联合用药

联合用药对多药耐药铜绿假单胞菌的体外活性

Drug Combination on in vitro Activities of Multi-drug resistant Pseudomonas aeruginosa

运用中效原理进行联合用药分析。

The drug combination analysis was conducted by the moderate efficiency principle .

提出首选二性霉素B及联合用药的治疗措施。

Amphotericin B in conjunction with other medicines is recommended for treating fungal septicemia .

目的：研究苯海拉明（D）与普鲁卡因（P）传导麻醉的协同作用，为临床联合用药提供理论依据。

To research synergetic anesthetic effect of diphenhydramine ( D ) and procaine ( P ) .

DNA甲基化转移酶抑制剂与胸苷酸合成酶抑制剂体外联合用药的抗肿瘤增效作用

Synergistic Anticancer Effect of DNA Methyltransferase Inhibitor Combined with Thymidylate Synthase Inhibitor in vitro

依q值评价联合用药增效情况。

The enhanced effect of associated medication was evaluated with q value .

目的观察联合用药对慢性乙型肝炎（chronichepatitisBCHB）的治疗效果。

Aim To explore the Combination Interferon and Aciclovir in the Treatment of Chronic Hepatitis B ( CHB ) .

塞来昔布组和联合用药组比较VEGF表达无差别（P0.05）。

There was no difference in VEGF mRNA level between celecoxib group and combination group ( P 0.05 ) .

本课题开展了RA动物模型的实验研究，以阐明其联合用药机制。

Our study will develope RA animal model , in order to elucidate the mechanism of combination therapy .

观察苦参碱和5-FU联合用药对胃癌裸鼠移植瘤的抑制作用，计算出相对肿瘤体积（RTV）和肿瘤抑制率（IR）；

The relative tumor volume ( RTV ) and tumor inhibition rate ( IR ) were calculated .

联合用药ADRs共106例次。

Combination drug therapy resulted in 106 ADRs times .

目的探讨胰岛素联合用药治疗磺脲类（SU）继发性失效临床疗效。

Objective To observe the clinical effect of combined use of insulin for secondary failure to sulfonylurea ( SU ) treatment .

联合用药组HDL-C水平显著高于对照组（P0.01）。

Compared with the control group , combined treatment group had Higher HDL-C level ( P0.01 ) . 3 .

联合用药组HIF-1α表达明显低于对照组，差异具有统计学意义（p0.05）。

HIF-1 α in combination group was significantly lower than the control group , the difference was statistically significant ( p0.05 ) .

基因芯片在筛选结肠癌5-Fu、MMC联合用药体外敏感性相关基因中的应用

Screening differentially expressed genes between in vitro chemosensitivity of 5-Fu plus MMC in colon cancers using cDNA microarray

揭示联合用药可直接作用于癌细胞，抑制癌细胞遗传物质DNA合成和RNA转录.阻碍了癌细胞正常代谢，加速癌细胞死亡。

O. could exert direct effects on cancer cells , and could inhibit DNA synthesis and RNA transcription , causing hindrance on cancer cell metabolism and speeding up their death .

此外，自噬和caspase的抑制剂联合用药能够明显减少细胞的死亡率。综上所述，RD在成骨肉瘤细胞中同时诱导细胞凋亡和自噬。

Moreover , RD-induced cell death was significantly restored in combination of autophagy and caspase inhibitors in osteosarcoma cells .

结果表明西曲瑞克组和西曲瑞克联合用药组的AI远远小于化疗组。

The result expresses the AI of cetrorelix group and consociation treatment groups are far and far small to the chemotherapy groups . 2 .

对多药耐药和泛耐药菌株，为减少用药量和毒副作用，提高抗菌效果，可考虑多黏菌素B与这些抗生素联合用药。

Multi-drug resistance and pan-resistant strains , in order to reduce the dosage and side effects , improve the antibacterial effect of polymyxin B which could be considered with the combination of these antibiotics . 2 .

G-CSF与GM-CSF联合用药治疗化疗后骨髓抑制的比较

Comparison between Combination of G-CSF and GM-CSF in Patients With Arrest of Bone Marrow Caused by Chemotherapy

双侧卵巢中卵泡个数各组均较治疗前明显减少（P0.01），联合用药组的卵泡数较罗格列酮、CPA组的卵泡数更少（P0.01）；

Follicle numbers in the two ovaries of patients decreased in all the therapeutic groups significantly compared with those before the treatments ( P0.01 );

结果发现联合用药时各药物的MIC几何均值比单用有显著降低，具有统计学意义（P0.05）；

Results Compared with the single agents , there were significant reductions in the geometric mean of the MIC of the combinations ( P0.05 ) .

结果：ADD的发生率9.3%，与使用抗生素种类、联合用药数量及疗程、采用医疗干预措施、年龄等因素有关。

Results : Prevalence ratio of ADD was9.3 % , the risk of ADD related to the kinds of using mix antibiotics and period of treatment , using many meddle measures for medical and age .

氯丙嗪组sIL-2R水平明显高于氯氮平组及联合用药组；

The lever of sIL-2R was significantly higher in chlorpromazine group than that in clozapine group and combined drugs group .

结果显示联合用药时各药物的最低抑菌浓度（MinimalInhibitoryConcentration，MIC）几何均值比单独用药显著降低（P<0.01）；

Compared with the single agents , there were significant reductions in the geometric mean of the minimal inhibitory concentration of the combination ( P < 0 . 01 ) .

为探讨常见病原菌对氨苄青霉素（AMP）的耐药性，为临床提供合理、联合用药依据，对从病人标本中分离的322株常见病原菌做AMP药敏试验。

To study the drug resistance of common pathogenic bacteria to aminobenzylpenicillin ( AMP ) . Method A drug sensitive test .

为了检测氟喹诺酮类药物与甲氧苄氨嘧啶（TMP）联合用药产生的作用，作者进行了环丙沙星与TMP联用的体外抑菌试验。

The effects of the combination of ciprofloxacin and trimethoprim ( TMP ) in vitro against some main veterinary pathogenic bacteria were reported .

结论HCPT、PYM单独及联合用药均对Acc-M细胞在体外有很好的抑制作用且以联合应用效果更佳。

Conclusion HCPT combined with PYM may be synergistic in the inhibition of Acc-M cells in vitro .

目的：观察麻疹疫苗和复方丹参片联合用药治疗复发性阿弗他溃疡（RAU）的治疗效果。

Objective : To observe the curative effect of measles vaccine and compound danshen tablet on curing RAU .

结论：桂枝茯苓丸和丹那唑可以抑制EM模型大鼠异位内膜的血管生成，使异位内膜萎缩，当二者联合用药时，作用更强。

Conclusion : Both GFW and danazol can affect angiogenesis of EM model rats , cause an obvious atrophy in ectopic endometrium . The effect could be enhanced when they are used synergically .