兴奋性神经递质

从而说明Glu是诱发癫痫发作的主要兴奋性神经递质，而GABA有阻仰中枢神经元异常放电的作用，减缓癫痫的发作。

It is suggested that Glu is the principal excitatory neurotransmitter inducing epileptic seizures , but GABA suppresses abnormal nervous discharge of central neurons , and reduces epileptic seizures .

谷氨酸是中枢神经系统（CNS）中的主要兴奋性神经递质，有两种受体，代谢型谷氨酸受体和离子型谷氨酸受体。

Glutamate is the major excitatory neurotransmitter in the central nervous system ( CNS ), and is the agonist of two distinct categories of glutamate receptors , metabotropic glutamate receptors and ionotropic glutamate receptors .

LTP的发生与突触前兴奋性神经递质释放概率增加有关。

The induction of AC-MGB LTP maybe caused by an increase in the neurotransmitter release probability and should be presynaptic .

在该通路中，谷氨酸（glutamate，Glu）是主要的兴奋性神经递质，小白蛋白（parvalbumin，PV）是主要的钙结合蛋白，它们在口面部本体感觉信息的传递中起着重要作用。

In this pathway , glutamate ( Glu ) as the main excitatory neurotransmitter and parvalbumin ( PV ) as the main calcium-binding protein play important role in the transmission of the orofacial region proprioceptive sensory information .

谷氨酸（Glu）作为中枢神经系统的主要的兴奋性神经递质，是重要的致痫原因，既可导致癫痫发作，又可能在癫痫的继发性脑损害中起重要作用。

Glu , one of main excitatory neurotransmitters in central nervous system , is a etiological factor of epilepsy . It can not cause epilepsy but also may play a important part in the brain damage caused by epilepsy .

谷氨酸（glutamate，Glu）是细胞外最主要兴奋性神经递质，使兴奋性氨基酸维持在相对较低的水平，可确保适当的信号-噪声比率和防止谷氨酸受体过度激活而导致细胞死亡。

Extracellular concentrations of the predominant excitatory neurotransmitter , glutamate , and related excitatory amino acids are maintained at relatively low level to ensure an appropriate signal-to-noise ratio and to prevent excessive activation of glutamate receptors that can result in cell death .

中药对兴奋性神经递质谷氨酸的影响

Effect of Traditional Chinese Medicine on Excitatory Neurotransmitter

脑室微量注射兴奋性神经递质谷氨酸对消炎痛－胃溃疡的抑制效应

Suppressive Effect of Intracerebroventricular Microinjection of Excitatory Neurotransmitter Glutamate on Indomethacin-Induced Gastric Ulcer in Mice

抑制兴奋性神经递质释放，减轻其兴奋毒性。

And GS may inhibit the release of excitatory neurotransmitter , thereby reducing its excitotoxicity .

近年来研究表明，锰可干扰脑内的兴奋性神经递质谷氨酸的代谢而产生间接兴奋性神经毒作用。

In recent years studied indicated , Mn may disturb excitatory neurotransmitter Glutamate metabolism to induce the indirect excitability neurotoxicity .

谷氨酸是广泛存在于大脑的兴奋性神经递质，通过感觉传入形成意识和记忆。

Glutamine is an excitory neurotransmitter generally existing in the brain , which can form consciousness and memory through sensory afferent .

多巴胺为纹状体抑制性神经递质，而乙酰胆碱的作用则相反，即属纹状体的兴奋性神经递质。

Dopamine is Inhibitory neurotransmitters in the striatum , the role of acetylcholine on the contrary , Striatum is an excitatory neurotransmitter .

结论亚低温时对脑缺血的保护作用机制可能与减少兴奋性神经递质谷氨酸及一氧化氮的释放有关。

Conclusion The protective mechanism of mild hypothermia against encephalic ischemia may be related to decreased release of the excitatory neurotransmitter glutamic acid and nitric oxide .

谷氨酸是哺乳动物中枢神经系统重要的兴奋性神经递质，参与了学习、记忆、药物依赖成瘾及神经系统退行性疾病等多种病理生理过程。

Glutamate is an important excitatory neurotransmitter in mammalian central nervous system involved in learning , memory , drug addiction and nervous system rely on a variety of degenerative diseases .

谷氨酸是视网膜内主要的兴奋性神经递质，也是一种潜在的兴奋性毒素，过量将导致神经细胞的死亡，其毒性作用呈剂量依赖性。

Glutamate is the predominant excitatory nerve transmitter substances but a potential excitotoxin in the same time owing to causing damage even death of nerve cells when it is overdosed .

结论：谷氨酸是诱发癫病发作的主要兴奋性神经递质，而γ－氨基丁酸有阻抑中枢神经元异常放电的作用，减缓癫痫发作。

Conclusion Gin is the principal excitatory neurotransmitter induced epileptic seizures , but GABA plays a role to suppress abnormal nervous discharge of central neurons , and to reduce epileptic seizures .

