蛋白磷酸酶

  • 网络Protein phosphatase
蛋白磷酸酶蛋白磷酸酶
  1. 根据现有的研究表明,蛋白磷酸酶参与了ABA、病原侵染、胁迫及发育信号转导途径,但是蛋白磷酸酶在花粉管极性生长中的作用机理还不清楚。

    A great number of reports have demonstrated that protein phosphatases ( PPases ) are involved in transduction pathway for ABA , pathogen infection , stresses and developmental signals .

  2. 植物蛋白磷酸酶及其在植物抗逆中的作用

    Protein Phosphatases and Their Functions in Plant Response to Environmental Stress

  3. 蛋白磷酸酶2A的结构、功能和活性调节

    Protein Phosphatase 2A : Its Structure , Function and Activity Regulation

  4. 高等植物中蛋白磷酸酶2C的结构与功能

    The Structure and Function of Protein Phosphatase 2Cs in Higher Plants

  5. 细胞内游离Ca2+升高,激活一些蛋白磷酸酶,使底物蛋白磷酸化,将外界信号级联放大,进入核内,影响DNA复制,导致细胞恶变及肿瘤细胞的增殖分化。

    The increasing of intracellular free Ca2 + active some protein phosphatase , thereby , affected cell DNA replication , leading to cell malignant transformation and tumor cell proliferation and differentiation .

  6. 蛋白磷酸酶2A在正常人子宫内膜上皮细胞的表达及其与细胞周期蛋白G1的关系

    Expression of protein phosphatase 2A in normal human endometrial epithelial cells and relation with cyclin G1

  7. JAK是一类蛋白磷酸酶,其作用底物为STAT蛋白。

    JAK is a protein phosphatase , the substrate is STAT protein .

  8. 采用免疫组织化学染色观察了纹状体边缘区蛋白磷酸酶1、磷酸化的cAMP反应元件结合蛋白表达的改变。

    The changes of the expressions of protein phosphatase 1 and phosphorylated cAMP responsive element binding protein in the marginal division of striatum were observed with immunohistochemical staining .

  9. 目的克隆杜氏利什曼原虫(Leishmaniadonovani,Ld)1S株蛋白磷酸酶2C(PP2C)的编码基因,为应用这种编码T细胞抗原的基因进行基因疫苗研究奠定基础。

    Aim To clone protein phosphatase 2C ( PP2C ) gene from Leishmania donovani 1S parasite .

  10. 结果经过克隆、测序、同源性比较,差异显示片段Se-8的碱基序列与蛋白磷酸酶2A(Proteinphosphatase2A,PP2A)的同源性为99%。

    Results The identities between the sequence of Se-8 and protein phosphatase 2A ( PP2A ) was 99 % .

  11. 含Shp-2的酪氨酸蛋白磷酸酶在神经肌肉接头形成中的作用

    The role of protein tyrosine phosphatases involved in Shp-2 in the formation of the neuromuscular junction

  12. PTEN的蛋白磷酸酶活性具有抑制细胞侵袭的作用;PTEN的脂质磷酸酶活性具有抑制细胞周期进展和诱导细胞凋亡的作用。

    PTEN may function to regulate cell migration / adhesion through its protein phosphatase activity and to regulate cellular growth and induce apoptosis through its lipid phosphatase activity .

  13. 目的研究Shp-2酪氨酸蛋白磷酸酶对白血病细胞恶性增殖的影响。

    Objective To investigate the effects of Shp-2 tyrosine phosphatase activity on unlimited proliferation of leukemia cells .

  14. [结论]荧光蛋白磷酸酶抑制法具有一定的实用价值,适用于对大批量、低剂量MC水样进行监测。

    [ Conclusions ] Fluorescent protein phosphatase inhibition assay is a rapid , sensitive detection method , which is good for screening and monitoring a large of water samples containing low concentration of microcystins .

  15. 目的探讨酪氨酸蛋白磷酸酶Shp-2和白血病抑制因子(LIF)影响HL-60细胞增殖与分化过程中的相互关系。

    Objective To probe into the relationship of tyrosine phosphatase Shp-2 and leukemia inhibitory factor ( LIF ) in influencing proliferation & differentiation of HL-60 cells .

  16. 同时变构霉素还是一种蛋白磷酸酶抑制剂,对蛋白磷酸酶1和蛋白磷酸酶2A都有很好的抑制活性。

    Moreover , tautomycin is a kind of protein phosphatase inhibitors , displaying strong inhibition against both protein phosphatase-1 and protein phosphatase-2A , So tautomycin has great potential in practical use .

  17. 采用β-还原型尼克酰胺腺嘌呤二核苷酸磷酸-黄递酶(β-NADPH-d)组织化学技术研究不同剂量蛋白磷酸酶抑制剂岗田酸(OA)对嗜铬细胞瘤细胞株(PC12)一氧化氮合成酶(NOS)活性的影响。

    Rat pheochromocytoma cells were cultured with different dose of okadaic acid ( OA ), and the activity of nitric oxide synthase ( NOS ) was detected by β NADPH diaphorase histochemistry .

