表没食子儿茶素

二次柱层析制备高纯度表没食子儿茶素没食子酸酯（EGCG）的工艺研究

Study on preparation process of high purity of epigallocatechin gallate ( EGCG ) by column chromatography

目的建立测定表没食子儿茶素没食子酸酯微囊含量的方法。

Objective To establish an external standard HPLC method for the determination of epigallocatechin gallate ( EGCG ) microcapsules .

HPLC分析结果显示，茶多酚制品主要含表没食子儿茶素（EGC）、表没食子儿茶素没食子酸酯（EGCG）和表儿茶素没食子酸酯（ECG）三种儿茶素。

The analysis of HPLC demonstrated that the Tea-polyphenols production mainly contained three kinds of catechin : EGC , EGCG and ECG .

这项研究仅仅是认为表没食子儿茶素没食子酸酯（EGCG）具有用于艾滋病病毒感染辅助治疗的潜力。

The study is just that epigallocatechin gallate ( EGCG ) has for the adjuvant treatment of HIV infection potential .

绿茶的主要成分表没食子儿茶素没食子酸酯（EGCG）对血小板功能影响的研究

The Effect of ( - ) - Epigallocatechin Gallate ( EGCG ), Main Component of Green Tea , on Platelet Function

他认为，新的研究结果表明表没食子儿茶素没食子酸酯（EGCG）一般耐受性良好，对某些患者似乎有益。

The new findings suggest EGCG is generally well tolerated and appears to have some benefit for some patients , he says .

经HPLC分离与DPPH测定，确定表没食子儿茶素没食子酸酯与表儿茶素没食子酸酯为茶花中主要抗氧化活性成分，在茶花提取物的抗氧化活性中起到主要的作用。

In addition , it is found that EGCG and ECG are the major active components responsible for the antioxidant activity of tea flowers by HPLC separation and DPPH assay .

目的探讨紫外线诱导真皮成纤维细胞凋亡的发生机理以及绿茶多酚的主要成分表没食子儿茶素没食子酸酯（EGCG）对凋亡的保护作用。

Objective To explore the mechanism of ultraviolet-induced fibroblast apoptosis and the protective effects of EGCG , a major green tea catechin , on it .

用后一组溶剂系统，表没食子儿茶素（EGC）、儿茶素（±C）得到了分离，纯度达到92%。

Other major components , such as ( - ) epigallocatechin ( EGC ),(±) catechin (± C ) are isolated by the last solvent systems , each at over 92 % purity .

德国的研究者发现，表没食子儿茶素-3-没食子酸（EGCG），一种在绿茶中发现的类黄酮化合物，可以阻止丙肝病毒进入到肝细胞中。

German researchers have determined that epigallocatechin-3-gallate ( EGCG ) - a flavonoid found in green tea-inhibits the hepatitis C virus ( HCV ) from entering liver cells .

目的观察中波紫外线（UVB）辐射后成纤维细胞（FB）DNA光产物环丁烷嘧啶二聚体（CPDs）产生和清除情况及表没食子儿茶素没食子酸酯（EGCG）和黄芩甙的干预作用。

Objective To investigate the production and removal of cyclobutane pyrimidine dimers ( CPDs ) induced by UVB irradiation and intervention effect by epigallocatechingallate ( EGCG ) in human fibroblasts .

采用一种连续中压硅胶柱层析分离高纯度表没食子儿茶素没食子酸酯（EGCG）及表儿茶素没食子酸酯（ECG），原料为含量高于98%的茶多酚。

A method is described for successive purification of epigallocatechin gallate ( EGCG ) and epicatechin gallate ( ECG ) by medium-pressure silica gel column chromatography . The raw material was 98 % tea polyphenols .

本论文第四部分探讨绿茶提取物中主要成分表没食子儿茶素没食子酸酯（EGCG）的抗肿瘤生化调节作用。

In the fourth part of this paper , the antitumor biochemical modulation of epigallocatechin-3-gallate ( EGCG ), which is a main constituent in green tea extract , is reported .

