自身免疫疾病

一位女士在患了引发手部剧痛的自身免疫疾病以后，被鼓励尝试编织，她在工艺纱理事会的网站上汇报说，她的手现在不那么僵硬和疼痛了。

A woman encouraged to try knitting and crocheting after developing an autoimmune disease that caused a lot of hand pain reported on the Craft Yarn Council site that her hands are now less stiff and painful .

对其中病毒性肺炎16例、GoodPasture综合征2例、自身免疫疾病2例、SARS1例，共21例进行肺部病变的病理组织学的比较观察。

Among them , 16 cases of viral pneumonia , 2 cases of Good Pasture syndrome , 2 cases of autoimmune disease and 1 case SARS were observed comparatively with the method of histopathology .

B淋巴细胞在自身免疫疾病发病中扮演着重要角色。

B lymphocytes have been shown to play fundamental pathogenic roles in autoimmune disorders .

颗粒酶B与自身免疫疾病及抗病毒感染密切相关，在恶性肿瘤细胞杀伤方面的应用价值正日益受到关注。

Granzyme B is closely related to autoimmune diseases and anti-virus infection process . It is attracting increasing attention for its application in cancer treatment .

细胞凋亡从两个方面参与自身免疫疾病的发病过程：①细胞毒性T淋巴细胞通过Fas介导的凋亡途径来杀伤靶细胞；

Apoptosis is involved in autoimmune disease in two aspects : ? cytotoxic T lymphocytes attack the target cell through apoptosis pathway signed by Fas protein .

类风湿关节炎（Rheumatoidarthritis，RA）是一种原因不明的自身免疫疾病，致残率高，严重影响病人的生活质量和预期生命。

Rheumatoid Arthritis ( RA ) is an unclear auto-immunity disease , which can severely influence the life quality and expectation of patients with high frequency of disability .

其中急、慢性疾病组除外了自身免疫疾病患者如SLE等。

Among them , patients suffered from autoimmune diseases such as SLE and gastric cancer were excluded from both of acute diseases group and chronic diseases group .

目的：利用重组抗原检测自身免疫疾病患者血清中抗SSB自身抗体并探讨其临床意义。

Objective : To detect the level of anti-SSB autoantibody in patients with autoimmune diseases using recombinant antigen to evaluate its significance .

病人患有桥本甲状腺炎，也可能患有其它自身免疫疾病，如Graves病、系统性红斑狼疮、类风湿性关节炎，恶性贫血症，以及口眼干燥综合症。

Patients with Hashimoto 's thyroiditis may also have other autoimmune conditions including Grave 's disease , SLE , rheumatoid arthritis , pernicious anemia , and Sjogren 's syndrome .

多因素非条件Logistic回归分析表明，保守治疗方式、入住ICU、罹患感染、肿瘤、脑部肿瘤、自身免疫疾病、联合用药是不合理用药的相关因素。

Multivariate unconditional logistic regression analysis showed that the conservative treatment , check the ICU , risk of infectious , cancer , autoimmune diseases , and the combination are related with irrational drug use . 3 .

因此，对BLyS及其受体的研究有助于阐明SLE等自身免疫疾病，BLyS、其可溶性受体和单克隆抗体有望开发为治疗自身免疫综合症的新型药物。

Therefore , BlyS , its receptor or related antagonists may find medical utility in the treatment of B cell disorders associated with autoimmunity , neoplasia , or immunodeficiency syndromes .

CpG序列又名免疫刺激DNA序列（ISS），可激活多种免疫效应细胞，且无免疫原性，不会引起自身免疫疾病，具有很高的实用价值，在疾病的防治研究中有着广阔的应用前景。

CPG motifs , also named Immuno stimulatory sequence , can stimulate a large variety of effective cells , have no immunogens , result in no immune diseases , possess significant practical values and great prospective in treatment and prevention of disease .

但是，最近愈来愈多的证据显示IFI-200家族成员在人类肿瘤及自身免疫疾病中起作用。

But recently , more and more evidences showed IFI-200 family members play roles in human cancers and autoimmune diseases .