  18. PP2A是主要的丝/苏氨酸蛋白磷酸酶之一。

    Protein Phosphatase 2A is one of the major serine / threonine phosphatases .

  19. 蛋白磷酸酶PP1和(或)PP2A参与调节青杆(Piceawilsonii)花粉萌发及花粉管生长

    Protein Phosphatase 1 and / or 2A is Involved in the Regulation of Pollen Germination and Tube Growth in Picea Wilsonii

  20. PTEN通过PIP3途径、FAK途径、MAPK途径等发挥其脂质磷酸酶和蛋白磷酸酶活性,诱导细胞凋亡、抑制细胞生长、调节细胞迁移与黏附;

    PTEN brings into its lipid and protein phosphatase activity through PIP_3 , FAK , MAPK pathway . PTEN also induces apoptosis , inhibites cell growth , regulates cell migration and adhesiveness .

  21. 用DEAE-Sephacel层析法部分纯化了大鼠心肌肌浆网phospholamhan(PLB)蛋白磷酸酶(PPase),并证明其是PPase-1。

    In the present study , rat cardiac sarcoplasmic reticulum ( SR ) phospholamban ( PLB ) phosphatase was partially purified by chromatography on DEAE-Sephacel .

  22. 本研究首次从中分离到小麦蛋白磷酸酶2A(PP2A)两个亚基的表达序列,进一步克隆并定位了相关的基因,深入研究其表达特性及与植物干旱响应的关系。

    Based on the EST sequences , we cloned the catalytic subunit genes and structural subunit genes of wheat protein phosphatase 2A ( PP2A ) and characterized their functions in drought stress response .

  23. 酪氨酸特异性蛋白磷酸酶(YOP)对该激酶的活性有显著的钝化作用。

    The tyrosine-specific protein phosphatase ( Yersinia enterocolitica protein , YOP ) could significantly inactivate the phosphorylation activity of protein kinase .

  24. 钙调神经磷酸酶(CaN)是丝氨酸/苏氨酸蛋白磷酸酶家族成员,分类上属于PP2B家族,是唯一受Ca2+/钙调素调节的磷蛋白磷酸酶。

    Calcineurin ( CaN ) is a serine / threonine protein phosphatase and known as the only phosphatase that regulated by Ca2 + and calmodulin .

  25. 方法用Fluo3AM荧光法和发色底物法分别测定PC12细胞在激活和脱敏状态胞内钙离子浓度和钙离子钙调蛋白依赖的蛋白磷酸酶(PP2B)活性。

    Methods The intracellular calcium concentration and the calcium-calmodulin dependent protein phosphatase calcineurin ( CaN , PP2B ) activity were determined by Fluo-3-AM fluorescence method and luminescence substrate method in the process of cell activation and desensitization .

  26. Ⅰ型蛋白磷酸酶(PP1),通过去磷酸化蛋白调节机体代谢、细胞分化以及信号转导等。它由催化亚基和调节亚基组成,后者决定磷酸酶的底物特异性,活性以及亚细胞定位。

    PP1 is composed of catalytic subunits and regulatory subunits , which modulates metabolism , cell differentiation and signal transduction by dephosphorylation . The regulatory subunits determine the substrate specificity , activity and subcellular localization of PP1 .

  27. 目的研究1型蛋白磷酸酶骨骼肌特异的糖原靶向调节亚单位基因(PPP1R3)Asp905Tyr多态性与安徽汉族人2型糖尿病(T2DM)相关性。

    Objective To study the association of muscle-specific glycogen-targeting regulatory subunit of the glucogen-bound protein phosphatase 1 ( PPP1R3 ) gene codon 905 Asp / Tyr polymorphism with type 2 diabetes in Chinese Han population in Hefei of Anhui province .

  28. PP2C蛋白磷酸酶(PP2C-typeproteinphosphatases,PP2C)是一类以丝氨酸/苏氨酸残基蛋白磷酸酶,在细胞内以单体形式存在,酶催化活性依赖于Mg2+或Mn2+。

    Two kinds of protein phosphatase ( PP2C-type protein phosphatases , PP2C ) are a kind of protein phosphatase with serine / threonine residues , its existence was monomer forms in cells , and enzymatic catalyses activity depended on Mg2 + or Mn2 + .

  29. 人再生肝脏蛋白磷酸酶-3基因的克隆与测序

    Gene of Human Phosphatase of Regenerating Liver-3 : Cloning and Sequencing

  30. 利用蛋白磷酸酶活力抑制法检测牡蛎体内的腹泻性贝毒

    Protein Phosphatase Inhibition Assay for Detection of Diarrhetic Shellfish Poison in Oyster