端粒结合蛋白

端粒结合蛋白直接保护端粒DNA，端粒相关蛋白通过与端粒结合蛋白的相互作用间接影响端粒的功能。

Telomeric binding proteins protect telomeric DNA while telomeric associated proteins have effect on telomere through interaction with telomeric binding proteins .

目的探讨端粒酶和端粒结合蛋白（TRF）在细胞凋亡过程中的作用机制。

Objective To investigate the role of telomerase and telomere repeat binding factors ( TRF ) in apoptosis .

端粒结合蛋白TRF2的研究进展

Telomere binding protein TRF 2

端粒结合蛋白在急性白血病细胞中的表达、突变和对端粒酶作用及机理研究

Study on the Expression and Mutation of Telomere Binding Proteins in Acute Leukemia Cells and Their Effects on Telomerase

它与端粒结合蛋白结合在一起，对染色体起到了保护的作用，另外，端粒的长度和细胞增殖有很大关系。

It is combined with protein and protect the chromosome , in addition , its length has great relationship with cell proliferation .

端粒结合蛋白是特异结合在端粒不同位点并参与端粒各种功能的一类蛋白质的总称。

Telomere-binding proteins were a class of proteins which were specific binding on the different sites of telomere involved in telomere functions .

已知端粒酶活性受多种途径调控，其中端粒结合蛋白是近年来发现的一个新的调控途径。

The regulation of telomerase activity could be explained by many aspects , telomere binding protein is one of the new one .

尽管已经有一些高等植物可能的端粒结合蛋白被鉴定出来，但是他们在体内的功能还不是很清楚。

Although several potential telomere binding proteins have been identified in higher plants , their in vivo functions are still unknown at the plant level .

端粒酶的活性受多种因素的影响，端粒结合蛋白、端粒酶激活剂、端粒酶抑制剂等通过不同途径调节端粒酶的活性。

Telomerase activation is influenced by various kinds of factors , such as telomere binding protein , telomerase activator and telomerase inhibitor etc. They regulate telomerase activation through different pathways .

端粒酶·端粒序列·端粒结合蛋白

Telomerase . Telomere sequence . Telomere binding protein

端粒蛋白包括端粒双链DNA结合蛋白、端粒单链DNA结合蛋白、其它端粒相关蛋白。

Telomeric proteins is composed of double DNA binding protein , single DNA binding protein and telomeric associated proteins .

在端粒体中，端粒、端粒酶、端粒结合蛋白相互作用，共同完成对细胞基本生命活动的调节。

In telosome , the subunits interact with each other and regulate the basic activities of cells .

最近发现端粒长度的动态平衡是由端粒、端粒酶、端粒结合蛋白组成的高分子复合体&端粒体调节的。

It has been believed that the homeostasis of telomere is regulated by telosome which consists of telomere , telomerase and telomeric proteins .

随着对端粒、端粒酶研究的深入，一类被称为端粒结合蛋白的核蛋白越来越受到重视。

Along with the intense experiment work , to better characterize the telomeres and telomerase enzymes , more and more efforts have been directed to other nuclear proteins named telomere binding proteins .

端粒酶对端粒结构的稳定起着重要的作用，而端粒结构和端粒结合蛋白也影响端粒酶活性。

While telomerase plays an important role in maintenance of telomere structural stability , telomere is also involved in the regulation of telomerase activity .

该文介绍了端粒酶的性质、特点与功能，端粒序列的不同合成方式及其在生物体内的重要生理功能以及各种端粒结合蛋白的特点。

The properties and functions of telomerase , the biosynthesis and physiological functions of telomere sequences and the properties of various telomere binding proteins were reviewed .