药物戒断

第二天，他的药物戒断综合征发展到高峰。

The severity of his drug withdrawal syndrome peaked the next day .

药物戒断引起的神经系统适应性变化主要包括突触传递的改变、神经元基因转录和蛋白表达的改变以及形态的改变（后两者决定神经元兴奋性的高低）。

Neuroadaptations induced by drug withdrawal includes alterations in the efficiency of synaptic transmission , gene transcription and protein expression and neuronal morphology ( the latter two decided the firing property ) .

神安交泰颗粒治疗失眠症苯二氮（艹卓）类药物戒断综合征的多中心临床观察

The Treatment of Shen-An-Jiao-Tai Grains on Insomnia with Benzodiazepines Drugs Withdrawal Syndrome by Multicenter Clinical Trial

目的验证曲唑酮对苯二氮类药物戒断症状的疗效及安全性。

Objective To determine the efficacy and safety of trazodone in the treatment of benzodiazepine withdrawal symptoms .

这一结果从蛋白表达的角度证明蓝斑核在阿片类药物戒断中的作用机理。

The results indicated an obvious correlation between morphine withdrawal and Fos protein expression of locus coeruleus in rats brain .

目的：复吸是指成瘾药物戒断后的恢复用药行为，药物成瘾中的一个重要特点。

Objective : Relapse refers to a behavior of taking addictive drug again after abstinence . It is an important character in drug addiction .

本研究发现的吗啡戒断时伏核的这些变化可能是觅药行为复燃的重要神经底物和药物戒断时自然奖赏因素效力下降的原因之一。

The neuroadaptations observed during morphine withdrawal in this study could be important neuronal substrates mediating reinstatement of drug seeking behavior , which could also be one of the causes underlying the reduction of rewarding effect of natural rewards during drug withdrawal .

药物依赖戒断后心理渴求的神经机制及干预措施

Neurobiological mechanisms and interventions in drug craving after withdrawal

阿片类药物依赖戒断后渴求行为和焦虑情绪的神经生物学机制研究Ⅰ：理论框架

The Neurobiological Study for Anxiety and Craving Behavior of the Withdrawal in Opioid Dependence ⅰ: Theoretical Framework

反复暴露于阿片类药物后戒断时，伏核的神经适应性变化被认为是复吸的主要神经底物之一。

Neuroadaptations in nucleus accumbens during withdrawal from repeated opioid treatment is considered to be one of the main neurobiological substrates underlying relapse .

神农栓剂是根据传统中医药基本理论组方，精选，并经临床前药理学研究结果：对阿片类药物成瘾戒断有优良作用的戒毒制剂。

The prescription of Shennong Jie Du Suppository is based on the basic theories of traditional Chinese medicine , and it has been proved by pharmacology research before clinical use that it has good effect on withdrawl syndroms of opiods addicts .

NO-cGMP信号转导系统的上调参与阿片类药物耐受和戒断的生化机制

Up-regulation of NO-cGMP signal transduction system is involved in the biological mechanisms of opiate tolerance and withdrawal

阿片类药物依赖及戒断症状的细胞分子机制和治疗

The Therapy and Cellular-molecular Mechanisms of Opioid Drug Dependence and Withdrawal

前言对阿片类药物依赖的戒断机理及治疗的研究一直是医学界关注的热点。

Forwardthe research of medical dependence therapy and abstain mechanism caused by opium has been a hotspot in medical science .

由于神经可塑性涉及到学习记忆、药物成瘾与戒断、精神性疾病等多领域的研究，因此点燃模型的应用正在向这些方向发展。

As the plasticity of the nerves are related to memory , addiction and withdrawal of drugs , psychological diseases etc , the kindling models are being used in these fields .

阿片类药物依赖稽延性戒断症状中医证候学及其计量诊断研究

Study on CM Syndrome and Its Diagnostic Evaluation for Protracted Abstinence Symptom of Opium - Addicts

稽延性戒断综合征证候特点及成瘾记忆机制初探阿片类药物依赖稽延性戒断症状中医证候学及其计量诊断研究

Study on Syndromes of Traditional Chinese Medicine in Protracted Abstinence Symptom of Opium-addicts and the Mechanisms about Addiction Memory

针刺治疗阿片类药物依赖稽延性戒断症状气血两虚型临床观察阿片依赖的循证药物治疗：从研究到应用

Acupuncture Clinical Research about Protracted Withdrawal Syndrome of Opium-addicts of Asthenia of qi and Blood EVIDENCE-BASED OPIOID PHARMACOTHERAPIES : FROM RESEARCH TO IMPLEMENTATION IN THE REAL WORLD

肝郁证原发性失眠症患者情绪状态、行为特征、体质类型特点初探针刺治疗阿片类药物依赖稽延性戒断症状气血两虚型临床观察

Study on Mood , Personality Traits and Habitus in Primary Insomnia ; Acupuncture Clinical Research about Protracted Withdrawal Syndrome of Opium-addicts of Asthenia of qi and Blood

目前临床主要采用的三种戒毒治疗方法，包括自然戒断法、药物脱毒治疗及非药物戒断法。

Three main programs have been made such as cold turkey , drug detoxification and non-drug treatment .

伏核是脑奖赏中枢的重要组成部分，参与成瘾药物的强化、耐受、成瘾过程及药物戒断综合征的表达。

Nucleus accumbens , an important component of brain-reward regions , is involved in the reinforcement , tolerance , addiction and expression of withdrawal syndrome of drug addiction .

目的：观察纳洛酮等药物在点燃模型中的作用，探讨成瘾性药物的戒断症状与点燃模型的内在联系。

Objective : To observe the effects of naloxone and other agents on amygdala kindling model in rats , and investigate the underlying relationship between the mechanism of withdrawal syndrome of addictive substances and kindling model .