选择素家族

细胞黏附分子选择素家族中E-选择素及其基因多态性

E-selectin and gene polymorphism in cellular adhesion molecular selectin family

选择素家族分子对于白细胞沿着血管内皮的滚动起重要作用。

The members of selectin family play an important role during the lymphocytes rolling on the vessel .

炎症反应过程是选择素家族成员与其糖基化的配体相互作用的结果。

The inflammation reaction depends on the function of the members of selectin family and their glycosylated ligand .

血流状态下白细胞的募集是一个非常快速的过程，需要特别的机制建立白细胞与内皮细胞间的联系，选择素家族代表了一类适应这一特殊目的的黏附分子。

The recruitment of leukocytes from the flowing bloodstream is a very rapid process that requires special mechanisms for the establishment of leukocyte-endothelium contacts . The selectins represent a class of cell adhesion molecules that is specialized for this purpose .

Visfatin能发挥类似于胰岛素的作用，降低血糖；并能促进脂肪细胞的合成和储积。E-选择素是粘附分子选择素家族的一员。

Visfatin similar to insulin , can play a role in reducing blood sugar . And Visfatin also can promote the synthesis and accumulations of fat cells.E-selection is a member of the adhesion molecules family .

P选择素是细胞黏附分子中选择素家族成员，介导血小板活化及炎症反应等。

P-selectin is a membrane glycoprotein belonging to the selectin family , acts as a cell-adhesion molecule in activated platelets and endothelial cells .