终末期肝病

终末期肝病合并门静脉血栓患者的肝移植术（附四例报告）

Liver transplantation in end stage liver disease with portal vein thrombosis ( report of 4 cases )

终末期肝病模型评分差值对失代偿期肝硬化患者预后评估的价值

The delta value of model of end stage liver disease in predicting the prognosis of patients with decompensated cirrhosis

肝硬化患者VEGF水平和终末期肝病模型评分的临床意义

The clinical significance of serum VEGF and MELD in patients with liver cirrhosis

失代偿性肝硬化（LC）是一种常见的终末期肝病。

Decompensated liver cirrhosis is one of the most common end-stage liver diseases .

1.2亿，其中慢性肝炎和肝炎肝硬化患者约3000万，每年约有30～50万人死于因HBV所致的各类终末期肝病（肝硬化、肝癌）及重型肝炎。

The number of infectious HBV is about 120 million , and about 3 million individuals are chronic hepatitis or liver cirrhosis .

肝肾联合移植（combinedliverandkidneytransplantation，CLKTx）是治疗终末期肝病合并肾功能衰竭的有效手段。

The combined liver-kidney transplantation ( CLKTx ) is a proper method to deal with the end-stage both of the liver and kidney .

目的应用终末期肝病模型（modelforend-stageLiverDisease，MELD）评分系统预测血浆置换治疗后重型肝炎患者的预后。

Objective To study prognosis of patients with fulminant hepatitis after plasma exchange treatment using MELD ( model for end-stage liver disease , MELD ) scoring system .

结论1.肝移植能够有效治疗HBV相关性终末期肝病，但应注意手术时机的选择。

OLT is an effective treatment for the HBV correlated end-stage liver disease . It is important for us to choice the optimal operation opportunity . 2 .

终末期肝病患者应用G-CSF诱导骨髓源性细胞的可行性与安全性

Feasibility and safety of G-CSF administration to induce bone marrow-derived cells mobilization in patients with end stage liver disease

目的评估终末期肝病模型（modelforend-stageLiverDisease，MELD）评分系统对慢性重型肝炎患者短期（3个月）预后的预测能力及临床应用价值。

Objective To study the clinical practical use of the model for end-stage liver disease ( MELD ) and assess its validity in predicting the prognosis of the . chronic severe hepatitis patients .

首次肝移植和再次肝移植前病人终末期肝病模型（MELD）评分平均为15.6分和23.9分；

The average MELD scores before primary transplantation and retransplantation were 15.6 and 23.9 , respectively .

在我国，乙型肝炎病毒（HBV）相关的急慢性终末期肝病逐渐成为肝移植的主要适应症。

In our country , acute or chronic HBV-related end-stage liver diseases serve as the main indication of the liver transplantation , which is likely to bring about the reinfection of HBV post-LT.

慢性HBV感染导致的肝炎肝硬化和肝癌等终末期肝病，已成为严重危害我国人民生命健康的主要疾病。

Both liver cirrhosis and hepatocarcinoma , which are serious end stage of liver diseases and caused mostly by chronic HBV infection , have been threaten to lives and healthy of Chinese people .

MELD评分预测终末期肝病肝移植术后短期生存率的研究

The study about pretransplantation MELD score in predicting short-term survival of patients with end-stage liver disease post liver transplantation

目的与传统Child-Turcotte-Pugh（CTP）评分及晚近终末期肝病的危险度评分模型（modelforend-stageLiverDisease，MELD）评分比较，探讨无创定量超声评分评估肝纤维化程度的可能性。

Objective To investigate the possibility of evaluation hepatic fibrosis by noninvasive quantitative ultrasonographic score , comparing child-turcotte-pugh ( CTP ) with model for end-stage liver disease ( MELD ) .

原位肝移植是目前公认的治疗各种良性终末期肝病唯一的有效手段，而移植肝HBV感染是其术后的主要并发症之一。

It is well accepted that the orthotopic liver transplantation ( OLT ) is the definitive therapy for patients with end-stage liver disease , and the graft HBV infection is the one of major complications .

结论终末期肝病患者术前MELD评分值越高，肝移植后早期严重并发症发生率和死亡率越高。

Conclusions A higher MELD score before liver transplantation is associated with greater likeliness of early-stage complication rate and mortality .