近年来，CD4+CD25+Treg细胞在免疫抑制中的作用受到重视，成为研究的热点，认为CD4+CD25+Treg细胞可能参与了自身免疫疾病的发生，在AA和MDS的发病中起到一定的作用。

In recent years , the role of CD4 + CD25 + Treg in regulating immunosuppression is importance as a hot research that CD4 + CD25 + T cells may be involved in the regulation of autoimmune diseases , play a certain role in the pathogenesis of AA and MDS .

同时Pre-DC2还广泛参与病毒性疾病，自身免疫疾病，肿瘤等，本文就此作一综述。

Thus , Pre-DC2 involved in viral infectious diseases , autoimmune diseases , and tumor . Here , we review the functions of Pre-DC2 and the relations of Pre-DC2 with human diseases .

结论：BXSB小鼠粒-巨噬细胞系造血异常及外周血单核细胞增多参与了自身免疫疾病的发病过程。血常规示6例嗜酸性粒细胞升高，2例出现异形淋巴细胞，3例单核细胞增多；

Conclusion The autoimmune disease of male BXSB mice may be caused by monocytosis which comes from the abnormal CFU-GM in the bone marrow . Blood routine test showed eosinophilia in 6 cases , atypical lymphocytes in 2 cases and monocytosis in 3 cases .

敬畏的心态能有助于减少与自身免疫疾病有关的炎症因子。

Experiencing awe reduces inflammatory markers associated with autoimmune disease 。

它的多器官受累可能与自身免疫疾病的发病机制相似。

The pathogenesis of this multicentric disorder may be associated with autoimmune disease .

维生素D结合蛋白是一种免疫调节因子，其缺乏导致自身免疫疾病的发生。

Vitamin D-binding protein is an immune-regulating factor .

在小型近亲婚配的罗马尼亚社区自身免疫疾病及维生素D受体Apa-Ⅰ的多态性与白癜风相关

Autoimmune diseases and vitamin D receptor Apa-I polymorphism are associated with vitiligo in a small inbred Romanian community

间充质干细胞的免疫调节功能及间充质干细胞在治疗自身免疫疾病中的应用

Immunoregulatory Function of Mesenchymal Stem Cells and Application of Mesenchymal Stem Cells in Therapy of Autoimmune Disease & Review

风湿性关节炎是一种自身免疫疾病，可以发生在年轻人身上，导致疼痛，僵硬以及肿胀。

Rheumatoid arthritis is an autoimmune disease that can strike young people , causing pain , stiffness and swelling .

目前，器官移植术后和自身免疫疾病死亡病人中，有相当一部分是由于免疫抑制剂使用过度继发严重感染造成。

At present , deaths of most posttransplantation patients are caused by severe infection due to the overuse of immunosuppressants .

一些脑部特定的自身免疫疾病恰恰就是免疫系统紊乱的绝佳的例子。

Certain autoimmune diseases of the brain represent examples of disorders where one of these constituents plays a major role .

最新发现：表观遗传学的不断增长的知识可能给予了我们对自身免疫疾病发病机制的新的见解。

RECENT FINDINGS : The growing knowledge of epigenetics might give us new insights into the pathogenesis of autoimmune diseases .

对于自身免疫疾病患者，新免疫系统可能不再攻击自身机体。

In a person with autoimmune disease , that new immune system would likely no longer attack tissues of the body .

另一常见类型为类风湿关节炎，是一类慢性全身性自身免疫疾病，以滑膜关节炎和关节外病变为主要临床表现。

The other common type is rheumatoid arthritis ( RA ), resulting from the autoimmune disorder that causes the chronic inflammation of joints .

硬皮病，一种自身免疫疾病，多发于中年妇女，可以影响到躯体内外的多个部位。

Scleroderma , an autoimmune disease , tends to afflict middle-age women and can affect many parts of the body , inside and out .

自身免疫疾病患者，可在许多不同的器官发生脉管炎，且容易与风湿病的症状和体征相混淆。

Vasculitis with autoimmune disease can occur in many different organs and can lead to the often confusing signs and symptoms of patients with rheumatic diseases .

拥有扰乱人体免疫系统的能力&病毒作为可能的自身免疫疾病始动因子通常是免疫学家们感兴趣的研究对象。

Viruses have always attracted the interest of immunologists as possible triggers of autoimmune diseases due to their ability to interfere with the host 's immune system .