辅因子

乙醇被ADH代谢分解，而NAD常被认为是代谢过程中的辅因子。

Ethanol is metabolized by ADH , and NAD is used as a cofactor in its metabolism .

方法：用国产Sjamp作为激动剂，在正常混合血浆体系、纯化的肝素辅因子Ⅱ（HCⅡ）体系以及纯化的抗凝血酶Ⅲ（AT－Ⅲ）体系研究Sjamp的抗凝血酶作用机制。

Methods : The antithrombin mechanism of Sjamp was checked by assaying its effects on the thrombin activity in normal human pooled plasma , purified human heparin cofactor ⅱ ( HC ⅱ) system and antithrombin ⅲ ( AT ⅲ) system .

方法采用双基因混合注射的方法，将人MCP（膜辅因子蛋白）和CD59（膜反应性溶解抑制物）两种基因导入521枚KM小鼠的受精卵原核。

Method Double gene mouse was founded by mixed injection . Mixed human MCP and CD59 gene was injected into pronuclear of 521 mice zygote .

经过几十年研究，出现了酶法、化学法、电化学法、光化学法和基因工程法等手段实现烟酰胺类辅因子（NAD（P）H）、ATP、糖核苷酸等辅因子再生。

After two decades of research , various cofactors , such as NAD ( P ) H , ATP , sugar nucleotides can now be regenerated using enzymatic , chemical , electrochemical , photochemical or genetic engineering based methods .

不相容双质粒共表达大肠杆菌肉碱脱水酶基因caiB及其辅因子合成酶基因caiE

Coexpression of caiB and caiE with Incompatible Plasmids in E.coli

重组鼠肝素辅因子Ⅱ在大肠杆菌的表达及纯化

Recombinant murine heparin cofactor ⅱ: expresslon in E. coli and purification

对辅因子再生研究中取得的进展以及存在的问题进行讨论。

The recent advances in cofactors regeneration are reviewed in this paper .

氧化还原酶辅因子的使用偏好与化学基础

The usage bias of redox cofactors and chemical basis

雄激素受体辅因子与雄激素非依赖性前列腺癌关系的研究

The Study on the Relation of Androgen Receptor and Androgen - Independence Prostate Cancer

方法：血小板聚集机能测定和发色基质法测定肝素辅因子的抗凝血酶活性。

Methods : Platelet aggregation assay and chromogenic assay were used in this research .

烟酰胺类辅因子的保留和再生研究进展

Advances in Retention and Regeneration of Nicotinamide Cofactors

许多有价值的酶催化反应都需要辅因子的参与。

Cofactor-dependent enzymes catalyze many useful reactions .

血栓疾病患者血浆肝素辅因子Ⅱ活性和抗原水平检测及意义

Heparin cofactor ⅱ( HC ⅱ) activity and antigen assay and their significance in thrombotic diseases

高半胱氨酸的致血栓效应不依赖于血小板聚集和肝素辅因子活性

Thrombosis induced by homocysteine does not depend on platelet aggregation or heparin cofactor 's antithrombin activity

由于生物转化过程辅因子使用成本高，故需进行原位再生。

However , the high cost of cofactor requires in situ cofactor regeneration for industrial application .

刺参酸性粘多糖介导肝素辅因子Ⅱ对凝血酶活性的抑制

The antithrombin action of stichopus japonicus acid mucopolysaccharide ( Sjamp ) is mediated by heparin cofactor ⅱ

辅因子再生研究进展

Progresses on cofactor regeneration

因为辅因子价格昂贵，所以，在酶催化工业应用中，需要实现辅因子原位再生。

Due to the high cost of the cofactors , in situ cofactor regeneration is required for preparative applications .

着重介绍化学修饰酶的研究与进展，并对其发展进行了展望，主要内容包括交联技术、定点突变和化学修饰结合技术、小分子修饰、单功能聚合物化学修饰、辅因子引入。

This paper includes enzyme crosslinking , site-directed mutagenesis , small molecular compounds , homo-functionality polymerization , cofactor introduction .

吡啶核苷酸辅因子NADH/NADPH参与了该细胞还原反应，并且只有活体细胞才能催化这种反应。

This cellular reduction reaction involves the pyridine nucleotide cofactors NADH / NADPH and is only catalyzed by living cells .

这一过程是由一系列酶和辅因子催化的，这些酶和相关的辅因子统称为凝血因子。

This process catalysis by a series of enzymes and cofactors . These enzymes and cofactors all be called coagulation factor .

然而，由于加氧酶的固有性质以及对氧气和辅因子的需求，使得其大规模的应用至今还不可行。

However , large-scale applications are not yet feasible owing to the intrinsic properties of oxygenases and the requirement for oxygen and cofactors .

它们结构中可能含有非蛋白的部分（辅因子），既可以是无机离子，也可以是有机成分（辅酶）。

They may have a nonprotein part ( cofactor ), which may be an inorganic ion or an organic constituent ( coenzyme ) .

目前，酶的再设计都集中在改变酶分子的底物或辅因子的专一性及反应的立体专一性，而鲜有改变反应的化学专一性的报道。

So far , all the examples of enzyme redesign have focused on changing substrate or cofactor specificity or altering the stereochemistry of a reaction , but no body has demonstrated alteration of reaction chemistry .

方法：观察通脉降脂口服液对实验性高胆固醇血症鹌鹑动物模型血脂、血浆D-二聚体、第八因子辅因子及主动脉病变的影响。

Method : To observe the effect of this oral solution on blood lipid , plasma D D and VIIIF , and pathologic change of aorta in the duplicated model of quails with experimental hypercholesterolemia .

转录辅激活因子CBP在脂代谢中的作用

Function of Transcription Coactivator CBP in Lipid Metabolism

SRA基因是一种类固醇激素受体的转录辅激活因子，也是首次发现的可以从RNA和蛋白质两个水平上发挥作用的分子。

SRA , a steroid receptor coactivator , is the first found molecule that has the unusual property to function both at the RNA and the protein levels .

CREB结合蛋白（cAMPresponseelementbindingproteinbindingprotein，CBP）是一种重要的转录辅激活因子，具有高度保守的序列，能够与300多种转录因子相结合，被认为是哺乳动物基因转录调控中的关键位点。

CREB binding protein ( CBP ) is a crucial transcriptional coactivator , which contains highly conserved sequence and can interact with about 300 kinds of transcription factors , and is considered to be the key point of the regulation of mammalian genes transcription .

细菌碱性磷酸酶-人甾体受体辅活化因子-1的表达及应用

Expression and Application of Bacterial Alkaline Phosphatase - Steroid Receptor Coactivator-1 Fusion Protein

类固醇受体辅活化因子家族与乳腺癌

Steroid Receptor Coactivator Family and Breast Cancer