他认为，如果该研究结果得到证实，且其长期用药的安全性得到大规模长期研究证实，那么有希望通过补充表没食子儿茶素没食子酸酯（EGCG）延缓或避免化疗。

If the findings are confirmed and long-term safety established in larger , longer studies , the hope is that EGCG supplements can delay or prevent chemo , he says .

目的研究绿茶多酚的主要单体成分表没食子儿茶素没食子酸酯（EGCG）的多巴胺能神经元保护作用。

Objective To observe whether the dopaminergic neuroprotective effect of ( - ) - epigallocatechin gallate ( EGCG ) is associated with its inhibition of microglial cell activation in vivo .

[目的]探讨表没食子儿茶素没食子酸酯[（-）epigallocatechin鄄3鄄gallate，EGCG]对人白血病细胞K562/A02多药耐药性的逆转作用及相关机制。

To investigate the reversal effect of ( - ) epigallocatechin-3-gallate ( EGCG ) on human leukemic K562 / A02 cell line and its possible mechanisms .

目的：研究表没食子儿茶素没食子酸酯（EGCG）增强阿糖胞苷（AraC）对人白血病HL60细胞的抗肿瘤活性。

OBJECTIVE To study the potentiation of antitumor effect induced by cytosine arabinoside ( AraC ) with ( - ) epigallocatechin 3 gallate ( EGCG ) .

Shanafelt博士认为，多种类型肿瘤实验室研究已表明表没食子儿茶素没食子酸酯（EGCG）切断肿瘤组织营养丰富的血供，直接杀死肿瘤细胞。

Laboratory studies in a variety of tumor types have shown that EGCG cuts off the nutrient-rich blood supply to tumors and directly kills off cancer cells , Shanafelt says .

聚酰胺色谱法分离制备高纯度表没食子儿茶素没食子酸酯

Preparation of High Purity Epigallocatechin Gallate by Polyamide Packed Chromatographic Column Separation

绿茶提取物及表没食子儿茶素没食子酸酯对免疫细胞的作用研究

Study on the Effects of Green Tea Extract and EGCG on Immune Cells

茶多酚表没食子儿茶素-3-没食子酸酯对红细胞膜的促氧化作用

Pro-oxidative effect of epigallocatechin 3-gallate on human erythrocyte membranes

叶酸介导表没食子儿茶素没食子酸白蛋白纳米粒的制备及其体外靶向性与活性评价

Preparation , activity and targeting ability evaluation in vitro on folate mediated epigallocatechin-3-gallate albumin nanoparticles

利用寡聚环糊精配基键合介质分离表没食子儿茶素没食子酸酯的新方法

New Chromatographic Method for Separation of Epigallocatechin Gallate with Oligo - β - cyclodextrin Coupled Media

表没食子儿茶素没食子酸酯单用及联合环孢菌素A或维拉帕米逆转白血病细胞多药耐药的实验研究

Reversal of Multidrug Resistance on a Human Leukemic Cell Line by ( - ) Epigallocatechin-3-Gallate Alone or in Combination with Cyclosporin a or Verapamil

该介质同样还能够在甲醇-乙酸乙酯-水-醋酸（30∶30∶30∶10）的条件下分离茶多酚中的表没食子儿茶素。

Oligo - β - cyclodextrin-Sepharose HP media could also be used for the separation of epigallocatechin with the mobile phase of methanol-ethyl acetate-distilled-acetic acid ( 30 ∶ 30 ∶ 30 ∶ 10 ) .

在相同的氧化体系中，表儿茶素没食子酸酯（ECG）的表现不同于表没食子儿茶素没食子酸酯，表明其在该试验所选定的化学氧化条件下为相对稳定。

The behavior of ECG is different from that of EGCG under the oxidation system which indicates that ECG is relatively stable to the selected chemical oxidation conditions in this work .