血小板减少症

人血小板生成素cDNA转染及表达产物对实验性血小板减少症的治疗作用

Transfection and expression of human thrombopoietin cDNA for treatment of thrombocytopenia in mice

目的探讨脾脏射频消融术治疗顽固性免疫性血小板减少症（ITP）的安全性和有效性。

Objective To assess the safety and efficacy of radiofrequency ablation of the spleen for intractable immune thrombocytopenia ( ITP ) .

重组人白细胞介素-11治疗化疗引起的血小板减少症的II期临床研究

Phase ⅱ study of recombinant human interleukin-11 treatment for chemotherapy-induced thrombocytopenia

IL-6可治疗因化疗、放疗引起的血小板减少症。

IL-6 is a candidate drug that may prevent the thrombocytopenia caused by chemotherapy and irradiation therapy .

目的：分析消化道溃疡大出血手术治疗后引发血小板减少症（TCP）的原因及临床意义。

Objective : To study the causes and clinical relevance of thrombocytopenia ( TCP ) after operation for lethal peptic ulcer hemorrhage .

血小板减少症患者IL-11调控机制的研究

Study on Mechanism of Regulation of IL-11 to Platelet in Patients with Thrombocytopenia

血小板减少症患者TPO及其受体c-mpl调控机制的研究

A Study on Mechanism of Regulation of TPO and c-mpl in Patients with Thrombocytopenia

表明：不同病因的血小板减少症血浆TPO水平不同，外周血血小板数是血小板减少症患儿血浆TPO水平重要的反馈调节因素之一。

The peripheral blood PLT was one of important feedback regulating factors for serum TPO levels in the children with thrombocytopenia .

结果：PT的病因主要包括妊娠相关性血小板减少症（PAT）、免疫性血小板减少性紫癜（ITP）及妊高征/先兆子痫/HELLP综合征。

Results : Thrombocytopenia was mainly caused by pregnancy-associated thrombocytopenia ( PAT ), autoimmune thrombocytopenia ( ITP ) and pregnancy induced hypertension / preeclampsia / HELLP syndrome .

采用ELISA法对25例ITP患者、32例其他血小板减少症以及15例正常人血清TPO浓度进行测定。

Serum levels of TPO are determined in 25 cases of ITP , 32 cases of other thrombocytopenic diseases and 15 normal cases by means of ELISA method .

目的：免疫性血小板减少症（immunethrombocytopenia，ITP）是一种涉及体液免疫和细胞免疫功能异常的自身免疫性疾病，发病机制尚不明确。

Objective : Immune thrombocytopenia ( ITP ) belongs to an autoimmune disease and is involved in the humoral and cellular immune dysfunction . The pathogenesis of ITP are not obvious .

研究背景与目的：免疫性血小板减少症（ITP）是一种免疫介导的血小板减少综合征，是儿童最为常见的出血性疾病。

Background and Objective : immune thrombocytopenia ( ITP ) is an immune-mediated thrombocytopenia syndrome . It is the most common hemorrhagic disease during the Children .

目的：探讨血小板减少症患者血清血小板生成素（thrombopoietin，TPO）水平与外周血小板计数（plateletcounts，PLT）、骨髓巨核细胞计数的关系及临床意义。

Objective : To investigate the relationships and clinical significance among level of serum Thrombopoietin ( TPO ) 、 peripheral blood platelet counts and megakaryocyte counts in patients with thrombocytopenia .

LMWH使用方便，不增加纤溶活性，血小板减少症等副作用少，可考虑应用于DIC的全程治疗。

LMWH is easy to use and has less side effects such as thrombocytopenia , so it can be used in the whole clinical course of DIC treatment .

目的观察国产基因重组人白细胞介素-11（rhIL-11）对化疗致重度血小板减少症（TBP）的临床疗效。

Objective To observe clinical efficacy of domestic-made recombinant human interleukin-11 ( rhIL-11 ) in treatment of severe thrombopenia ( TBP ) induced by chemotherapy .

将IPMs输入血小板减少症兔出血动物模型体内，观察IPMs止血效果及对凝血系统的影响。

Hemostatic function and effect of IPMs on pathological thrombogenicity were observed after IPMs were transfused into thrombocytopenia rabbit models .

PAIg介导的自身免疫机制在病毒性肝炎血小板减少症中可能起重要作用。

Autoimmune mechanism mediated by PAIg may play an important role in thrombocytopenia associated with viral hepatitis .

结果表明全身性红斑狼疮、类风湿关节炎、血小板减少症和反复自然流产患者ACA均有较高的检出率（25.0%～33.8%）。

The results indicated that SLE 、 RA 、 thrombocytopenia and recurrent spontaneous abortion ( RSA ) groups had a higher positive rate of anticardiolipin antibodies ( 25.0 % ~ 33.8 % ) .

自从1997年10月，美国FDA批准rhIL-11（重组人IL-11，商品名oprelvekin）应用于预防非髓性恶性疾病患者化疗后并发的严重血小板减少症以来，针对其临床应用的研究逐渐增多。

Since October , 1997 , the Food and Drug Administration approved rhIL-11 for the prevention of severe thrombocytopenia following chemotherapy . More and more research aimed at IL-11 was developed .

资料病例选择为2002年2月到2009年8月期间新疆医科大学第一附属医院住院患者诊断为ITP或单纯血小板减少症的112例患者。

Material : Cases selected for the period from February 2002 to August 2009 the first affiliated hospital of Xinjiang Medical University in patients with diagnosis of 112 cases of thrombocytopenia in patients with ITP or simple .

目的探讨多种疾病患者因免疫紊乱导致血小板减少症时血小板相关抗体（PAIgG）的变化与血小板数的关系。

Objective To investigate the plasma level of platelet associated IgG ( PAIgG ) and its relation with platelet count in various kinds of disease with immune abnormal .

妊娠合并血小板减少症与心、肝、肾脏器损伤

Pregnancy with thrombocythemia and injury of heart and liver and nephridium

目的探讨妊娠合并血小板减少症的临床治疗。

To investigate the clinical therapy of pregnancy with thrombocytopenia .

妊娠相关性血小板减少症52例临床观察

Clinical features of 52 cases with pregnancy associated thrombocytopenia

接受心导管术的患者中肝素诱导血小板减少症的发生率

Prevalence of heparin-induced thrombocytopenia in patients undergoing cardiac catheterization

流式细胞术在免疫性血小板减少症诊断中的应用

Application of flow cytometry to diagnosis of immune thrombocytopenia

重组人白细胞介素11对卡铂所致猴血小板减少症的治疗作用

Therapeutic Effects of rhIL-11 on Carboplatin-Induced Thrombocytopenia in Monkeys

头孢哌酮/舒巴坦引起血小板减少症的循证分析

Evidence-Based Analysis of Thrombocytopenia Caused by Cefoperazone / Sulbactam

这些结果可能为化疗引发的血小板减少症的药物治疗增加新的选择。

These results may increase new choice in the treatment of chemotherapy-induced thrombocytopenia .

院内获得性血小板减少症对因急性心肌梗死行直接血管成形术的患者的影响

Impact of in-hospital acquired thrombocytopenia in patients undergoing primary angioplasty for acute myocardial infarction