目的在乙型肝炎病毒（HBV）所致的终末期肝病患者肝组织内，常可见大量的胆管增生，但其发生机制及临床意义尚不清楚。

[ Objective ] Ductular proliferation is frequently observed in the liver tissue sections of patients with end-stage chronic liver disease induced by hepatitis B virus ( HBV ), but its pathogenesis and significance remain unclear .

肝移植是迄今为止已知的治疗因原发性硬化性胆管炎（PSC）导致的终末期肝病的唯一的治愈疗法。

Liver transplantation is the only curative treatment known to date for end-stage liver disease occurring as a result of primary sclerosing cholangitis ( PSC ) .

结论原位肝移植术是治疗HBV感染相关的终末期肝病的有效手段，拉米夫定加HBIG或阿德夫韦加HBIG联合应用可以有效地预防HBV的再感染。

Conclusions Orthotopic liver transplantation is an effective treatment for HBV-related end-stage liver diseases . Lamivudine + HBIG or Adefovir + HBIG offers effective prevention against hepatitis B virus reinfection .

目的：探讨MELD评分（终末期肝病模型）在评价行肝移植手术患者围手术期营养状况中的应用价值。

Objective : To investigate the clinical value of MELD ( model for end-stage liver disease ) score for evaluation of perioperative nutrition status liver transplantation candidates .

目的：应用MELD（终末期肝病评分模型）评价慢性重型肝炎的近期预后。

Objective : To evaluate the application of the Model for End-Stage Liver Disease ( MELD ) in predicting the short-term prognosis in patients with chronic severe viral hepatitis .

方法回顾性分析该研究院2000年10月￣2003年10月40例乙肝病毒相关终末期肝病肝移植术后，联合应用乙肝免疫球蛋白和Lamivudine对预防乙肝病毒复发的疗效。

[ Methods ] Retrospective analysis the effect of 40 cases liver transplantation on HBV-related diseases performed during 2000 , 10 to 2003 , 10 in our hospital with combination use of HBIG and Lamivudine .

终末期肝病模型（MELD）对重型肝炎预后评价研究失代偿期肝硬化患者的MELD评分与预后分析

Evaluation Studies of MELD to Asses the Prognosis of Patients with Severe Hepatitis ; Analysis of Model for End-stage Liver Disease Score and Prognosis on Patients with Decompensated Liver Cirrhosis

丙型肝炎最大的特点是高度慢性化，慢性化率为50%～85%。一部分HCV慢性感染者可演化成肝硬化、肝癌等终末期肝病。

The most significant character of HCV infection is its ability to cause chronic infection , the rate of which is 50 % ~ 85 % , a part of those who get chronic infection will develop cirrhosis and hepatocellular carcinomas ( HCC ) .

探讨终末期肝病模型（MELD）评分系统对预测慢性重型乙型病毒性肝炎患者短期预后的临床应用价值。

To assess the value of the model for end-stage liver disease ( MELD ) on the short-term prognosis in the patients with chronic liver failure ( chronic and severe hepatitis B ) .

目的通过观察终末期肝病模型（MELD）在终末期肝病预后预测中的作用，探讨其在临床的应用价值及人工肝支持系统在终末期肝病治疗中的效果。

Objective : To study the practical use of model end-stage liver disease ( MELD ) on clinic and the role of artificial liver support system ( ALSS ) on end-stage liver disease .

随着人们生活习惯和饮食结构的改变，NAFLD发病率不断上升，发病年龄有低龄化趋势，并且部分患者可进展到终末期肝病，因而日益受到医学界关注。

With lifestyle and dietary changes in the structure , NAFLD incidence rising incidence trend of younger age , and some patients may progress to end-stage liver disease , which is increasingly concerned about the medical profession .

目的：研究终末期肝病模型（MELD）与Child-Turcotte-Pugh（CTP）评分系统和肝硬化失代偿期患者短期（3个月）预后的关系。

Objective : To investigate the relationship between the model for end-stage liver disease ( MELD ) and Child-Turcotte-Pugh ( CTP ) scoring , and the prognosis of patients with decompensated liver cirrhosis .

1983年美国国立卫生研究院（NIH）正式确认肝移植是治疗各种原因引起终末期肝病的有效方法。

American National Institutes of Health ( NIH ) has affirmed in due form that liver transplantation offers a lifesaving treatment for individuals with terminal disease since 1983 . Since 1995 , liver transplantation has been developing rapidly in China .