非竞争性

由于知识的非竞争性，基于RD的内生增长模型存在规模效应，即人口数量越大，从事RD的人员越多，经济增长率越快。

Because of the non-rivalry of knowledge , the R D based endogenous growth model implies the scale effect , which means the larger the population , and the more the number of R D employee , the faster the economy grows .

公共物品消费过程中所具有的非排他性和非竞争性特点，导致市场在提供公共物品时出现失灵现象，在这种情况下，政府成为公共物品的唯一提供者。

Because of public goods ' two characteristics , non-excludability and non-rivalry , the market cannot provide it efficiently , the government become the sole providers in the public goods market .

最佳pH值为7.7。结论：高浓度表面活性剂对酶表现非竞争性抑制作用；

Optimum pH is 7.7 . Conclution : Higher concentration of surfactant showed a non - competitive inhibition on the lipase activity ;

氯仿－乙醇混合液（2∶3／v∶v）对该酶的抑制属于非竞争性抑制。

The inhibition of the mixture of chloroform-enthanol ( 2 ∶ 3v / v ) on this enzyme is noncompetitive .

另一种血栓烷A2拮抗剂S145也非竞争性的抑制AA的上述反应。

Another TXA2 antagonist , S-145 also inhibited the both responses in a non-competive manner .

Dox非竞争性抑制Tet-激活的P-gpATPase活性。

Moreover , Dox inhibited Tet-activated P-gp ATPase activity in a noncompetitive manner .

实验表明：GM1对兔红细胞膜钠泵有激活作用，而GM3则为非竞争性抑制作用，Vm发生改变而Km不变。

The results indicate that GM1 activates the sodium pump , but GM3 is a non-competitive inhibitor of the sodium pump in rabbit red cells .

盐酸美金胺是盐酸金刚烷胺衍生物，它是具有中等亲和力的非竞争性的N-甲基-D-天门冬氨酸（NMDA）受体拮抗剂。

Memantine hydrochloride is an amantadine derivative . It is a moderate affinity , non-competitive N-methyl-D-aspartate ( NMDA ) antagonist .

动力学研究表明，在不同Na~+、K+浓度对，GM3对Na~+、K~+-ATP酶的抑制作用，均呈非竞争性抑制。

Kinetics studies of Na + , K + - ATPase showed that GM3 acted as a non-competitive inhibitor when the concentrations of Na + , K + and ATP changed .

有报道非竞争性NMDA受体拮抗剂能使精神分裂症患者和健康志愿者产生精神分裂样症状。

The non-competitive antagonist of NMDA / glutamate receptors has recently been shown to induce schizophrenia-like symptoms in healthy volunteers and in schizophrenic patients .

其作用机制可能与非竞争性拮抗毒覃碱样受体、组胺受体以及阻断电压依赖性钙通道（PDC）、胃肠激素的调节有关。

The mechanism of such action maybe related to the non-emulous antagonism of Muscarinic receptor , Histamine receptor , PDC and modulation of gastrointestinal hormone .

结论龙葵碱是NAT酶2-AF底物的非竞争性抑制剂。

CONCLUSION Solanine is a non-competitive inhibitor of NATs .

目前开发的P-gp抑制剂多数都是通过，直接与P-gp上药物结合位点作用，竞争性或非竞争性地抑制P-gp转运药物。

The majority of P-gp inhibitors are passed directly with P-gp drug binding sites , competitive or noncompetitive inhibit the function of P-gp .

槲皮素竞争性抑制CYP3A2右美沙芬N脱甲基反应，非竞争性抑制CYP2E1氯唑沙宗6羟化反应。

QU exhibited competitive inhibition of CYP3A2 dextromethorphan N-demethylation reaction and expressed noncompetitive inhibition of CYP2E1 chlorzoxazone-6-hydroxylation reaction .

由甲基化引起基因沉默而出现的肿瘤，可通过DNA甲基转移酶非竞争性或竞争性抑制剂抑制甲基化的发生，活化沉默的抑癌基因，从而达到治疗肿瘤的目的。

Caused by the methylation of gene silencing the tumor , available through DNA methyltransferase non-competitive or competitive inhibitors methylation occurs , activating the silence of the tumor suppressor gene , so as to achieve the aim of the treatment of tumors .

Cl－对底物CDNB有竞争性抑制作用，对GSH是非竞争性抑制作用；

The kind of inhibition by Cl - is competitive for CDNB and non competitive for GSH , respectively .

大量研究证实，非竞争性NMDA受体拮抗剂美金胺（Memantine）可以有效地减少缺氧缺血所导致的脑损伤。

It is reported that Memantine , an uncompetitive NMDA receptor antagonist , can dramatically reduce the degree of brain damage caused by hypoxic ischemia .

