启动子
- promoter
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在基因表达中,启动子作为一段提供RNA聚合酶识别和结合的DNA序列,启动基因的转录。
As segment , promoter provides recognition and combination sequences for RNA polymerase for activating gene translation .
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其启动子可以驱动报告基因GFP在斑马鱼胚胎骨骼肌以及心肌中特异性表达。
Its promoter can drive reporter gene-GFP in skeletal and cardiac muscles in zebrafish embryos .
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我们正在研究基因启动子以及什么会是它们的主开关。
We 're looking at gene promoters and what would be their master switch .
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乙型肝炎病毒C基因启动子热点变异的检测及分析
Detection and analysis of core promoter mutation of hepatitis B virus
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乙型肝炎病毒基本核心启动子及前C区突变与基因型的关系
Relationship between hepatitis B virus basic core promoter / precore mutations and viral genotypes
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已经证明两种GAP基因的上游区具有启动子活性。
The upstream sequences of both genes were shown to have promoter activity .
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目的:探讨双启动子DNA疫苗载体在减毒沙门菌中的稳定性和重组减毒沙门菌在小鼠体内的定植及动态变化。
Objective : To evaluate the stability and colonization of the Salmonella-based Dual-promoter DNA vaccine in vivo .
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转录因子是指能够与真核基因启动子区域中顺式作用元件发生特异性相互作用的DNA结合蛋白。
Transcription factor is the DNA-binding protein which specifically interacted with cis-acting elements in the promoter region of eukaryotic gene .
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从带烟草花叶病毒外壳蛋白亚基因组启动子的负链RNA产生正链RNA
Positive-strand produced from negative-strand RNA containing coat protein subgenomic promoter of tobacco mosaic virus
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乙肝病毒核心启动子部分缺失对其活性及X蛋白转式激活作用的影响
Effects of HBV core promoter with partial deletion on its activity and on trans - acting function of X-protein
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大连地区汉族人BβFg基因启动子区-455G/A多态性分析
The Study on the Promoter Region of β - fibrinogen Gene Polymorphisms in Dalian Chinese
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噬菌体展示技术筛选诱导型NOS基因启动子DNA结合蛋白的研究
Screening of promoter DNA-binding protein of iNOS gene by phage display technique from human liver cDNA library
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白介素4基因启动子(C590T)通过PCR限制性扩增片段长度多态性(PCRRFLP)方法检测。
IL-4 C-590T polymorphisms were determined by PCR-RFLP ( restriction fragments length polymorphisms ) .
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β-肌动蛋白启动子指导下人bcl-2转基因小鼠模型的建立
Establishment of transgenic mouse model carrying bcl-2 under the direction of β - actin promoter
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HBeAg阴性慢性乙型肝炎患者出现前C和基本核启动子联合突变的意义
The significance of united mutations in precore and BCP of HBV in patients with HBeAg-negative hepatitis B
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MMP-9基因启动子单核苷酸多态性与子宫内膜异位症遗传易感性的关系
Polymorphisms in MMP-9 gene promoter and genetic predisposition of endometriosis
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iNOS启动子-969G→C多态性可导致该基因启动子功能活性增强。
The polymorphism of iNOS promoter - 969G → C results in functional activity increase of the iNOS promoter .
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血液系统肿瘤中WT1基因突变及启动子区域DNA甲基化的研究
Study on WT1 Gene Mutation and Its Promoter Region DNA Methylation Status in Hematology Neoplasms
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survivin基因启动子在多种肿瘤细胞株中的转录活性研究
Transcriptional Activity of Survivin Promoter in Tumor Cell Lines
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LPS诱导uPA启动子的分子机制的研究
The Molecular Mechanism Study of LPS Induced the uPA Promoter Elements
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端粒末端DNA形成G-四螺旋,能阻止端粒酶发挥功能,抑制端粒酶活性,另外在一些癌基因的启动子区域也可形成G-四螺旋,控制癌基因。
Telomeric DNA formats G-quadruplex , thereby inhibits telomerase activity . Also , formation of G-quadruplex in promoters of several oncogenes can inhibit expression of oncogenes .
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利用DNA改组技术改造aacC1基因启动子活性的研究
Study on DNA Shuffling Method for Changing the Promoter Activity of aac C1 Gene
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ACTE3启动子是本实验室从棉花的基因组中分离的actin基因启动子。
ACT E 3 is an actin promoter that was isolated from cotton in our lab.
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目的观察转录因子Egr(Earlygrowthresponsefactor,早期生长反应因子)是否参与调控皮质酮处理的Leydig细胞中FasL启动子的活性。
Objective To observe whether Egr ( early growth response factor ) is involved in activation of FasL promotor in CORT-treated Leydig cells .
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用COX一2启动子构建的重组载体需经合理修饰后才可用于卵巢癌的基因治疗。
With proper modification , COX-2 promoter is useful in gene therapy of ovarian cancers .
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survivin基因启动子区-31C/G多态性与散发性结直肠癌遗传易感性的关系
Association between survivin promoter - 31C / G polymorphism and genetic susceptibility to sporadic colorectal cancer
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IL-6启动子活性检测方法的建立及其在前列腺癌研究中的应用
The Establishment of the Method of IL-6 Promoter Activity Assay and Its Application in the Research of Prostate Cancer
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Connexin32启动子P2突变是周围神经功能障碍的机制
Connexin 32 promoter P 2 mutations : A mechanism of peripheral nerve dysfunction
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用不同的SD序列LT-B基因的表达水平也有所不同,用基因本身SD序列可能要比用pBV220PL启动子下游的SD序列好;
The different SD sequences can affect the expression of LT-B gene a little .
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目的鉴定人胰岛素基因启动子中的GC盒(-348 ̄-338)是否是启动子中的关键顺式作用元件。
Objective To identify whether GC-box ( - 348 to - 338 ) in human insulin gene promoter is a key cis-acting element .