脑苷脂

脑苷脂B的结构鉴定

Chemical Structure of Cerebroside B

其中，脑苷脂的检出限为0.01μg，加标平均回收率为94.28%，RSD为5.67%，方法稳定性良好。

Among them , the detection limit of cerebroside is 0.01 μ g , average recovery rate was 94.28 % , relative standard deviation is 5.67 % , and the method has a good stability .

糖脂制剂主要成分半乳糖脑苷脂的~1HNMR定量分析

Quantitative Analysis of Galactocerebroside in Glycolipids Preparation by ~ 1H NMR

神经节苷脂GM2、GM3、GD3及脑苷脂对猪肾Na+、K+-ATP酶活性的影晌

Effects of ganglioside gm_2 , gm_3 , gd_3 on the porcine renal na + , k + - atpase activity

抗肿瘤作用：主要采用MTT法，分别考察了不同浓度、不同作用时间下海参脑苷脂及长链碱对Caco-2，S180和HL-7702三种细胞系的增殖抑制作用情况。

Anti-tumor effects : all total cerebrosides of three sea cucumbers have anti-proliferation activities on Caco-2 colon cancer cells in different concentrations , different time by MTT method .

首次应用高速逆流色谱（HSCCC）技术成功优化了海参脑苷脂的分离过程。

The first application of high-speed countercurrent chromatography ( HSCCC ) technique successfully optimized the separation process of sea cucumber cerebrosides .

先采用气相色谱质谱联用（GC-MS）法，分析比较了三种海参脑苷脂系列物的脂肪酸、长链碱和糖基组成差异。

The cerebroside series separated from the three sea cucumbers respectively are firstly analyzed by gaschromatographic mass spectrometry ( GC-MS ) to acquire the differences among the compositions of their long-chain bases ( LCBs ), fatty acids ( FAs ) and glycosides .

脑苷脂的制备及其抗溃疡活性研究

Preparation of Cerebrosides and Study on Their Anti-ulcerogenic Activity

本文首先比较了海参和海星脑苷脂对脂肪肝大鼠肝脏脂质代谢的影响，结果表明海参和海星脑苷脂均可以显著降低肝脏脂质蓄积。

The results show that both cerebrosides can significantly reduce lipid accumulation in the liver of the rats .

建立一套用于各种海参脑苷脂分离纯化的快速高效的完整新体系。

A quickly , efficient , complete and new system is established for purification of sea cucumber cerebrosides .

研究海参脑苷脂及长链碱的抗肿瘤和抗炎活性，初步探讨其构效关系。

Studies on the anti-tumor and anti-inflammatory activities of sea cucumber cerebrosides and long-chain bases , does pilot studies on their structure-activity relationship .

鞘脂储存类疾病，如泰萨二氏病、脑苷脂沉积病和神经鞘磷脂沉积病，都涉及到连接神经细胞的凸起的多余生长和分叉。

The sphingolipid-storage diseases , Tay-Sachs , Gaucher 's and Niemann-Pick , all involve extra growth and branching of the protuberances that connect nerve cells together .

该方法的建立，为脑苷脂单体化合物的研究提供了捷径，为构效关系的深入研究提供了结构信息。

The establishment of methodology provides a new approach for analysis of cerebroside monomers , and afforded the structure information in the relationship of structure-activity reasearch . 4 .

结果表明，海参脑苷脂可以明显降低血清转氨酶活性，有效调节大鼠肝脏氧化应激状态，显著改善肝细胞坏死，显示出良好的肝损伤保护作用。

The results turns out that CSCC can attenuate liver damage in rats by reduction of the activities of serum aminotransferase , amelioration of hepatocyte necrosis and regulation of hepatic oxidative stress .

少突胶质细胞阳性率：在诱导分化条件下，半乳糖脑苷脂阳性率为65%，磷脂碱性蛋白阳性率为45%，微管相关蛋白2阳性率为10%。

Oligodendrocyte positive rate : conditions in inducing differentiation , galactose cerebroside positive rate was 65 % , phospholipid basic protein-positive rate of 45 % , microtubule-associated protein 2-positive rate was 10 % .

神经节苷脂在神经细胞膜表层内存在的一组包含半乳糖的脑苷脂显微镜下将脑膜抬起，暴露出岩浅大神经、面神经裂孔和弓状隆起。

Any of a group of galactose-containing cerebrosides found in the surface membranes of nerve cells . Lift the cerebral dura mater to exposure greater superficial petrosal nerve , facial hiatus and arcuate eminence .

在所测13种水产样品中，海星的脑苷脂和神经酰胺含量最高，在所测8种海参中叶瓜参脑苷脂含量最高。

In 13 species of aquatic products , the contents of cerebroside and ceramide of starfish are the highest , and cerebroside content of Cucumaria frondosa is the highest in eight species of sea cucumber samples .

棘皮动物脑苷脂是其中一种重要的次生代谢产物，迄今为止对其活性的研究主要集中于抗肿瘤方面，尚未发现有关其保肝护肝、防治肝脏疾患的报道。

The cerebroside from echinoderms is an important second metabolite , and the study on its biological functions mainly focused on the antitumor activity . This is the first paper to study the hepatoprotective effect of echinoderms cerebroside in animals .

诱导骨髓基质细胞表达神经细胞标记物Nestin，NSE和GFAP：脑源性神经节苷脂定向诱导细胞分化作用的研究

Induction of Neural Markers Nestin , NSE and GFAP Expression in Cultured Bone Marrow Stromal Cells : Differential Effects of Brain Gangliosides

毛细管电泳技术分离哺乳动物脑组织中神经节苷脂

Separation of Gangliosides from Mammalian Brain by Capillary Electrophoresis

目的：研究急性脑外伤后大鼠脑神经节苷脂含量的变化。

Objective : To study the changes of gangliosides in the rat brain after the acute cerebral trauma .