毛果芸香碱对ETA呈非竞争性拮抗作用，可作为区分ETA和M受体的工具药。

The antagonism of pilocarpine was fit for noncompetitive . Pilocarpine will be used as a marker of distinguishing different between ETA and M receptors . 3 .

抑制动力学分析表明，何首乌提取物对FAS的抑制和底物NADPH之间呈非竞争性关系，和丙二酰辅酶A接近竞争性关系，而与乙酰辅酶A为反竞争性关系。

The assay of inhibition kinetics showed that the inhibition to FAS by extract of TFR was non competitive against substrate NADPH , nearly competitive against malonyl CoA and un competitive against acetyl CoA .

目的观察非竞争性NMDA受体拮抗剂地艹卓西平马来酸盐（MK-801）在低剂量时对小鼠焦虑、抑郁以及学习记忆能力的影响。

ObjectiveTo investigate the effect of low dose of N-methyl-D-aspartate ( NMDA ) receptor antagonist MK-801 on the ethology of anxiety , depression , learning and memory in mice .

用硫脲标记乙肝抗体（抗HBs），基于抗原抗体高选择性识别，建立了非竞争性毛细管电泳免疫分析乙肝表面抗原的新方法。

Using capillary electrophoresis linked with conductance detection , a novel highly selective assay using antigen-antibody recognition was developed for the determination of hepatitis B surface antigen ( HBsAg ) .

目的探讨新型非竞争性5α还原酶抑制剂爱普列特（epristeride）治疗良性前列腺增生（BPH）的有效性及安全性。

Objective Study the efficacy and safety of epristeride , a new uncompetitive 5 α - reductase inhibitor , in the treatment of benign prostatic hyperplasia ( BPH ) .

结论异丙酚以非竞争性的方式抑制了DAT的转运功能，降低了多巴胺（DA）的再摄取，导致突触间隙DA浓度升高，从而增强了中枢多巴胺能神经信息的传递。

Conclusion Propofol inhibits the transport ability of DAT in a noncompetitive fashion and reduces the reuptake of dopamine , leading to elevation in DA concentration in the synaptic cleft and potentiation of dopaminergic neurotransmission in central nervous system .

动力学研究（Lineweaver-Burk作图法）发现，GLPIA1是蛋白酶A的非竞争性抑制剂。

Kinetic studies ( Lineweaver-Burk method ) showed GLPIA_1 is a kind of noncompetitive inhibitor to yeast proteinase A .

MNDA受体拮抗剂主要分为二大类，即竞争性拮抗剂和非竞争性拮抗剂，本文综述了竞争性NMDA受体拮抗剂的研究进展。

The antagonists of the NMDA ( N-methyl-D-aspartate ) receptor are divided into two classes , the competitive antagonists and the non-competitive antagonists . In this article , the competitive antagonists of the NMDA receptor are reviewed .

Glu对原代培养12天的海马神经元具有明显毒性作用，非竞争性N-甲基-D-门冬氨酸受体拮抗剂MK-801（10μM）可明显降低Glu诱导神经元死亡与凋亡。

It was obviously that Glu have toxicity to neurons at the 12th cultured day . Noncompetitive NMDA receptor antagonist , MK-801 , could reduce ratio of neuron death and apoptosis induced by Glu .

二氧化硫衍生物对去甲肾上腺素（NE）、氯化钾（KCl）和钙离子（Ca2+）引起的血管收缩呈非竞争性拮抗作用，其拮抗系数分别为0.43,2.03,2.49。

The contraction responses induced by norepinephrine ( NE ), potassium chloride ( KCl ), and Ca ~ ( 2 + ) were antagonized SO_2 derivatives in a non-competitive manner . The pD ′ _2 values were 0.43,2.03, 2.49 respectively .

将动物随机分为正常对照组、Glu-Na致痫组及D-AP-5（非竞争性NMDA受体拮抗剂）+GluNa组。

All rats were divided randomly into three groups : control group ; sodium glutamate group ; and D-AP-5 ( noncompetitive NMDA receptor antagonist ) + GluNa group .

从经典的竞争性RIA到以IRMA开始的非竞争性免疫分析和多分析物微点阵的出现，其中非竞争分析的成功是一个历史性转折。

During the course of classical competitive RIA ( radioimmunoassay ) to non-competitive assays beginning with IRMA ( immunoradiometric assay ), and further to multi-analyte micro-array , the success of non-competitive assay was a historical turning point .

Ca~（2+）累积量效曲线表明，DSPM与DSPM-Cl能使CaCl2量效反应曲线右移，最大效应降低，呈非竞争性拮抗。

DSPM and DSPM-Cl , which shifted the cumulative dose-response curvets to the right and depressed the maximal responses to CaCl_2 , acted as non-competitive antagonists .