突变频率

tū biàn pín lǜ
  • mutation frequency
突变频率突变频率
  1. 个体辐射敏感性对医用X射线工作者GPA基因突变频率的影响

    Influence of individual radiation sensitivity on GPA gene mutation frequency in medical diagnostic X-ray workers

  2. DNA损伤及修复能力是影响GPA基因突变频率个体差异的的决定因素之一。

    DNA damage and repair ability is one of determinants influencing the individual differences in GPA mutation frequency .

  3. 因此,N基因功能缺失突变频率大致为1/22000。

    Therefore , the N gene has a loss of function mutation rate of approximately 1 / 22,000 .

  4. 突变频率的分析表明,基因组包装信号序列的突变频率高于N蛋白,而N蛋白高于M蛋白。

    It seems that the mutation rate of packaging signal sequences is much higher than the N protein , while only subtle variations for the M protein .

  5. 应用这项技术,可大大提高M2代突变频率和选择效率。

    Mutation frequency and selective efficiency in M2 were obviously increased by application of the technique .

  6. 个体的辐射敏感性较高者,GPA基因突变频率较高;

    The stronger the individual radiation sensitivity , the higher the GPA gene mutation frequency .

  7. DMD基因具有突变频率高且突变形式多样之特点。

    There are high rate and different forms of mutations in the dystrophin gene .

  8. 目的研究脊髓小脑型共济失调(SCA)6型的临床特征和基因突变频率。

    Objective To study the clinical features and genetic mutation frequency of spinocerebellar ataxia ( SCA ) type 6 from Chinese kindreds .

  9. GPA基因突变频率;

    GPA gene mutation frequency ;

  10. ~(60)Co-γ射线与NaN3复合处理小麦的诱变效应&Ⅱ.诱变二代的突变频率

    Mutagenic effects of ~ ( 60 ) co gamma ray combined with nan_3 in wheat the mutation frequency of M2

  11. 结果X射线工作者的辐射敏感性存在个体差异,个体辐射敏感性是GPA基因突变频率变异的影响因素;

    Results There was individual difference in radiation sensitivity among medical diagnostic X-ray workers , which is a factor influencing GPA gene mutation frequency .

  12. STR在整个人类基因组中分布广泛,绝大多数位于非编码区,及少数在编码区,它们的生物学功能至今仍未完全阐明。STR代表基因组内不稳定的区域,比非重复DNA序列的突变频率高得多。

    STR are widely distributed humankind genome mostly in non-coding region , a few coding region , whole biological functions are not completely illustrated .

  13. 最高浓度组(4.0μg/ml)的细胞微核率及TK基因突变频率分别是对照组的8.8和15.7倍。

    The maximum induction of MN and TK mutations were 8.8 and 15.7 times compared with those of control .

  14. 中国大陆汉族人群SCA各亚型的突变频率分析及SCA6的临床和分子特征

    Frequency analysis of autosomal dominant spinocerebellar ataxias in Han population in the Chinese mainland and clinical and molecular characterization of spinocerebellar ataxia type 6

  15. 背景与目的:研究丙烯酰胺(Acrylamide,AA)对小鼠淋巴瘤L5178Y3.2.7c-tk+/-细胞tk基因突变频率的影响。

    BACKGROUND & AIM : To investigate the effect of acrylamide ( AA ) on the tk gene of mouse lymphoma cells .

  16. 血型糖蛋白A(GPA)基因突变频率在作为生物剂量计及癌的风险预测方面最大的缺陷在于个体差异大。

    The prominent disadvantage of using GPA mutation frequency as biodosimeter and cancer risk predictor is the significant individual differences .

  17. 首先,以血液中提取的基因组DNA为模板,PCR扩增经胃癌组织部分实验筛选出的四种高突变频率基因。

    First of all , the genomic DNA was isolated from peripheral blood as template and then four genes with high mutation rate which were choose from experiments of gastric cancer tissue were amplified .

  18. 结论:LP是一种罕见的常染色体隐性遗传病,中国人群中其致病基因的突变频率很低;

    Conclusion : LP is an autosomal recessive disease , and the mutation of pathogenic gene of LP is rare in Chinese people .

  19. 目的探讨个体辐射敏感性对GPA基因突变频率的影响及其校正方法。

    Objective To study the influence of individual radiation sensitivity on GPA gene mutation frequency and the way to adjust it .

  20. 老年人MBL基因ExonⅠ点突变频率及其血浆含量变化的研究

    Study on Exon ⅰ point mutation frequency of MBL gene and the changes in plasma MBL concentration in the elderly

  21. HPRT基因突变频率与染色体畸变、微核具有良好的相关性。

    The HPRT gene mutation frequencies had better linear relations with chromosome aberrations and micronuclei .

  22. 辐射诱发细胞HPRT基因位点突变频率的研究

    Study on the frequency of radiation induced HPRT site mutation and its dose effect relationship

  23. 背景与目的:研究小鼠淋巴瘤L5178Y3.2.7c-tk+/-细胞tk基因的自发突变频率和分子突变。

    BACKGROUNDAIM : To investigate the mutation frequency and molecular mutation of spontaneous mutations on the tk gene of mouse lymphoma cells .

  24. 蒙古族人MBL基因exonI54位密码子点突变频率与其血浆含量的相关性

    Correlation between point mutation frequency of MBL gene exon ⅰ and plasma MBL concentration in healthy Mongolians

  25. 汉、蒙古族人MBL基因ExonⅠ54位密码子点突变频率及其血浆含量相关性研究

    Correlation between point mutation frequency of MBL coding gene Exon 1 and MBL plasma concentration in Chinese Hans and Mongolia people

  26. 胆固醇酯转运蛋白基因373Ala→Pro和451Arg→Gln的突变频率及其对脂质代谢的影响

    Allele Frequencies of Mutations 373 Ala → Pro and 451 Arg → Gln in Cholesterol Ester Transfer Protein Gene and Their Influences on Lipid Metabolism

  27. 结果:MCLR染毒导致TK6细胞相对存活率下降,TK基因突变频率明显上升,达到对照的51倍。

    Results : TK gene mutation frequency induced by MCLR was 5-fold over control .

  28. 结论:PS-1基因外显子5~9的突变频率较低,可能不是中国人群AD的主要危险因素;

    Conclusion : The mutation frequency of PS-1 gene is quite rare and it may not be the main risk for AD in Chinese population .

  29. HCV的依赖RNA的RNA聚合酶(RdRp)缺乏校对功能,使得RNA在复制过程中错配率极高,最终导致HCV基因组中核苷酸突变频率极高,为基因分型提供了基础。

    During replication of HCV , RNA-dependent RNA polymerase ( RdRp ) frequently introduces random nucleotide errors , which results in a relatively high rate of spontaneous nucleotide substitutions .

  30. 心梗、脑卒中患者两种CETP基因突变频率与健康人无差别。

    The frequency of two CETP gene mutation had no significant difference in patients and controls .