神经发生
- neurogenesis;neurogeny
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银杏内酯B对大鼠大脑中动脉阻断再灌注后神经发生的影响
The effect of ginkgolide B on neurogenesis after brain ischemia-reperfusion in rats
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枸杞多糖对AD模型小鼠海马齿状回神经发生和小胶质细胞的影响
Effects of LBP Treat AD Mice on Hippocampal Dentate Gyrus Neurogenesis and Microglia
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内源性VEGF表达对缺血性脑损伤后成年大鼠海马齿状回神经发生影响的实验研究
The effect of endogenous VEGF gene expression on dentate gyrus neurogenesis after cerebral ischemia in adult rats
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强制运动对DG神经发生的效应有强度依赖性。
The effect of forced running on neurogenesis was intensity-dependent . Exercise .
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此外,在正常动物中,BDNF对于成人的神经发生是一种潜在的刺激质。
Moreover , in intact animals , BDNF is a potent stimulator of adult neurogenesis .
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CD24属糖基磷脂酰肌醇锚蛋白。作为P-选择素配体的黏附分子,其可调节B细胞发育和神经发生。
Glycosylphosphatidylinositol-anchored membrane protein CD24 is a ligand of P-selectin and plays a role in B-cell development and neurogenesis .
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结论BrdU标记法可以准确反映成年大鼠脑组织神经发生水平。
Conclusion BrdU labeling method can displaying the levels of neurogenesis in adult brain .
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APP/PS1双转基因Alzheimer病鼠模型海马神经发生的研究
The Research of Hippocampal Neurogenesis in the Progressive Stage of Alzheimer 's Disease Phenotype in an APP / PS1 Double Transgenic Mouse Model
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越来越多的资料表明,NSCs所处微环境中的多种因子参与神经发生的调控。
Much more documents have indicated that many factors participate in the regulation of neurogenesis in microenvironment of NSCs .
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Wnt信号通路与神经发生
Wnt Pathways and the Neurogenesis
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内源性noggin对学习记忆过程中海马神经发生的调控作用
Effect of endogenous noggin on hippocampal neurogenesis during learning and memory
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Noggin与成体神经发生的调控
Noggin and the Regulation of Adult Neurogenesis
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尼莫地平显著抑制脑缺血再灌注后海马齿状回的神经发生,其机制与下调p-ERK表达密切相关。
Pretreated Nimodipine inhibit neurogenesis in region of dentate gyrus by down-regulate p-ERK after ischemia-reperfusion .
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目的观察怀孕对小鼠海马齿状回(DG)和脑室下层(SVZ)的细胞增殖和神经发生的影响。
Objective To observe cell proliferation and neurogenesis in the pregnant mouse dentate gyrus ( DG ) and the subventricular zone ( SVZ ) .
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结论:提示内源性noggin参与调控学习记忆过程中海马的神经发生。
CONCLUSION : It indicates that noggin participates in hippocampal neurogenesis during the regulating process of memory and learning .
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含有同源异型结构(homeobox)的蛋白质是一大类DNA结合蛋白,在胚胎发育、基因表达调节、细胞分化、神经发生等方面发挥重要作用。
The proteins with ' homeobox ' ( HOX ) domain , a large family of DNA binding , play an important role in embryonic development , gene regulation , cell differentiation and neurogenesis .
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Noggin蛋白对D-半乳糖致衰老小鼠学习记忆及海马齿状回神经发生的影响
Effect of intracerebroventricular injection of noggin on learning and memory and neurogenesis in hippocampal dentate gyrus of D-galactose induced aging mice
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中、大剂量60Co-γ射线全脑照射损伤血脑屏障,进一步抑制SVZ神经发生。
Medium and large doses of 60Co - γ ray whole brain irradiation injury BBB , which further prohibited the neurogenesis in SVZ .
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目的了解碱性成纤维细胞生长因子(bFGF)对海马伞切断造成的阿尔茨海默病(AD)模型大鼠海马齿状回神经发生的影响,探讨bFGF治疗AD的前景。
Aim To study the effect of basic fibroblast growth factor ( bFGF ) on neurogenesis in dentate gyrus of rat model of AD and to explore the application prospect of bFGF in treatment of AD with unilateral fimbria fornix transection .
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继而运用反义寡核苷酸技术结合BrdU(bromodeoxyuridine,BrdU)标记、免疫细胞化学(immunocytochemistry,ICC)等方法探讨二者对成年大鼠海马神经发生的影响。
By using antisense technique combined with bromodeoxyuridine ( BrdU ) - labeling and immunocytochemistry ( ICC ) methods , the effect of noggin on hippocampus neurogenesis in adult rats was explored .
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目的观察弥漫性脑损伤后大鼠海马神经发生和神经生长因子(NGF)表达水平的变化,从分子水平探讨成年大鼠海马齿状回神经发生机制。
Objective To investigate the changes of neurogenesis and nerve growth factor ( NGF ) expression in hippocampus of adult rats after diffuse brain injury ( DBI ), and to explore the molecular mechanism of neurogenesis in adult brain .
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这些结果与单层贴壁培养系统中诱导R1细胞神经发生时的状况一致,暗示了iPSCs与ESCs具有相似的神经发生能力。
Such results were consistent with that of R1 cells when it cultures in adherent monoculture system . It also means that iPSCs share the similar neural differentiation ability of ESCs .
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结论癫癎发作可增加幼鼠齿状回颗粒细胞的神经发生,而NMDAR在癫癎后的神经发生中起着促进作用。
Conclusions PTZ - induced SE can increase the dentate granule cell neurogenesis in the developing rat . NMDAR plays an important role in neurogenesis following seizures .
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目的为了研究雌激素及其受体对神经发生的影响,观察了神经干细胞及其分化后细胞内芳香化酶(AROM)、雌激素受体(ERα和ERβ)的表达。
Objective To study the effects that estrogen exerts on neurogenesis , we observed the expression of aromatase ( AROM ) and estrogen receptors ( ER - α and ER - β) in the neural stem cells and its offspring .
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成年哺乳动物脑室下层(SVZ)和海马齿状回颗粒下层(SGZ)等保持着神经发生。
There are neural stem cells maintaining the neurogenesis in the subgranular zone ( SGZ ) of the dentate gyrus and the subventricular zone ( SVZ ) in adult mammalian brain .
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结果:神经元前体细胞的标志物DCX主要分布在五个神经发生相关区域:脑室下区、齿状回的粒下层、吻侧迁移流、嗅球和胼胝体周围。
Results : The DCX-expressing cells distribute mainly in five neurogenic areas : subventricular zone , subgranular zone , rostral migratory stream , olfactory bulb and around the corpus callosum .
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然后观察选择性谷氨酸受体拮抗剂MK-801、DNQX对脑缺血再灌注后大鼠海马齿状回神经发生的调控作用,探讨谷氨酸在神经发生中的角色;
Secondly , we observed the effects of Glu receptor blocker ( MK-801 and DNQX ) on neurogenesis in the dentate gyrus after cerebral ischemia , and discussed the role of Glu in enhanced neurogenesis .
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营养不良对幼鼠癫癎持续状态后海马神经发生影响的研究
Malnutrition increases hippocampal neurogenesis in the immature rat after status epilepticus
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神经发生对小鼠学习记忆能力的影响
The effect of neurogenesis on learning and memory of the mice
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怀孕可增加小鼠海马齿状回的细胞增殖和神经发生
Pregnancy increases cell proliferation and neurogenesis in the mouse dentate gyrus