病毒基因工程

正向和反向重复RNA介导的抗马铃薯Y病毒基因工程比较研究

Comparison of resistance to Potato virus Y mediated by direct and inverted repeats of the coat protein gene segments in transgenic tobacco plants

目的构建人源性抗HFRS病毒基因工程抗体基因的表达载体，为其进一步在真核细胞中表达奠定基础。

Aim To construct anti HFRS virus human engineering antibody expression vectors and then to express it in eukaryotic cells .

创建了一种快速高效的RNAi载体的构建和评测系统，为同时抗多种病毒基因工程的研究打下了基础。

This research erects an efficient system of constructing and evaluating RNAi vectors , which shed light on multiple virus-resistant genetic engineering .

结论预测的SARS冠状病毒S2刺突蛋白B细胞表位肽能够诱导家兔产生针对S2蛋白的抗体，为研制抗SARS病毒基因工程疫苗奠定了基础。

CONCLUSION : The predicted B cell epitope peptide of SARS coronavirus S2 spike protein can induce the antigenicity of S2 protein , which provides some fundamental data for developing engineering vaccine against SARS coronavirus infection .

为发展国产化肾综合征出血热（HFRS）病毒基因工程疫苗，选择了汉滩病毒A9株M基因片段为目的基因，构建转染质粒pJSBA9M。

In order to develope genetically engineered Chinese vaccine of HFRS , the hantaan virus A9 M genome segment of Chinese isolate was chosen as the target gene .

鸡传染性支气管重组鸡痘病毒基因工程疫苗对异源LHB株病毒攻击的免疫保护

Protection immunization of avian infectious bronchitis vaccine expressed by recombinant fowlpox virus after challenged with different IBV LHB strain

耐热可溶性戊型肝炎病毒基因工程抗原的表达

Expression of thermal stable ' soluble hepatitis E virus recombinant antigen

生物防治杆状病毒基因工程研究进展

Research Progress in Genetic Engineering of Baculovirus for Biological Control

植物病毒基因工程载体开发利用研究进展

Advances of development and utilization of plant viral vector for genetic engineering

病毒基因工程国家重点实验室

State Key Laboratory of Molecular Virology and Genetic Engineering

人源抗乙型肝炎病毒基因工程全抗体的研制

Development of recombinant human-derived IgG antibody against HBsAg

猪瘟血清抗体检测试剂盒的研制与抗猪瘟病毒基因工程疫苗的研究

Establishment of Sera Antibody Detecting Kit for Classical Swine Fever and Development of Recombinant Vaccine Against Classical Swine Fever Virus

中和性流行性感冒病毒基因工程抗体在昆虫细胞中的全基因表达、纯化及鉴定

Expression , Purification and Identification of Intact Recombinant IgG Antibody to Influenza Virus with Neutralizing Activity in Baculovirus / Insect System

目的研制人源抗甲型肝炎病毒基因工程抗体，为预防甲型肝炎病毒感染提供有效的方法。

Objective Development of recombinant human monoclonal antibody to hepatitis A virus as a emergent measure for prevention of hepatitis A virus infection .

该研究为轮状病毒基因工程疫苗的免疫方案、免疫途径及免疫保护作用等的进一步研究奠定了基础。

This laid a foundation for further study on vaccination schedule , the route of inoculation , and the immune protection of the disease .

由于此HA蛋白是原核表达产物，回避了真核表达系统复杂的操作过程和昂贵的费用，所以，这个麻疹病毒血凝素基因工程抗原有望成为一种新型、便捷的麻疹病毒诊断试剂

The results showed that the MV hemagglutinin gene engineering antigen might provide a more efficient diagnostic reagent for detection of the MV infection

猪源A组轮状病毒Vp4基因工程乳酸菌的制备及其免疫原性分析

Preparation and immunogenicity analysis of recombinant Lactobacillus expressing VP4 of A group porcine rotavirus

目的对昆虫细胞系统表达纯化的中和性流感病毒血凝素基因工程全抗体IgGIV2，IgGIV6进行体外和体内抗病毒效果的研究。

Objective Study on the antiviral effect in vivo and in vitro of recombinant antibodies with neutralization activity to influenza virus HA antigen , IgG IV 2 , IgG IV 6 obtained from expression in Baculo / insert system .

植物遗传转化技术在植物病毒抗病基因工程中的应用

Application of techniques of plant genetic transformation in resisting plant virus

抗植物病毒病基因工程的研究进展及评估

Progress and Assessment of Genetic Engineering Strategies for Virus Resistance in Plants

流感病毒血凝素基因工程抗体的抗病毒实验效果观察

Antiviral effect of recombinant antibody to influenza virus HA antigen

乙型肝炎病毒的基因工程与疫苗

Genetic Engineering and Vaccine of Hepatitis B Virus

抗甲肝病毒人源基因工程全抗体分子在杆状病毒中的表达

Baculovirus expression of two human recombinant neutralizing IgG monoclonal antibodies to hepatitis A virus

婴幼儿对乙型病毒性肝炎基因工程疫苗免疫反应调查

An investigation of immuno reaction in young children to hepatitis B virus genetic engineering vaccines

目前各类具有明确疗效的生物制品（如病毒疫苗、基因工程蛋白质和单克隆抗体等）的工业化生产已成为动物细胞培养技术发展的主要动力。

At present the industrial productions of the therapeutic biologicals ( such as viral vaccines , recombinant proteins , and monoclonal antibodies ) become the main driving force for the development of large-scale bioprocesses using animal cells .

基于重组腺病毒的狂犬病毒基因工程疫苗研究

Recombinant Replication-defective Adenovirus Based Rabies Vaccine Research

乙型肝炎病毒表位PreS1基因工程抗体的获得&天然及免疫人源单链抗体库的构建

Generation of Genetic Antibody Against Epitope PreS 1 of HBV : Construction of Na ? ve and Immune Human Single Chain Antibody Library

材料：实验于2000-09/2002-05在中国疾病预防控制中心病毒病预防控制所病毒基因工程国家重点实验室完成。

MATERIALS : The experiment was conducted in State Key Laboratory of Viral Genetic Engineering , Institute for Viral Disease Control and Prevention of Chinese Center for Disease Control and Prevention .

重组病毒载体又是当今病毒基因工程研究的热点之一，目前以动物病毒为基础设计的基因克隆及表达载体主要有取代型的重组病毒载体和重组的病毒-质粒载体。

At present , recombinant virus vector is one of the most hotspots in virus gene engineering , There are two vector type , the replaceable recombinant virus vector and the recombinant viral plasmid vector .

猪圆环病毒2型人工感染和重组腺病毒基因工程疫苗研究

Artificial Infection of Porcine Circovirus 2 and Study on the Recombinant Adenovirus Vaccine