联芳

联芳常是副产品。

Biaryls are usually side products .

芳基-芳基键的构建是现代有机合成最重要的研究方向之一，钯催化的Suzuki偶联反应可有效构筑联芳基片段。

The study for the formation of aryl-aryl bond has become one of the most important aspects in modern organic syntheses . The Suzuki cross-coupling reaction catalyzed by palladium can effectively construct biaryl fragments .

在水中使用Pd（OAc）2/DABCO催化四苯硼钠与卤代芳烃的Suzuki反应，碘代芳烃、溴代芳烃在此条件下均可顺利发生反应而生成相应的联芳基化合物，条件温和，产率较高。

Water was found a cheap and effective reaction media in Pd ( OAc ) _2 / DABCO ) catalyzed Suzuki Cross-Coupling reaction of tetraphenylboron sodium , and aryl iodides and aryl bromides were coupled smoothly to afford corresponding aryl-aryl products in water .

Suzuki偶联反应是合成联芳基结构最有效的方法之一，近年许多用于芳基硼酸与各种卤代芳烃偶合的催化剂相继被开发。

Suzuki cross-coupling reaction is one of the most efficient methods for the construction of Caryl-Caryl bonds . In recent years , Various efficient catalyst precursors have been developed that allow aryl iodides , bromides , and chlorides to be effectively coupled with aryl boronic acids .

以芳香胺为反应底物相转移催化下合成联芳化合物

Synthesis of biaryl compounds used arylamine as substrates under phase transfer catalysis

联芳化合物的合成进展

Progress in the Synthesis of Biaryl Compounds

联芳基取代吡唑化合物为钠通道阻滞剂，用于治疗疼痛和其它病症。

Biaryl substituted pyrazole compounds are sodium channel blockers useful for the treatment of pain and other conditions .

从绿色化学的角度出发，本文将该反应成功地应用于具有联芳基结构片段的非甾体抗炎药&联苯乙酸（5）、芬布芬（6）和氟比洛芬（7）的合成。

In terms of green chemistry , this new synthetic strategy was successfully applied to the syntheses of Felbinac ( 5 ), Fenbufen ( 6 ) and Flurbiprofen ( 7 ), three nonsteroidal anti-inflammatory drugs ( NSAIDs ) bearing biaryl fragments .