06M巴比妥钠-HCl缓冲液，1%琼脂糖，孔径和孔距均为3mm，效果最佳。

It was shown that 3 mm of well diameter and distance and 1 % agarose yielded best results .

目的研究越桔提取物（BEP）对戊巴比妥钠所致小鼠学习记忆获得障碍的影响。

Objective To study the effects of BEP on impairment of learning and memory in mice induced by sodium pentobarbital .

在戊巴比妥钠麻醉兔中，记录股动脉血压，心率（HR）和肾交感神经活动（RSNA）。

The femoral arterial pressure , heart rate ( HR ) and renal sympathetic nerve activity ( RSNA ) were recorded in pentobarbital anesthetized rabbits .

目的观察独活香豆素组分（TCA）对戊巴比妥钠及巴比妥钠催眠作用的影响。

Objective To observe the influence of the coumarins from Radix Angelicae pubescentis ( TCA ) on the hypnotic effects of pentobarbital sodium and barbital sodium .

目的观察普乐林（PRN）对小鼠戊巴比妥钠催眠作用的影响。

Objective : To observe the influence of puerarin ( PRN ) on the effect of pentobarbital sodium in mice .

结果：氯霉素组和3个剂量的CAD组均可使戊巴比妥钠睡眠时间延长，分别延至溶媒对照组的380%、284%、353%和366%（P<0.01）；

Results : The duration of hypnosis induced by pentobarbital sodium was prolonged by 380 % , 284 % , 353 % and 366 % ( P < ( 0.01 ),) respectively , in mice given chloromycin and three different doses of CAD .

方法12头猪，戊巴比妥钠（≤30mg/kg·b.w.）

Methods Twelve pigs were anaesthetized with sodium pentobarbital (≤ 30 mg / kg · b.w. )

3%戊巴比妥钠（1ml／kg）腹腔注射麻醉，常规消毒铺巾，显露L（1-3）棘突及椎板，显露硬膜。

The rabbits were injected 3 % nembutal ( 1mg / kg ) intraperitoneally . Secondly , cut L_ ( 1-3 ) spinous process and lamina of vertebra to expose dura .

绞股蓝皂甙SH－6（GynosaponinSH－6）可抑制小白鼠自发性活动，增加戊巴比妥钠催眠阈下剂量的睡眠率和延长其催眠剂量的睡眠时间。

Intraperitoneal injection ( ip ) of gynosaponin SH-6 inhibited the spontaneous motion , enhanced the asleep rate ( subthreshold doses ) and prolonged the asleep time ( superthreshold doses ) of sodium pentobarbital in mice .

方法：采用小鼠水迷宫行为实验法，检测SSF对东莨菪碱、戊巴比妥钠引起小鼠学习、记忆障碍的作用。

Methods : The mice water maze performance was used to evaluate the effects of SSF on learning and memory deficits of mice induced by scopolamine and carbrital .

结论：Ipt对戊巴比妥钠麻醉正常血压狗有轻度的降低血压作用，对心脏泵血功能有轻微抑制作用。

Conclusion : Ipt has mild hypotensive effect in anaesthetized normotensive dogs , and slight inhibition on cardiac pumping function at the dose of 0 . 25 - 0 . 5mg · kg-1 .

结果：YZR能抑制小鼠自发活动，与戊巴比妥钠合用有协同作用。

Results : This oral liquid could reduce the spontaneous activity and cooperate with pentobarbital sodium to increase sleep time of mice .

连续给药6d后，观察戊巴比妥钠的催眠作用，并检测小鼠肝脏系数和肝微粒体细胞色素P450（CYP）的含量变化。

After given with SMI for six days , the hypnotic effect of pentobarbital sodium , liver index and the total contents of microsomal cytochrome P450 ( CYP ) were examined at the last administration 24h later .

电针组在戊巴比妥钠麻醉下根据组别分别用2/5Hz，2/15Hz或2/100Hz频率的疏密波刺激百会穴，30min/d，共5d。

The other three groups received electroacupuncture with 2 / 5 Hz , 2 / 15 Hz or 2 / 100 Hz respectively at the Baihui acupoint 30 minutes a day for 5 days under pentobarbital sodium anesthesia .

方法Langendorff离体心脏灌流装置制备戊巴比妥钠心衰模型，八道生理记录仪测定不同浓度Str对心功能的影响，无机磷法测定各组心肌细胞膜Na+，K+ATP酶活性。

METHODS Langendorff isolated heart failure models made by perfusing heart with K-H solution containing sodium pentobarbital . Eight-channel physiological recording instrument was used to determine cardiac function . Colorimetry method was used to determine cardiac sarcolemmal Na + , K + - ATPase activity .

结果TFSB（30~300mg·kg-1）不影响自发活动，对戊巴比妥钠诱导睡眠时间和睡眠潜伏期无明显影响，对肌肉协调能力和运动协调能力没有显著影响（没有肌肉松驰作用）。

Results : TFSB ( 30 ~ 300mg · kg-1 ) produced neither influence on latency time and sleeping time induced by Pentobarbital sodium and spontaneous activity nor muscle and motor coordination ( no relaxing muscle ) .

按Bennett法，大鼠腹腔注射戊巴比妥钠40mg/kg后，假手术组暴露右侧坐骨神经不结扎，慢性坐骨神经挤压损伤组在该神经主干部位，用4-0铬制羊肠线松结扎4道。

After phenobarbital sodium 40 mg / kg was injected into abdominal cavity of all the rats by Bennett method , the rats in CCI group were placed with four loose 4 - 0 chromic catgut ligatures around the nerve shaft of the right sciatic nerve ;

模型制作：采用2%戊巴比妥钠溶液（0.1mL/50g）经腹膜腔注射麻醉后，显露并切去鼠的右侧坐骨神经一段使形成10mm缺损。

Modeling : The rats were anesthetized by intraperitoneal injection of 0.1 mL / 50 g pentobarbital solution ( 2 % ) in each groups , and their right sciatic nerves were exposed in the mid-thigh region to produce a 10 mm defect .

用戊巴比妥钠静脉注射制作大急性心力衰竭模型，然后静脉注射0.5g/ml的暖心液0.5ml/kg，观察暖心液对心衰犬血液动力学的影响。

The effects of oral liquor for warming heart ( 0 . 5ml / kg iv ) on hemodynamics were studies in dogs with experimental acute heart failure induced by intravenous pentobarbital sodium .