胆囊对兴奋性神经递质和胃肠激素反应减弱是引起糖尿病胆囊运动迟滞的主要原因。

The decrease in the magnitude of the contractile responses to neurotransmitter and gut hormone with no change in the sensitivity to them in diabetes mellitus can led to the gallbladder hypomotility .

肢体再灌注损伤是一个复杂的病理过程，其致病因素包括氧自由基、脂质过氧化、细胞内Ca2+超载、兴奋性神经递质毒效应及炎性损害等多种病理机制。

Limb ischemia / reperfusion injury is a complicated pathological process caused by many pathogenic factors , including oxygen free radicals , lipid peroxidation , intracellular calcium overload , toxic effect of excitatory neurotransmitters , inflammatory lesion and so on .

谷氨酸是大脑神经元释放的一种兴奋性神经递质，谷氨酸的过多释放可以引起神经元的过度兴奋，造成神经元损伤或者死亡。

Glutamate is a powerful excitatory neurotransmitter which it is released by nerve cells in the brain . In many cases , cells activated by glutamate become overexcited . This overexcitation can lead to effects that can cause cell damage and / or death .

在体微透析检测豚鼠胆红素脑病模型脑组织兴奋性氨基酸神经递质

Microdialysis of Hippocampus for Measurement of the Neurotransmitter in Bilirubin Induced Encephalopathy Guinea Pigs in Vivo

目的：观察丙戊酸（valproate，VPA）对戊四氮（pentylenetetrazol，PTZ）点燃的自由活动大鼠海马胞外兴奋性氨基酸类神经递质动态释放过程的影响。

Aim : To study the dynamic release of amino acid transmitters induced by valproate in pentylenetetrazol-kindled freely moving rats ' hippocampus .

结论中风后遗症气虚血瘀动物模型的脑组织兴奋性氨基酸类神经递质（主要是Glu）含量异常升高，高于非气虚血瘀动物模型。

Conclusion The contents of the exciting aminoacid neurotransmitters ( main is Glu ) in the brain of the stroke sequela models of rats which lack Qi and have blood silted had increased , for lack of Qi and blood silt .

与传统抗癫痫药物作用于离子通道或兴奋-抑制性神经递质系统不同，其抗癫痫机制可能是通过与脑内突触囊泡蛋白SV2A结合而发挥作用。

It is approved in 2007 in China . Unlike other traditional AEDs which act on the ion channels or activate the Inhibitory Neurotransmitter system , it produces its effect by binding to synaptic vesicle protein 2A ( SV2A ), an integral membrane protein located on synaptic vesicles .

结论氨基酸类神经递质的浓度，特别是抑制性-兴奋性氨基酸类神经递质比与气质类型有一定的关系。

Conclusions Amino-acid neurotransmitters are involved in the temperament type .

目的：探讨长期给酒精对大鼠海马兴奋性氨基酸类神经递质的作用。

Objective : To study the effect on the excitatory amino acid in hippocampus of conscious rats by long-term ethanol treatment .

结论：清醒动物急性低血压影响前庭神经内侧核功能活动的过程中可能有兴奋性氨基酸-谷氨酸神经递质参与。

CONCLUSION : Glu neurotransmitter , excitatory amino acids , may contribute to the effects of acute hypotension on the activity of MVN in conscious animals .

左乙拉西坦的确切抗癫痫机制尚不明，但与传统抗癫痫药物作用于离子通道或兴奋性、抑制性神经递质系统不同。

The precise mechanisms of its antiepileptic effect is unknown and does not appear to derive from any ion passage interaction with known mechanisms involved in inhibitory and excitable neurotransmission .

它们广泛分布于神经系统，主要参与各种生理和病理作用，如膜兴奋性的产生、神经递质的释放、神经元细胞的增殖和退化，以及神经网络的信号传递等。

They are prominent in nervous system , acting in delicate and accurate ways to control or modify many physiological and pathological functions including membrane excitability , neurotransmitter release , cell proliferation or degeneration , signal transduction in neuronal network .

既往国家自然科学基金资助项目理气扶正类中药消除运动性疲劳的机理研究表明，理气扶正类中药即疏肝理气和益气健脾类中药可以起到调节兴奋性和抑制性神经递质失调的作用。

Previous Natural Science Foundation-funded projects " adjusting and nourishing Qi with Chinese medicine to eliminate fatigue " shows that soothing the liver and invigorating the spleen medicine have a better regulation of excitatory and inhibitory neurotransmitter imbalance in the Role .

因此寿尔智通过上述作用机理产生了对海马神经元既兴奋神经细胞又节制其兴奋性神经递质过度释放的作用。

Therefore , Shou ' erzhi could both stimulate the neurons cells and inhibit the excitatory neurotransmitter release excessively , through action mechanism mentioned above .