转录后调节

PIP反义核酸对乙肝病毒PRE转录后调节的影响

The function of antisense PIP RNA on HBV PRE-dependent post-transcriptional regulation

miRNA参与基因的转录后调节，对基因表达具有重要调控作用。

MiRNA plays an important role in the post-transcriptional regulation of gene expression .

HBV转录后调节基序相互作用蛋白的筛选与鉴定研究

Screening and Identification of the Interacting Proteins of HBV Post-Transcriptional Regulatory Element

HBV转录后调节序列中与干扰素α应答有关位点的初步鉴定与分析

Preliminary identification and analysis of different points related with response to interferon - α in HBV post-transcriptional regulatory element

早产儿慢性肺部疾病与IL-8产生增多的相关性：转录后调节的意义

Correlation of augmented IL-8 production to premature chronic lung disease : Implication of posttranscriptional regulation

目的研究乙肝病毒转录后调节元件（PRE）结合蛋白PIP在PRE转录后调节机制中的作用。

Objective To study the function of HBV PRE-interacting protein ( PIP ) on PRE-dependent post-transcriptional regulation .

目的筛选乙型肝炎病毒（HBV）感染者转录后调节序列中与干扰素α治疗应答有关的差异位点。

Objective To screen the differential points related with response to interferon - α in HBV post-transcriptional regulatory element ( HPRE ) .

microRNA（miRNA）是一组在进化上高度保守、非编码蛋白、参与转录后调节的小分子RNA（19-25核苷酸）。

MicroRNA ( miRNA ) is evolutionarily conserved , non-coding small RNA ( 19-25 nt ) involved in post-transcriptional gene regulation .

结论PIP反义核酸可有效地降低依赖于PRE的CAT的表达，PIP在PRE转录后调节中起着重要的作用。

Conclusion The level of CAT , whose expression was dependent on PRE function , decreased obviously by PIP antisense RNA . So PIP may play an important role in PRE posttranscriptional regulation .

对乙型肝炎病毒转录后调节序列（HPRE）在非细胞毒机制中的作用及其异质性的生物学意义进行研究，探讨IFN-γ、TNF-α和IFN-α对乙型肝炎病毒转录后调节的影响。

To explore the effect of IFN - v and TNF - a on hepatitis B virus posttranscriptional regulatory element s.

干扰素γ和肿瘤坏死因子α对乙型肝炎病毒转录后调节序列功能的影响

Effect of IFN - γ and TNF - α on hepatitis B virus posttranscriptional regulatory elements

这一作用主要通过活化蛋白激酶C（PKC）通路来实现，而CD133抗原表达可能是转录后进行调节。

This function is accomplished through activating the PKC , and the expression of CD133 is regulated possibly after transcription .

结论T3可增加细胞Fn的表达，而对TfR的表达无明显调控作用，其机制除包含转录后的调节外，可能还具有转录水平的调控作用。

Conclusion T 3 increased Fn expression of K562 cells through the possible mechanisms of either the post-transcriptional regulation or transcriptional modulation .

MicroRNAs（miRNAs）是非编码的小RNAs，在动物、植物和真菌的转录后基因调节中起重要的作用。

MicroRNAs ( miRNAs ) are small noncoding RNAs that play very important roles in posttranscriptional gene regulation in animals , plants , and fungi .

龙眼APX的活性可能是由两种方式调控：通过蛋白质-蛋白质相互作用；通过转录和转录后调节。

The activity of longan APX might be controlled by two ways : modulating through protein-protein interactions and modulating through transcription by transcriptional or post-transcriptional regulation .

各种证据表明，这些非编码元件通过复杂的网络途径，在转录和转录后调节以及染色质修饰等方面发挥着重要和多样化的作用。

A range of evidence suggests that these non-coding elements act through complex networks to fulfil important and diverse roles as transcriptional and post-transcriptional regulators and as guides of chromatin-modifying complexes .

引起外源基因失活的原因是多方面的，外源基因失活在DNA修饰水平，基因转录水平和转录后调节水平均可能发生。

There are many reasons that cause transgene inactivation , and inactivation can emerge at different gene expression stage , such as DNA modification level , transcriptional level and post-transcriptional level .

对诱导分化前后c-myc基因拷贝数的比较分析表明，c-myc基因表达下降可能主要发生在基因的转录或/和转录后调节水平。

Our data also indicated that the decrease in c-myc gene expression after induced differentiation was not due to the decrease of number of c-myc gene copy , but mainly a transcriptional regulation pf c-myc .

结论IL-5可能在转录和转录后水平均参与调节骨髓嗜酸粒细胞的功能和炎症细胞在肺和骨髓之间的转运。

Conclusion IL-5 may be involved in the regulation of eosinophils in bone marrow and cell traffic between lung and bone marrow of asthma on the level of transcription or after transcription .

这是由于强势粒受精较早，受精作用从转录启动特异基因表达，同时转录后调节也起一定的作用的结果，也是强弱势粒结实率和充实度差异的本质原因。

The reasons are the superior grains fertilized earlier , fertilization promoted specific gene expression from the beginning of transcription , meantime , regulation after transcription might play some role , These are reasons of difference of setting percentage and filling rate of superior grains with inferior grains .

目的探索T7RNA聚合酶体外转录方法制备乙型肝炎病毒（HBV）转录后调节基序（HPRE）。

Objective To synthesize highly pure HBV post-transcriptional regulatory element ( HPRE ) via transcription in vitro by T7 RNA polymerase .